Answers that end in a number.
What these drugs do, what dose you end up on, and what it costs when you get there. Every clinical fact is quoted from the label with its source; every price is read off the seller’s own page and dated.
84 guides · 21 programs tracked · cheapest today $69/mo, checked October 2026
Cheapest GLP-1 right now$69/mo at SnagRx, billed monthly. Checked October 2026.
$69/mo at SnagRx on SnagRx’s site ↗
Written by Julian Caraulani. Clinical statements are quoted from labels, the FDA and trials; guides marked reviewed were read by Dr. A. Goher, MD.
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Latest · The drugsMounjaro vs Rybelsus: a weekly shot against a pill Novo is replacingMounjaro is tirzepatide, a once-weekly injection; Rybelsus is semaglutide, a once-daily tablet. Both are type 2 diabetes drugs, and they have never been tested against each other. The bigger news for anyone choosing: Novo Nordisk says Rybelsus is being replaced by the Ozempic pill, which needs a new prescription. Paying cash, Mounjaro starts at $499 a month at LillyDirect, and Novo sells the Ozempic pill, not Rybelsus, at $149 to $299 a month.Recently checked
What it costsMounjaro cost 2026Lilly puts Mounjaro's list price at $1,112.16 per fill, which is what a pharmacy bills without coverage. With commercial insurance that covers it for type 2 diabetes, the Mounjaro Savings Program brings it to as little as $25 for up to three months. Paying cash, LillyDirect sells every Mounjaro strength self-pay starting at $499 a month. Zepbound, the same tirzepatide in a weight-loss box, starts lower at $299, and compounded tirzepatide lower still.9 min · checked October 2026What it costsZepbound Cost Without Insurance (2026)Without insurance, Zepbound costs $299 a month at the 2.5 mg starting dose and $399 at 5 mg, bought direct from Lilly. From 7.5 mg up the KwikPen is $449 a month as long as each refill arrives within 45 days of the last; miss that window, or buy vials, and it is $499 at 7.5 mg and $699 from 10 mg. That replaces a list price Lilly itself puts at $499 to $1,086.37 per fill. A year at the trial doses is about $5,400 on time-kept KwikPen refills and $8,388 at the regular price. Compounded tirzepatide, which is not FDA-approved, starts at $119 a month on our board.11 min · checked October 2026
What it costsRo vs Hims vs Noom vs WeightWatchers GLP-1 cost (2026)The big-name programs price two things separately, the membership and the medication, and the headline you see is usually one of them. Ro charges a $149 monthly membership ($74 a month if you prepay a year) plus $149 to $299 for branded drugs. WeightWatchers Clinic is $74 a month plus medication from $149. Calibrate is $199 a month on a three-month commitment, medication separate. Found advertises compounded GLP-1s from $99 a month on its insurance-supported tier and $169 cash on an annual plan, with no fee. Hims and Noom do not publish a price on a page we can read.10 min · checked October 2026What it costs
Prices, coupons, insurance and the arithmetic of paying cash, checked against the seller's own page.
