GLP-1 TV · Patient story · views checked Oct 2026
11 MONTHS ON SEMAGLUTIDE | Weight Loss at 50 Years Old
Patient story
Our summary
Shelly, who runs the Geek Out of Water channel, gives an 11-month update on compounded semaglutide. She says she started last December at 274 lbs and now weighs 220.7 lbs, a loss of just over 53 lbs at week 45. She turned 50 that week and says she had hoped to lose 50 lbs by that birthday. She reports an average of about 1.2 lb per week, and a usual pace of 1.5 to 1.75 lb per week when things are on track. Her doctor thinks her 175 lb goal weight may be too low, but suggested they not focus on the numbers.
One person's experience, in their words. Not medical advice.
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What else the video covers
Shelly explains that she moved from a Virginia clinic, where she says she paid an average of $524 a month at the max dose, to a prescription from her regular doctor filled at a local compounding pharmacy. She says that now costs just under $350 a month for 2.5 milligrams weekly, drawn as a 100 unit dose. She says she prefers a local doctor to cheaper online options, the lowest of which she found at about $275 a month. She describes August and September as a net zero: she traveled, ate out at nearly every meal, gained 5 lbs in August, then lost them in September. She says she has been constipated recently and takes half a dose of a prebiotic and probiotic gummy, which she says helps when she also eats vegetables daily.
She also describes weeks of strong nausea that she first assumed came from semaglutide. By stopping and restarting supplements one at a time, she concluded a folate and B12 supplement was the cause. She says she is not giving medical advice. The video ends with her thoughts on loose skin, how her body looks and feels at lower weight, and her mixed feelings about being visible.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 0:37 Shelly says she started at 274 lbs last December and now weighs 220.7 lbs after 45 weeks, a loss of just over 53 lbs.
- 5:13 She says she switched to a prescription from her regular doctor through a local compounding pharmacy, paying just under $350 a month at 2.5 milligrams weekly versus an average of $524 a month before.
- 8:53 She reports gaining 5 lbs in August from travel and restaurant eating, then losing it in September, so those two months were a net zero.
- 13:30 She says she became constipated after many months without it, and that a half-dose prebiotic and probiotic gummy plus daily vegetables has helped.
- 15:35 She says weeks of heavy nausea turned out to come from a folate and B12 supplement rather than semaglutide, based on stopping and restarting each item.
- 19:44 She discusses loose skin and the changes in how her body looks and feels as she loses weight, saying she is more accepting of them than when she lost weight about 12 or 13 years ago.
Key moments
From the creator's own chapters. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- semaglutide
- Point in the journey
- Month 11
- Weight loss mentioned
- 100 lb
- Side effects mentioned
- nausea, constipation, loose skin or face changes and muscle loss
- Prices mentioned
- $524 a month
- Who is speaking
- Patient
Questions this video answers
How much weight did she lose after 11 months on compounded semaglutide?
Shelly says she went from 274 lbs to 220.7 lbs over 45 weeks, a loss of just over 53 lbs. She calculates an average of about 1.2 lb per week, and says her usual pace is 1.5 to 1.75 lb per week.
How much does compounded semaglutide cost per month in this video?
She says she paid an average of $524 a month at the max dose through a Virginia clinic. Her regular doctor's prescription through a local compounding pharmacy costs her just under $350 a month, and the cheapest online option she found was about $275 a month.
What caused her nausea on semaglutide?
Shelly says she first blamed semaglutide for hours-long nausea but later traced it to a folate and B12 supplement. She says the nausea stopped when she dropped it and returned when she tried it again, including with food.
Did she gain weight while traveling on semaglutide?
She says she gained 5 lbs in August while eating out at nearly every meal, including a day of mostly ice cream and pizza in Chicago. She says she lost the 5 lbs in September after returning to her usual eating.
Videos on the same question
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SEMAGLUTIDE: 8 MONTH UPDATE | Weight Loss at Age 49Shelly, who runs the Geek Out of Water channel, gives an 8 month update on taking compounded semaglutide.
Compound Semaglutide Weight Loss Journey || IVIM HEALTH 🩺Miss Arianna, a creator who says she is a mom and a student, shares her weight loss results after about 12 weeks on compounded semaglutide from a provider she names as IVIM Health.
4 MONTHS ON SEMAGLUTIDE | Weight Loss at Age 49Shelly, who runs the Geek Out of Water channel, describes her first 16 weeks on compounded semaglutide.
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About Geek Out of Water
Patient story, 47.7K subscribers. 5 of their videos are in GLP-1 TV, 178K views between them, mostly on Compounded semaglutide, Wegovy.
- 4 MONTHS ON SEMAGLUTIDE | Weight Loss at Age 49
- SEMAGLUTIDE: 8 MONTH UPDATE | Weight Loss at Age 49
- SEMAGLUTIDE 9 MONTH UPDATE: Results from my doctor
Read next
Our guides closest to what this video covers, with prices checked weekly.
- The best GLP-1 for weight loss, ranked by the evidence and then by the bill
By weight lost, the order is settled: tirzepatide (Zepbound) first at 20.2% in the only head-to-head, then semaglutide 7.2 mg (Wegovy HD) at 18.7%, then semaglutide 2.4 mg (Wegovy) at 13.7% to 15.6%, then the pills. By what you pay, the order nearly inverts: compounded semaglutide from $69 a month, the Wegovy tablet from $149, Wegovy pen $349, Zepbound $299 to $699 by dose. The best one is where those two lists meet for your budget and your plan.
- Tirzepatide vs semaglutide: the head-to-head result, and what the better one costs
They were finally tested against each other. In SURMOUNT-5, 751 adults with obesity took the maximum tolerated dose of one or the other for 72 weeks: tirzepatide lost 20.2% of body weight, semaglutide 13.7%. That gap is real and it is the whole argument for tirzepatide. The other half of the decision is the bill: compounded tirzepatide runs from $85 a month on our board against $69 for semaglutide, and the branded gap is wider still.
- Wegovy 7.2 mg (Wegovy HD): what the higher dose adds, and what it costs
Wegovy HD is semaglutide at 7.2 mg, three times the standard 2.4 mg dose, in its own pen. In the STEP UP trial it took 18.7% off body weight at 72 weeks against 15.6% for 2.4 mg and 3.9% for placebo, in 1,407 adults with obesity. That puts it within 1.5 points of tirzepatide's head-to-head result and makes it the strongest semaglutide there is. Novo sells it direct for $399 a month, $50 above the standard pen, and it sits above the normal ladder rather than replacing it.
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Side effectsDose changeWeigh-in and resultsInjection techniqueCost and insuranceExercise and strengthStopping and maintenanceNauseaConstipationLoose skin or face changes
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