Checked October 2026

Zepbound costs $299 to $449 a month without insurance

$299 to $449 is the manufacturer's own self-pay price, starting dose to top dose. Through the 2 programs we track: $358 to $1,199 all in. The top price is a purchase offer that holds while each refill is within 45 days of the last; the regular price runs to $699.

Every way to pay for Zepbound, dose by dose

This page covers Zepbound's list price, savings card and doses. See the cheapest Zepbound programs, ranked by all-in price.

Insured, with the maker's savings cardas little as $25Eli Lilly's own terms, when a commercial plan covers Zepbound
The manufacturer self-pay$299 to $449the maker's own price, starting dose to top dose, per month. The top price is a purchase offer that holds while each refill is within 45 days of the last; the regular price runs to $699.
What a pharmacy pays$1,052average acquisition cost for a box of 4 single-dose pens, CMS survey for the week of September 2026
Cheapest program we track$358/moSesame Care, all in, membership included

The 2 cheapest Zepbound programs

1Sesame Care: $358 a month, month to month
2Wellorithm: $1,199 a month, month to month

Julian CaraulaniFounder, PriceTracker GLP-1

Medically reviewed by Dr. A. Goher, MDWe track prices. Clinical facts on this site are quoted from the drug's label, the FDA or the published trial, with the source and the date beside each one. We do not write medical guidance and we do not tell anyone what to take.

We re-check 21 programs every week · 333 price checks since August 2026 · How we check

Cheapest of the 2 programs we track, all in

2 verified sellers · membership fees included

$358/mo at Sesame Care on Sesame Care’s site ↗See every verified price

Meet Zepbound

Tirzepatide, prescribed for chronic weight management
A weekly injection, as a single-dose vial or a KwikPen
Doses run 2.5, 5, 7.5, 10, 12.5 and 15 mg
The strongest weight-loss result of any head-to-head GLP-1 trial to date*

*SURMOUNT-5 is quoted verbatim in the receipts below.

About the ingredient

Tirzepatide acts on both the GIP and GLP-1 receptors
Semaglutide, the molecule in Wegovy and Ozempic, acts on GLP-1 alone
The same molecule is sold as Mounjaro for type 2 diabetes
Compounded tirzepatide is the same molecule prepared by a pharmacy, without FDA approval

What it costs, plainly

List price $499 to $1,086.37 per fill
Manufacturer self-pay $299 to $449/mo on the KwikPen with on-time refills ($699 regular from 10 mg)
As low as $25/mo with commercial coverage and the savings card
The price climbs as your dose climbs, so budget for the dose you maintain on

Safety, plainly

Boxed warning: risk of thyroid C-cell tumors
Most common side effects are gastrointestinal: nausea, diarrhoea, vomiting, constipation
Not to be combined with other GLP-1 medicines
Prescription only: whether it is right for you is a clinician's call, not a price table's

On this page

Every verified price
The dose ladder
Every way to pay
How to choose
Common questions
Why trust this page
The price log

How much does Zepbound cost without insurance?

The manufacturer's own self-pay price runs $299 to $449 a month, starting dose to top dose (read October 2026).

How much does Zepbound cost with insurance?

With a commercial plan that covers it and Eli Lilly's savings card, as little as $25 for a 1, 2 or 3-month fill of the single-dose pen (Eli Lilly's terms, read October 2026).

Where is Zepbound cheapest online?

As of October 2026, Sesame Care at $358 a month all in, month to month, the lowest of the 2 programs we track that sell it. The cheapest Zepbound programs, ranked

The work we do for you

Every Zepbound price, checked October 2026.

We check Zepbound at every program that sells it, weekly, and quote the price from their own page. Each number below is that program’s real Zepbound price, never a cheaper compounded teaser used to advertise.

This drug also appears inZepbound2 sellers

Rank by2 listed

Cheapest verified

Trustpilot4.5 (4.4k reviews)Our score 6.0/10

Wegovy · Zepbound · Ozempic · Mounjaro +2

from $358/mosteady

$299 + $59/mo membership

What it costs

Medication: $299/mo · billed monthly
Membership: $59/mo
Consultation: Included in the $59/mo subscription
All in: $358/mo
Due on day one: $358

Read on sesamecare.com, October 2026

checked October 2026 · zepbound

$358/mo at Sesame Care on Sesame Care’s site ↗ · partner linkDetails

Trustpilot: too few reviews yet (2)Our score 7.8/10

Compounded sema · tirz + brand Wegovy, Zepbound +2

from $1,199/mosteady

What it costs

Medication: $1,199/mo · billed monthly
Membership: none
Consultation: Free
All in: $1,199/mo
Due on day one: $1,199

Read on wellorithm.com, October 2026

checked October 2026 · zepbound

$1,199/mo at Wellorithm on Wellorithm’s site ↗ · partner linkDetails

What Zepbound does, beyond the scale

See every price

The most weight lost, head to head

20.2% mean body-weight reduction at 72 weeks in SURMOUNT-5, against 13.7% for semaglutide, across 751 adults. It is the only trial that put the two molecules against each other.*

Two pathways, not one

Tirzepatide acts on both the GIP and GLP-1 receptors. Semaglutide acts on GLP-1 alone, which is the leading explanation for the gap in the head-to-head result.

