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GLP-1 TV · Patient story · views checked Oct 2026

5 Things I Wish I Knew Before Starting a GLP-1 After Menopause | Plus Week 25 Weigh-in Update

Patient storyBobbi B. 60,585 views16:26Jul 2025

Our summary

Bobbi B., a therapist and artist who shares her GLP-1 experience on YouTube, lists five things she wishes she had known before starting a GLP-1 medication as a perimenopausal or postmenopausal woman. She says she is not a medical doctor and that none of this is medical advice. She opens with a week 25 weigh-in: she started at 210 lb, weighed 191.4 lb last week and 190.6 lb this week, for a total loss of 19.4 lb. She is 5'9" and says she averages between a half and one pound lost per week.

One person's experience, in their words. Not medical advice.

What else the video covers

The first two lessons are about eating. She says appetite and thirst suppression were stronger than she expected, and that skipping meals is tempting but risks muscle loss, bone mineral loss and fatigue. Her approach is to plan nutrient-dense, calorie-dense meals, aim for three meals a day, and keep water close. She also describes a surge in hunger around day five after her shot. She explains this using the half-lives she gives, 5 days for tirzepatide (Zepbound) and 7 days for semaglutide (Ozempic, Wegovy), and says she handles it with volume eating such as large salads or vegetable soups with protein.

The last three lessons are about support and expectations. She recommends finding a community, saying other GLP-1 users helped her learn the differences between semaglutide and tirzepatide, and that switching to Zepbound made a difference for her. She says to focus on fat loss rather than weight loss, using strength training, progress photos, a tape measure, a smart scale or a DEXA scan. Finally, she says to expect slow and steady loss, noting she has had months with no change on the scale while her clothes fit differently and she got stronger.

Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.

Takeaways

The main points, in the order they come up. Tap a time to play from there.

  1. 0:00 Bobbi reports 19.4 lb lost in 25 weeks, from 210 lb to 190.6 lb.
  2. 2:01 She says to plan for strong appetite and thirst suppression, with nutrient-dense meals, three meals a day and a water bottle at hand.
  3. 6:10 She says hunger can return around day five after a shot and suggests volume eating, such as big salads or vegetable soups with protein.
  4. 7:42 She recommends a support system, including friends, a dietitian, a therapist or an online community of GLP-1 users.
  5. 10:14 She says to track fat loss and body composition, not only weight, and calls strength training non-negotiable for menopausal women.
  6. 12:46 She says to normalize slow loss and that a plateau on the scale is not always a plateau in progress.

Key moments

From the creator's own chapters. Tap one to play from there.

  1. 0:00 Introduction and weigh-in
  2. 1:14 Managing appetite suppression
  3. 5:36 Handling appetite re-emergence
  4. 7:52 Building a support system
  5. 10:15 Focusing on fat loss
  6. 12:57 Normalizing slow progress

What the video says

As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.

Point in the journey
Week 25
Side effects mentioned
muscle loss and low appetite
Who is speaking
Patient

Questions this video answers

Why do I get hungry a few days before my next GLP-1 shot?

Bobbi says the medication level in the bloodstream is not constant, especially early on. She gives half-lives of 5 days for tirzepatide and 7 days for semaglutide, so by day five or six hunger can return. She says volume eating helps her stay in a reasonable calorie deficit.

How much weight did Bobbi lose in 25 weeks on a GLP-1?

She says she started at 210 lb and weighed 190.6 lb at week 25, a total loss of 19.4 lb. She says this is roughly a half to one pound per week on average, and that she lost 10 lb in her first month, mostly water and inflammation.

Why focus on fat loss instead of weight loss on a GLP-1 after menopause?

Bobbi says losing weight while preserving lean muscle may be slower but is better for overall health, and that faster loss can raise the risk of bone and muscle loss for menopausal women. She suggests strength training, progress photos, a tape measure, a smart scale or a DEXA scan to track body composition.

Is it normal to lose weight slowly on a GLP-1 during menopause?

She says it is common to lose about a half to two pounds per week after the initial drop, and that menopause makes weight loss slower. She reports months with no scale change while her clothes fit differently and she gained strength.

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About Bobbi B.

Patient story, 19.3K subscribers. 9 of their videos are in GLP-1 TV, 359K views between them, mostly on Zepbound.

Every Bobbi B. video

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    GLP-1 drugs such as semaglutide act on one receptor. "GLP-2" is used online for tirzepatide (Zepbound, Mounjaro), which acts on two, GIP and GLP-1, and "GLP-3" for retatrutide, which adds the glucagon receptor. Neither nickname is the real name: GLP-2 is a separate gut hormone whose drug, Gattex, treats short bowel syndrome. Retatrutide produced 28.3% mean weight loss at 80 weeks in its phase 3 trial but is not FDA-approved; Lilly plans to file in Q1 2027. Tirzepatide is the strongest option you can buy today.

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Side effectsWeigh-in and resultsFood, protein and eatingFood noise and cravingsMood and mental healthExercise and strengthMuscle lossLow appetite

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