GLP-1 TV · Patient story · views checked Oct 2026
Zepbound 3 Month Update | Final Shot, Honest Side Effects + Doctor Q&A
Patient story
Our summary
In this video, Chase documents the third month of using Zepbound, covering February 10 to February 28. She says she started the month at 283.15 lbs and finished at 274.50 lbs, and she was on 5 mg for the month. She weighs in on most days and describes small gains from eating more at night and from her period. She says she combines the medication with gym workouts, a dietitian's guidance and mindful eating.
One person's experience, in their words. Not medical advice.
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What else the video covers
She describes her side effects. Constipation was the main one, and she says a daily stool softener (Colace) helped, though not right away. By the end of the month she was taking two each morning. She also mentions tiredness, gas and burping, stomach aches, nausea, and a dry mouth and throat around the third shot of the month. She says she gets very hungry a day or two before each injection. She switched her final shot of the month to the inner thigh to see whether that would ease the constipation, and she notes that 5 mg was hard to find because of a shortage.
The middle of the video follows her 3-month visit with her bariatric surgeon, Dr. Mady, who performed her sleeve in 2021. The doctor says she is down 29 lbs since starting the medication in December and 101 lbs from her highest weight, and she plans to keep the 5 mg dose and see her in eight weeks. In a short Q&A, the doctor compares semaglutide and tirzepatide, discusses GLP-1 use after bariatric surgery, ways to manage side effects, insurance coverage and weaning off the medication.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 0:04 She starts a daily stool softener (Colace) to head off constipation and reports more regular bowel movements within a few days.
- 0:56 Chase weighs in at 281.50 lbs on February 10 and says her main symptom on 5 mg is constipation, plus some tiredness.
- 12:20 She reaches 279 lbs after her second 5 mg shot and says she has finally left the 280s.
- 21:30 At her 3-month visit, her bariatric surgeon says she is down 29 lbs since December and 101 lbs from her highest weight, and keeps her at 5 mg.
- 27:00 The doctor answers questions on semaglutide versus tirzepatide, side effect management, insurance and weaning off the medication.
- 38:18 Chase injects her last February dose in the inner thigh, then ends the month at 274.50 lbs and recaps her side effects.
Key moments
From the creator's own chapters. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- Zepbound
- Doses mentioned
- 2.5 mg, 5 mg and 7.5 mg
- Point in the journey
- Month 3
- Side effects mentioned
- nausea, constipation, fatigue and bloating
- Who is speaking
- Patient
Questions this video answers
How much weight did she lose in the third month on Zepbound 5 mg?
Chase says she was at 283.15 lbs on February 3 and 274.50 lbs on February 28. Her surgeon also said she was down 29 lbs since starting the medication in December.
What side effects did she have on Zepbound 5 mg?
She says constipation was the biggest one, along with tiredness, gas, burping, stomach aches, some nausea, and a dry mouth and throat around the third shot of the month. She says a stool softener helped with the constipation.
What does a bariatric surgeon say about using Zepbound after sleeve surgery?
The doctor says sleeve patients on average lose around 60 to 70% of excess body weight, and that the medication seems to help patients who plateau early continue losing. She calls a combination approach a good way to get more weight loss.
Does the doctor say patients can come off Zepbound?
The doctor says she hopes her weight loss surgery patients can wean off the medication and keep the weight off, but notes there are no real studies on weaning. She mentions one short European study with six months of maintenance after a long taper.
Videos on the same question
The closest videos in the library by what is said in them, not by title.
Zepbound Month 4 & 5 Update | Weigh-Ins, Side Effects, Doctor Visit & Dosage Change 💉In this video, Chase covers her fourth and fifth months on Zepbound, from a March 13 weigh-in at 268.3 through the end of April.
8 Months on Zepbound: Weight Loss, Side Effects, Insurance Denial & Why I’m Switching to WegovyChase, a creator who documents her weight loss, covers about eight months on Zepbound in this video, mostly through weigh-ins and shot-day recordings.
5mg Zepbound Results After 2 Months | Honest ReviewIn this video, Alexis of the Simply Alexis Hope channel gives a two-month update on taking Zepbound at 5mg.
Zepbound (5mg) Weight Loss Update | 90 Days on Tirzepatide (GLP‑1)In this week 12 update, Grace of the Losing It Grace channel reviews her first three months on Zepbound.
Why Wegovy Was a 0/10 for Me (Zepbound ➝ Wegovy ➝ Mounjaro | Side Effects, Insurance, Supplements)Chase, who has weight loss surgery in her history, documents her switch from Zepbound (10 mg) to Wegovy and then to Mounjaro.
ZEPBOUND: SULFUR BURPS & GASTRITIS | URGENT CARE VISITKesha Dixon, who says she is a registered nurse working in emergency room medicine, describes her first urgent care visit after 17 months on GLP-1 medications.
About Chase💕
Patient story, 4K subscribers. 5 of their videos are in GLP-1 TV, 77.7K views between them, mostly on Zepbound, Wegovy, Mounjaro.
- 8 Months on Zepbound: Weight Loss, Side Effects, Insurance Denial & Why I’m Switching to Wegovy
- Why Wegovy Was a 0/10 for Me (Zepbound ➝ Wegovy ➝ Mounjaro | Side Effects, Insurance, Supplements)
- Zepbound Month 4 & 5 Update | Weigh-Ins, Side Effects, Doctor Visit & Dosage Change 💉
Read next
Our guides closest to what this video covers, with prices checked weekly.
- Zepbound dosage chart: every tirzepatide dose, the escalation rule, what each rung lost in the trial, and what it costs
Zepbound has six doses, 2.5 to 15 mg, taken once a week. The label's rule is four weeks at 2.5 mg, then 2.5 mg steps with at least four weeks on each, to a maintenance dose of 5, 10 or 15 mg. In SURMOUNT-1 those three doses lost 15.0, 19.5 and 20.9 percent of body weight over 72 weeks. Direct from Lilly each rung has a price, $299 at 2.5 mg rising to $699 at 10 mg and above, so the chart below carries the dose, the rule, the trial result and the bill in one place, plus the vial and KwikPen concentrations for anyone measuring in units.
- Zepbound side effects: the label's table by dose, who actually quits, and how it compares to semaglutide
Zepbound's label puts a number on every common side effect at each of its three maintenance doses. Nausea runs 25 to 29 percent against 8 on placebo, diarrhoea 19 to 23, vomiting 8 to 13, constipation 11 to 17. Across the two approval trials, 4.8 to 6.7 percent of people stopped the drug because of side effects, against 3.4 percent on placebo, and most of those who quit did so in the first months, from gut effects during dose escalation. Below that table are the rarer things the label warns about, with the trial rates where it gives them, and the honest comparison to Ozempic's table.
- What is Zepbound? Tirzepatide explained: what it treats, how it works, and what it costs
Zepbound is Eli Lilly's brand of tirzepatide, a once-weekly injection that acts on two hormone receptors, GIP and GLP-1. The FDA label approves it, with diet and exercise, for weight reduction in adults with obesity or overweight plus a weight-related condition, and for moderate to severe obstructive sleep apnea in adults with obesity. In the SURMOUNT-5 trial it produced 20.2% average weight loss at 72 weeks against 13.7% for semaglutide. Lilly sells it self-pay from $299 a month.
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Side effectsDose changeWeigh-in and resultsFood, protein and eatingFood noise and cravingsInjection techniqueCost and insuranceExercise and strengthStopping and maintenanceThe trials
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