The price climbs with the dose

The manufacturer's self-pay price runs $299 at the starting dose and $449 from 7.5 mg on the KwikPen while each refill is within 45 days; the regular maintenance price is $699. Budget for where you end up, not where you begin.*

Zepbound carries a boxed warning for thyroid C-cell tumor risk and should not be combined with other GLP-1 medicines. The most common side effects are gastrointestinal: nausea, diarrhoea, vomiting and constipation. This is a prescription drug: whether it is right for you is a conversation with a licensed clinician, not a price table.

Is Zepbound the right price for you?

Same appetite pathway, very different needles, prices, and evidence. Every column links to its live prices.

Worth knowing before you buy: Compounded semaglutide starts at $69/mo, $289 less than Zepbound on the same appetite pathway. Different medicine, different evidence, real saving.

ZepboundThis pageStarts at$358/moon this pageHow to takeOnce-daily pillActive ingredientTirzepatide

Wegovy penStarts at$208/mobrandHow to takeWeekly injectionActive ingredientSemaglutideSee prices →

Compounded semaglutideStarts at$69/mocompoundedHow to takeWeekly injectionActive ingredientSemaglutideSee prices →

Your dose will climb.So will the bill.

Starting low isn’t a trick, it’s clinical practice: it eases the side effects in. But the advertised price is the starting-dose price. Budget for the tier you’ll maintain on, not the one you start on.

Compare sellers

Manufacturer self-pay, by dose

manufacturer price verified October 2026

2.5 mg$299/mostarting dose

5 mg$399/mo

7.5 mg$449/moKwikPen purchase offer, kept while each refill is within 45 days; regular price $499 (vials $499)

10 / 12.5 / 15 mg$449/mothe maintenance range; KwikPen purchase offer, kept while each refill is within 45 days; regular price $699 (vials $699)

The climb, step by step

1Ease in2.5 mg

The lowest tier, and the one every advertised price quotes. Nobody's bill stays here.Manufacturer self-pay: $299/mo

2Step up5 mg

The first step up, and the bill rises $100/mo with it.Manufacturer self-pay: $399/mo

3Build7.5 mg

The middle of the ladder, $100/mo above the tier below.Manufacturer self-pay: $449/mo

4Maintain10 / 12.5 / 15 mg

The top of the ladder. All three strengths cost the same at the manufacturer's self-pay price, so the bill stops climbing here.Manufacturer self-pay: $449/mo

A year of Zepbound, honestly.

Month one is the number everyone advertises. This is the other one: twelve months, your dose climbing, membership fees counted. The assumptions are yours to set.

How fast your dose climbs

Compared against

$892

is what a year costs you extra at the manufacturer’s published prices instead of Sesame Care’s, once your dose climbs and the membership fee is counted.

Manufacturer price that month Sesame Care $358/mo all in

Each bar is one month at the manufacturer’s published price. The dark part is what you pay above Sesame Care's line. Reaching 10 / 12.5 / 15 mg by month 4.

Manufacturer, twelve months: $5,188
Sesame Care, twelve months: $4,296

Dose prices are the manufacturer’s published self-pay ladder, including the $299 offer that applies automatically at 14.5 mg and above while refills stay inside its 45-day window; the seller price is the one we last verified. Nobody can promise a price holds for a year, and how fast anyone climbs doses is a clinical decision, which is why both are controls here and not claims.

Every way to pay for Zepbound

Commercially insured

As low as $25/mo

for a one- or three-month supply of single-dose pens, when your plan covers Zepbound. Government beneficiaries are excluded and savings are capped, so confirm with your plan before counting on it.

Cash, no insurance

$299 to $449/mo

The manufacturer's self-pay prices climb with dose: $299 at 2.5 mg, $399 at 5 mg, then $449 for the 7.5 to 15 mg KwikPen while each refill is within 45 days ($499 at 7.5 mg and $699 above otherwise, and for vials). The programs below bundle the prescribing visit and are ranked on what actually leaves your account.

The cheaper molecule

Compounded is far less

The same molecule compounded runs a fraction of these prices, but it is not FDA-approved and the FDA has moved to close that route. We track both so the trade is visible.