What it costsMounjaro cost 2026Lilly puts Mounjaro's list price at $1,112.16 per fill, which is what a pharmacy bills without coverage. With commercial insurance that covers it for type 2 diabetes, the Mounjaro Savings Program brings it to as little as $25 for up to three months. Paying cash, LillyDirect sells every Mounjaro strength self-pay starting at $499 a month. Zepbound, the same tirzepatide in a weight-loss box, starts lower at $299, and compounded tirzepatide lower still.9 min · checked October 2026What it costsZepbound Cost Without Insurance (2026)Without insurance, Zepbound costs $299 a month at the 2.5 mg starting dose and $399 at 5 mg, bought direct from Lilly. From 7.5 mg up the KwikPen is $449 a month as long as each refill arrives within 45 days of the last; miss that window, or buy vials, and it is $499 at 7.5 mg and $699 from 10 mg. That replaces a list price Lilly itself puts at $499 to $1,086.37 per fill. A year at the trial doses is about $5,400 on time-kept KwikPen refills and $8,388 at the regular price. Compounded tirzepatide, which is not FDA-approved, starts at $119 a month on our board.11 min · checked October 2026What it costsRo vs Hims vs Noom vs WeightWatchers GLP-1 cost (2026)The big-name programs price two things separately, the membership and the medication, and the headline you see is usually one of them. Ro charges a $149 monthly membership ($74 a month if you prepay a year) plus $149 to $299 for branded drugs. WeightWatchers Clinic is $74 a month plus medication from $149. Calibrate is $199 a month on a three-month commitment, medication separate. Found advertises compounded GLP-1s from $99 a month on its insurance-supported tier and $169 cash on an annual plan, with no fee. Hims and Noom do not publish a price on a page we can read.10 min · checked October 2026Side effects
What these drugs do to your body, what the label says, and what to do about it.
Side effectsMounjaro Side Effects (2026)On Mounjaro's own label, the common side effects are stomach ones and they rise with the dose: nausea in 12, 15 and 18 percent of people at 5, 10 and 15 mg against 4 percent on placebo, diarrhea 12 to 17 against 9, and any gastrointestinal reaction in 37 to 44 percent against 20. Most of it happens while the dose is being raised and fades. Low blood sugar is rare on Mounjaro alone and is mainly a risk when it is added to insulin or a sulfonylurea. Below: the full table, the rare warnings, and why Zepbound's numbers for the same molecule look higher.12 min · checked October 2026
Side effectsGLP-1 Diet (2026)There is no special GLP-1 diet, but there is now a consensus on how to eat on one. A 2025 advisory from four medical societies says to build meals around fruits, vegetables, whole grains, legumes, lean proteins, nuts and seeds; limit refined carbohydrates, sugary drinks, red and processed meats, fast food and ultra-processed snacks; eat small regular meals; drink enough fluids; and put protein first, because appetite drops and muscle is at risk. During dose increases, smaller meals and avoiding fatty or high-fibre foods ease nausea.10 min · checked October 2026Side effectsGLP-1 constipation, nausea, diarrhea (2026)The four gut effects are the four most common side effects of every GLP-1, and the labels put numbers on them. On Wegovy 2.4 mg: nausea 44%, diarrhoea 30%, constipation 24%, vomiting 24%, fatigue 11%, against 16%, 16%, 11%, 6% and 5% on placebo. On Zepbound at 15 mg: nausea 28%, diarrhoea 23%, constipation 11%, vomiting 13%, fatigue 7%. They cluster around dose increases, they are the reason 6.8% of Wegovy patients and up to 6.7% of Zepbound patients stopped, and both labels prescribe the same fix: climb slower.10 min · checked September 2026Doses and injecting
The manufacturer's own ladder, week by week, and what each step costs.
Doses and injectingZepbound dosage chart (2026)Zepbound has six doses, 2.5 to 15 mg, taken once a week. The label's rule is four weeks at 2.5 mg, then 2.5 mg steps with at least four weeks on each, to a maintenance dose of 5, 10 or 15 mg. In SURMOUNT-1 those three doses lost 15.0, 19.5 and 20.9 percent of body weight over 72 weeks. Direct from Lilly each rung has a price, $299 at 2.5 mg rising to $699 at 10 mg and above, so the chart below carries the dose, the rule, the trial result and the bill in one place, plus the vial and KwikPen concentrations for anyone measuring in units.10 min · checked October 2026
Doses and injectingMicrodosing GLP-1 (2026)Microdosing a GLP-1 does not save money at a compounded seller: none of the compounded programs we track charges less for a smaller dose. Microdosing is not a medical term, and no dose below the label's starting dose has been studied for this. The one microdosing product on our board costs more a month than full-dose compounded tirzepatide at the cheapest seller we track. Where dose really moves the price is the brands, and the live numbers are below.9 min · checked October 2026Doses and injectingMounjaro Dosage Chart (2026)Mounjaro starts at 2.5 mg injected once a week. If more blood sugar control is needed, the dose goes up in 2.5 mg steps after at least four weeks on the current dose, to a maximum of 15 mg a week for adults and 10 mg for children 10 and older. Lilly sells every strength self-pay starting at $499 a month, so on the brand the price does not climb with the dose.9 min · checked October 2026The drugs
What each one is, who it is approved for, and how it differs from the one next to it.
