GLP-1 TV · Patient story · views checked Oct 2026
Zepbound (5mg) Weight Loss Update | 90 Days on Tirzepatide (GLP‑1)
Patient story
Our summary
In this week 12 update, Grace of the Losing It Grace channel reviews her first three months on Zepbound. She says she is still on the 5mg dose, injects in the morning, and still tenses up before pressing the button. She describes her side effects this week as mild, mainly constipation, which she says she manages with daily magnesium and water. She also says her provider told her to cut back from about a gallon of water a day after blood work suggested over-hydration.
One person's experience, in their words. Not medical advice.
Where Zepbound costs least today
The three cheapest partner programs for Zepbound, all in per month, checked weekly. Brand Zepbound and compounded versions are different products; each row says which it is.
What else the video covers
She recaps a rash that appeared in week 10 at an injection site and in the same spot on the opposite leg. According to her, an allergist thought it was likely contact dermatitis rather than an allergic reaction, and she keeps antihistamines and cortisone on hand. She plans to take her first 7.5mg injection at the doctor's office so she can be monitored for an hour. Her weigh-in was 252.4 lb, which she says is 13 lb lost in three months, with no loss this week. She links the stall to her period and constipation, and she talks about feeling discouraged when comparing herself with viewers who lost more.
Grace also lists creators she follows, describes a typical day of meals, and says her appetite returns on days five to seven after each injection. She says she is not counting calories, estimates 1,500 to 1,700 calories a day, and exercises three times a week with walks and 20-minute home strength videos. She closes with plans for weekly weigh-ins, a what-I-eat video including a cruise, and a possible Q&A. All doses, results and estimates are her own experience, not medical advice.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 1:32 Grace says she is at week 12 on the 5mg dose of Zepbound, with a morning injection routine and only mild constipation this week.
- 2:33 She says her provider asked her to reduce her roughly one gallon a day water intake after blood work pointed to over-hydration.
- 3:33 She recounts a week 10 rash at an injection site and the opposite leg, which an allergist thought was likely contact dermatitis.
- 4:35 She reports weighing 252.4 lb, 13 lb down in three months, with no loss this week.
- 8:35 She says appetite returns on days five to seven after her injection and that she is not calorie counting, estimating 1,500 to 1,700 calories a day.
- 12:19 She says she moves three times a week with walks and 20-minute strength videos, aiming for habits she can keep after the medication.
Key moments
From the creator's own chapters. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- Zepbound and tirzepatide
- Doses mentioned
- 5 mg and 7.5 mg
- Point in the journey
- Day 90
- Weight loss mentioned
- 100 lb
- Who is speaking
- Patient
Questions this video answers
How much weight did she lose on Zepbound in 3 months?
Grace says she weighed 252.4 lb at week 12, which she describes as exactly 13 lb lost over three months on the 5mg dose. She notes she did not lose any weight in the most recent week.
What side effects does she report on Zepbound 5mg?
She says this week's side effects were very mild, mainly constipation, which she manages with daily magnesium and drinking water. She also describes a rash at an injection site and on the opposite leg in week 10, which her allergist thought was likely contact dermatitis.
Does Zepbound stop her appetite completely?
Grace says it has not removed her hunger entirely at 5mg. She reports appetite creeping back on days five, six and seven after her injection, and she expects a higher dose may suppress it more.
How does she plan to handle the move to 7.5mg?
She says she will do the first 7.5mg injection at her doctor's office so staff can monitor her for an hour. She says she wants this for peace of mind after the earlier rash.
Videos on the same question
The closest videos in the library by what is said in them, not by title.
1 Month on Zepbound | Week 4 Results + Starting 5mg (Weight & Inches Lost)In this video, a creator who shares lifestyle and faith content covers her fourth week on Zepbound and the start of her second month at 5mg.
5mg Zepbound Results After 2 Months | Honest ReviewIn this video, Alexis of the Simply Alexis Hope channel gives a two-month update on taking Zepbound at 5mg.
One Month Zepbound Journey | Weight Loss Results & Side Effects | 2.5 mgIn this update from the Zepbound and Beyond channel, Anita says she has finished four weeks on Zepbound at 2.5 mg.
GLP-1 Update - 7.5MG IS MY MAGIC DOSE!!! WEIGHTLOSS JOURNEY; ZEPBOUND/TIRZEPATIDEKeisha, who runs the channel Keeping Up with Keisha, gives an update on moving up to 7.5 mg of tirzepatide (Zepbound).
Zepbound 3 Month Update | Final Shot, Honest Side Effects + Doctor Q&AIn this video, Chase documents the third month of using Zepbound, covering February 10 to February 28.
Zepbound Journey Week 1-4: My Experiences and Thoughts #zepbound #glp1In this video, the creator looks back at her first month on Zepbound, a GLP-1 medication she says is used for weight loss.
About Losing It Grace
Patient story, 23.2K subscribers. 8 of their videos are in GLP-1 TV, 161K views between them, mostly on Zepbound, Wegovy, Compounded tirzepatide.
- Tirzepatide Weight Loss by Dose 💉Which One Worked Best? 75+ LBS Lost
- I Switched to Compounded Tirzepatide After Zepbound
- I Switched to the Zepbound KwikPen: User Guide + 15mg Tirzepatide Titration
Read next
Our guides closest to what this video covers, with prices checked weekly.
- Zepbound dosage chart: every tirzepatide dose, the escalation rule, what each rung lost in the trial, and what it costs
Zepbound has six doses, 2.5 to 15 mg, taken once a week. The label's rule is four weeks at 2.5 mg, then 2.5 mg steps with at least four weeks on each, to a maintenance dose of 5, 10 or 15 mg. In SURMOUNT-1 those three doses lost 15.0, 19.5 and 20.9 percent of body weight over 72 weeks. Direct from Lilly each rung has a price, $299 at 2.5 mg rising to $699 at 10 mg and above, so the chart below carries the dose, the rule, the trial result and the bill in one place, plus the vial and KwikPen concentrations for anyone measuring in units.
- What is Zepbound? Tirzepatide explained: what it treats, how it works, and what it costs
Zepbound is Eli Lilly's brand of tirzepatide, a once-weekly injection that acts on two hormone receptors, GIP and GLP-1. The FDA label approves it, with diet and exercise, for weight reduction in adults with obesity or overweight plus a weight-related condition, and for moderate to severe obstructive sleep apnea in adults with obesity. In the SURMOUNT-5 trial it produced 20.2% average weight loss at 72 weeks against 13.7% for semaglutide. Lilly sells it self-pay from $299 a month.
- Mounjaro for weight loss, and why Zepbound exists
Mounjaro is tirzepatide approved for type 2 diabetes. Zepbound is the same molecule from the same maker, approved for weight management, and it goes to the same 15 mg. So unlike Ozempic and Wegovy, there is no dose ceiling pushing you from one to the other: the reason people move is coverage and cash price, not strength. Using Mounjaro for weight is off-label and a prescriber's decision. In the one head-to-head trial, tirzepatide beat semaglutide, 20.2% mean body-weight loss at 72 weeks against 13.7%.
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