What insurers publish about Zepbound

Coverage is decided by your specific plan, not just the insurer. Each sheet quotes the insurer’s own words and tells you exactly what to ask.

The same molecule, three ways to buy it. Manufacturer prices are its own published self-pay list and carry no link; program prices are all in, membership included, read off each seller’s own page.

Tirzepatide: Zepbound vs compounded, per month and per year
Route	Per month	12 months at this price
Zepbound, self-pay from the manufacturer^[1]2.5 mg, starting dose	$299	$3,588
Zepbound, self-pay at the top of the ladder^[1]7.5 mg, KwikPen purchase offer, kept while each refill is within 45 days; regular price $499 (vials $499)	$449	$5,388
Zepbound through Sesame Carecheapest partner program selling it, month to month	$358	$4,296
Compounded tirzepatide through Collectivecheapest partner program, all in, month to month	$85	$1,026

Compounded tirzepatide at Collective is $213 a month under Zepbound’s starting self-pay price, $2,561 over a year at those prices. Zepbound is FDA-approved; compounded tirzepatide is not.

Cheapest compoundedCollective, $85/mo all in month to month. Checked October 2026.

$85/mo at Collective on Collective’s site ↗

How to choose a Zepbound program

How to choose a Zepbound program: 7 checks

Price ranks the list. These decide whether the cheapest is cheapest for you. Each count is from the programs on this page, today.

The price at your dose: Few sellers publish dose prices; Advertised prices are usually the starting dose. A seller that charges more as you step up can end up dearer than one with a higher entry price.
How long you commit: 2 of 2 sell Zepbound month to month; 2 of 2 publish cancel-anytime terms. A low price that needs a 6 or 12-month prepay is a loan to the seller if you stop early.
Fees on top: 1 of 2 add a membership fee; None charge a separate consultation. We rank on the all-in price so a fee cannot hide.
Insurance: 1 of 2 take insurance; Most cash programs cannot bill your plan. If your plan covers a brand GLP-1, a copay can beat every cash price here.
Brand or compounded: 1 of 2 also sell an FDA-approved brand; Compounded versions are cheaper and not FDA-approved. If you want the approved drug later, a seller that stocks both saves a switch.
Who stands behind it: 2 of 2 say who does the prescribing; A real program names its clinician network and its pharmacy. LegitScript certifies telehealth sellers; check a certificate on legitscript.com, not on a badge the seller hosts.
Where you live: 2 of 2 ship to all 50 states; State rules decide who can prescribe and dispense. Check your state before you pay an intake fee.

Zepbound price: common questions

How much does Zepbound cost without insurance?

The manufacturer lists Zepbound at $299 to $449 a month self-pay, depending on the dose. The cheapest program we track that sells it is Sesame Care at $358 a month all in, checked October 2026.

Where is the cheapest place to get Zepbound?

Sesame Care, at $358 a month all in month to month. We compare 2 programs on their own published prices, membership fees included, and re-check every week.

Does Zepbound cost more at a higher dose?

At the manufacturer, yes: 2.5 mg is $299, 5 mg is $399, 7.5 mg is $449, 10 / 12.5 / 15 mg is $449 a month self-pay. Some programs hold one price at every dose; each seller's terms are on this page.

Will insurance cover Zepbound?

It depends on your plan, not the drug: many plans cover GLP-1s for type 2 diabetes and exclude them for weight loss, and coverage changes by employer and year. Our coverage pages quote what each major insurer publishes; if your plan says no, the cash prices on this page are the fallback.

Can I pay for Zepbound with an HSA or FSA?

Usually, for the medication. The IRS counts "prescribed medicines and drugs" as medical expenses, and an HSA pays for "medical care" as defined in Code section 213(d) (IRS Publications 502 and 969, read October 2026). Program fees count when the weight loss is "a treatment for a specific disease diagnosed by a physician (such as obesity...)". Your plan administrator decides what it reimburses, so check before you pay; we track prices, not tax rules.

Do I need a prescription for Zepbound?

Yes. Every GLP-1 here is sold on a prescription from a licensed clinician after an intake; 2 of the 2 programs we track say who does the prescribing, and none charges a separate consultation fee. FDA says compounded drugs "should only be used in patients whose medical needs cannot be met by an FDA-approved drug", so a seller that ships without assessing you is a red flag.

Why trust this page, and our sources

Why trust this page

PricesRead from each seller’s own page and dated, weekly. 26 recorded checks across 2 sellers since August 2026. How we verify
OrderPrice only, all in. We earn a commission from some programs and it never moves a row. How we make money
Written byJulian Caraulani, Founder, PriceTracker GLP-1.
Clinical reviewDr. A. Goher, MD reviews the clinical statements only, never prices, rankings or which programs pay us.