The drugsMounjaro vs Rybelsus (2026)Mounjaro is tirzepatide, a once-weekly injection; Rybelsus is semaglutide, a once-daily tablet. Both are type 2 diabetes drugs, and they have never been tested against each other. The bigger news for anyone choosing: Novo Nordisk says Rybelsus is being replaced by the Ozempic pill, which needs a new prescription. Paying cash, Mounjaro starts at $499 a month at LillyDirect, and Novo sells the Ozempic pill, not Rybelsus, at $149 to $299 a month.7 min · checked October 2026The drugsBest GLP-1 for weight loss in 2026By weight lost, the order is settled: tirzepatide (Zepbound) first at 20.2% in the only head-to-head, then semaglutide 7.2 mg (Wegovy HD) at 18.7%, then semaglutide 2.4 mg (Wegovy) at 13.7% to 15.6%, then the pills. By what you pay, the order nearly inverts: compounded semaglutide from $69 a month, the Wegovy tablet from $149, Wegovy pen $349, Zepbound $299 to $699 by dose. The best one is where those two lists meet for your budget and your plan.12 min · checked October 2026The drugsZepbound vs Mounjaro (2026)Zepbound and Mounjaro are both tirzepatide, made by Lilly, injected weekly at the same six doses from 2.5 to 15 mg. Mounjaro is approved for type 2 diabetes and Lilly's own site says it is not a weight-loss drug; Zepbound is the same molecule approved for obesity and sleep apnoea. That label decides everything downstream: insurers cover Mounjaro for diabetes and refuse it for weight, Zepbound is the box a plan can cover for weight, and Zepbound's cash price runs $299 to $699 by dose, while LillyDirect sells Mounjaro from $499 a month at every strength, against a list price of $1,112.16 per fill.9 min · checked October 2026Buying safely
How to tell a licensed program from a bad one before you hand over a card.
Buying safelyIs Hims Legit?Yes. Hims & Hers is a real, licensed telehealth company, and as of October 2026 its weight-loss program sells FDA-approved brand-name GLP-1s: the Wegovy pill starts at $149 a month for the medication, plus a membership of $39 for the first month and $149 a month after, so about $298 a month from month two. It scores 2.9 on Trustpilot across 9,484 reviews, and FDA sent it a warning letter in September 2025 over compounded semaglutide marketing claims.7 min · checked October 2026Buying safelyIs Noom Legit?Yes. Noom is a real company, and its Noom Med arm prescribes GLP-1s through licensed clinicians. As of October 2026 its own site prices the medication-included Noom GLP-1Rx plan, which is compounded semaglutide, at $129 for the first four weeks, then $279 a month billed as $837 every 12 weeks, though the FAQ on the same page says $249. Trustpilot scores Noom 4.5 across 67,070 reviews, mostly about its app, and we found no FDA warning letter naming it.7 min · checked October 2026Buying safelyIs Henry Meds Legit?Yes. Henry Meds is a real telehealth company that prescribes compounded GLP-1s through licensed providers and, by its own account, fills them only at licensed US compounding pharmacies. As of October 2026 its plans start at $179 a month for compounded liraglutide or under-the-tongue semaglutide, and weekly semaglutide injections are $297 a month on its own price page. Trustpilot scores it 4.4 across 12,531 reviews, and we found no FDA warning letter naming it.7 min · checked October 2026News
Price moves from our weekly checks, and maker and FDA changes, each dated and sourced.
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