GLP-1 TV · Patient story · views checked Oct 2026
5mg Zepbound Results After 2 Months | Honest Review
Our summary
In this video, Alexis of the Simply Alexis Hope channel gives a two-month update on taking Zepbound at 5mg. She says she has gone from 209 pounds in February to 179.7 pounds on the day of filming, a loss of about 30 pounds. Her goal weight is 150 pounds, which she describes as a target for feeling healthy rather than a point where she would stop the medication. She says she does not rely on BMI and that her nutritionist agrees it is not the best measure.
One person's experience, in their words. Not medical advice.
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What else the video covers
She describes how the 5mg dose changed her appetite. At 2.5mg, she says, cravings were still present, but at 5mg she has barely had any, and she now has to schedule meals and make an effort to eat protein and vegetables. She says portions are small, for example half a banana and half a cup of yogurt at breakfast, and that smoothies and protein shakes help. She mentions having PCOS and insulin resistance, so she needs to eat to avoid dizziness and feeling sick.
Alexis lists her side effects: nausea that comes and goes, a strong gag reflex, tiredness, stomach pain on the right side after injecting in her stomach, heartburn, chills after the shot, and ongoing constipation. She says she now injects at night on weekends and has gone back to her arms. For constipation she describes using half a cap of Miralax daily and milk of magnmagnesia once. She also covers walking for exercise, non-scale victories, and her plan to stay on 5mg for a few months.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 0:30 She says she dropped from 209 pounds in February to 179.7 pounds, with a goal weight of 150 pounds.
- 2:00 She says food noise was quiet at 2.5mg and mostly gone at 5mg, so she now has to schedule meals.
- 6:42 She reports nausea, a strong gag reflex, and tiredness, and says she takes her shot at night on weekends.
- 8:13 She says injecting in her stomach brought pain on the right side for two or three days, so she returned to her arms.
- 10:01 She describes chills after the shot, heartburn, and constipation managed with half a cap of Miralax daily.
- 17:00 She says she plans to stay on 5mg for a few months and values non-scale victories.
Key moments
From the creator's own chapters. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- Zepbound
- Doses mentioned
- 5 mg
- Point in the journey
- Month 2
- Side effects mentioned
- nausea, constipation, fatigue and heartburn or reflux
- Who is speaking
- Patient
Questions this video answers
How much weight did she lose on 5mg Zepbound after 2 months?
Alexis says she went from 209 pounds in February to 179.7 pounds on the day of filming, about 30 pounds down. Her goal weight is 150 pounds.
What side effects did she have on Zepbound 5mg?
She reports nausea, a strong gag reflex, tiredness, stomach pain after injecting in her stomach, heartburn, chills after the shot, and constipation. She says the nausea and heartburn come and go.
How did Zepbound 5mg change her appetite and eating?
She says food noise was quiet at 2.5mg and cravings were nearly gone at 5mg. She now has to remember to eat, keeps portions small, and focuses on protein and vegetables.
How does she deal with constipation on Zepbound?
She says she puts half a cap of Miralax in her water every day, and took milk of magnesia once when badly backed up. She notes that Smooth Move tea did not work the first time she tried it.
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Read next
Our guides closest to what this video covers, with prices checked weekly.
- Zepbound dosage chart: every tirzepatide dose, the escalation rule, what each rung lost in the trial, and what it costs
Zepbound has six doses, 2.5 to 15 mg, taken once a week. The label's rule is four weeks at 2.5 mg, then 2.5 mg steps with at least four weeks on each, to a maintenance dose of 5, 10 or 15 mg. In SURMOUNT-1 those three doses lost 15.0, 19.5 and 20.9 percent of body weight over 72 weeks. Direct from Lilly each rung has a price, $299 at 2.5 mg rising to $699 at 10 mg and above, so the chart below carries the dose, the rule, the trial result and the bill in one place, plus the vial and KwikPen concentrations for anyone measuring in units.
- Zepbound side effects: the label's table by dose, who actually quits, and how it compares to semaglutide
Zepbound's label puts a number on every common side effect at each of its three maintenance doses. Nausea runs 25 to 29 percent against 8 on placebo, diarrhoea 19 to 23, vomiting 8 to 13, constipation 11 to 17. Across the two approval trials, 4.8 to 6.7 percent of people stopped the drug because of side effects, against 3.4 percent on placebo, and most of those who quit did so in the first months, from gut effects during dose escalation. Below that table are the rarer things the label warns about, with the trial rates where it gives them, and the honest comparison to Ozempic's table.
- How to get Zepbound: who qualifies, who prescribes it, and the four ways to pay
Zepbound is a prescription drug approved for adults with obesity, or overweight with at least one weight-related condition, which the trials defined as a BMI of 30, or 27 with a comorbidity. Any licensed prescriber can write it, including online. Then it is a payment question with four answers: a commercial plan that covers it brings it to $25 with Lilly's card; Lilly sells it direct for $299 to $699 a month by dose; a plan that refuses can be appealed; and compounded tirzepatide, the same molecule without FDA approval, starts at $85 on our board.
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