We track prices. Every clinical and manufacturer claim about Zepbound on this page is quoted below in its source’s own words, with the date we read it. We do not write medical guidance and we do not tell anyone what dose to take.

Guides on Zepbound

Tirzepatide Cost 2026What it costs
What Is Zepbound (Tirzepatide)?The drugs
Zepbound (tirzepatide) side effects by dose (2026), per labelSide effects

References

Eli Lilly, Zepbound cost information, read October 2026
The list price of Zepbound is $499 - $1,086.37 per fill, but the amount you pay will largely depend on your prescription drug insurance plan. ... Available through Zepbound self-pay, Zepbound is offered as a 4‑count single‑dose vial (0.5mL) and a single‑patient‑use KwikPen (2.4mL, 0.6mL/dose) in doses of 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg and 15mg, with direct‑to‑patient pricing of $299, $399, $499, $699, $699 and $699 respectively. ... If you have commercial drug insurance with coverage for Zepbound, you may be eligible to pay as low as $25 for a one- or three-month supply Zepbound single-dose pens.
IRS Publication 502, Medical and Dental Expenses (Medicines; Weight-Loss Program), read October 2026
You can include in medical expenses amounts you pay for prescribed medicines and drugs. A prescribed drug is one that requires a prescription by a doctor for its use by an individual. ... You can include in medical expenses amounts you pay to lose weight if it is a treatment for a specific disease diagnosed by a physician (such as obesity, hypertension, or heart disease).
IRS Publication 969, Health Savings Accounts and Other Tax-Favored Health Plans, read October 2026
In general, “qualified medical expenses” means amounts paid by the HSA beneficiary for “medical care” (as defined in Code section 213(d)) ... but only to the extent the amounts are not compensated for by insurance or otherwise. ... Qualified medical expenses are those specified in the plan that would generally qualify for the medical and dental expenses deduction.
Eli Lilly, Zepbound KwikPen purchase offer terms, read October 2026
You will automatically receive the $449 purchase offer on your first purchase of the 7.5 mg, 10 mg, 12.5 mg, or 15 mg Zepbound single-patient-use KwikPen. To continue to be eligible for this purchase offer, you must complete your refill purchase of the Zepbound single-patient-use KwikPen within 45 days of the delivery/received date of your previous Zepbound single-patient-use KwikPen prescription fill. ... Regular price for a 1-month supply of Zepbound single-patient-use KwikPen is $299 for 2.5 mg, $399 for 5 mg, $499 for 7.5 mg, $699 for 10 mg, $699 for 12.5 mg, and $699 for 15 mg.
American College of Cardiology on SURMOUNT-5 (tirzepatide vs semaglutide, head to head), read October 2026
at 72 weeks, the least-squares mean percent change in body weight was −20.2% for tirzepatide users vs. −13.7% for semaglutide users (p<0.001)
CMS National Average Drug Acquisition Cost (NADAC), data.medicaid.gov, published October 2026; package sizes from FDA's NDC Directory, read October 2026

Three programs to consider next

The three cheapest partner programs for Zepbound, in price order, all in per month.

1Sesame CareZepbound KwikPen (brand tirzepatide), month to month$358/mo$358/mo at Sesame Care
2WellorithmZepbound Pen (brand tirzepatide), month to month, no membership$1,199/mo$1,199/mo at Wellorithm

Watch on GLP-1 TV

Watch: Zepbound week by week, side effects, how to use it

All 303 videos

2:08Ozempic, Mounjaro, Wegovy, Zepbound: Who can take which one? | Ohio State Medical CenterOhio State Wexner Medical Center · 3.6M views

2:49How to Inject Zepbound - Step-by-step DemonstrationDrugs.com · 998K views

9:53Best foods to eat on GLP-1 Ozempic, Mounjaro, Zepbound, Wegovy DietGLP-1 Hub · 545K views

Public YouTube videos, most-watched first. Personal experiences, not medical advice.

The price log

Each trail is one seller’s price over the year. The hairline is modeled: a plausible walk that ends on the price we verified. The solid green is our own record, checked weekly since August 2026 and never rewritten. Only real checks are counted or dated below.

30 checks · 2 sellers

Sesame CareLatest verified$299/moSeptember 2026verified since September 2026Since September 2026Steady

no change in 24 verified checks

WellorithmLatest verified$1,199/moMarverified since August 2026Modeled from $1,491↓ $292

no change in 6 verified checks

Zepbound prices move. We check weekly.

Get the weekly price email, with Zepbound first, or bookmark this page: it always shows today’s number.

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