GLP-1 TV · Patient story · views checked Oct 2026
My Honest Week 2 Update on Compounded Tirzepatide | What Changed
Our summary
In this week two update, Heather describes her experience taking compounded tirzepatide through LLYMD. She says this is her third time on GLP-1 medications in roughly two years, and that she previously used a name-brand drug and semaglutide. She reports low energy all week, no workouts, and an unsettled stomach, which she links possibly to eating more salads than usual and to a Chinese food dinner.
One person's experience, in their words. Not medical advice.
Where tirzepatide costs least today
The three cheapest partner programs for tirzepatide, all in per month, checked weekly.
What else the video covers
She says injection night brings back a side effect she remembers from before: very light, restless sleep, which she compares to having caffeine too late. She injects at night because she read online that this avoids daytime nausea, and she asks viewers who inject in the morning to comment on whether it changes things. She also says she has noticed less food noise and is eating less, though she adds that she may just be paying more attention to it.
On weight, she says she started this round at 180.0 pounds, was just under 180 last week, and is now at 178.2 pounds. She attributes the drop to eating less, and possibly water weight or inflammation, and says her clothes do not fit differently yet. She describes herself as a slow loser. Her goal for next week is to track protein and reach 100 g per day, since she wonders whether low intake explains her tiredness. She plans to post twice a week, asks viewers for topic ideas, and notes her husband is a pharmacist while stressing that she is not a doctor and viewers should check with their health care provider.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 0:00 Heather says this is her third time on GLP-1s and that she is now on compounded tirzepatide through LLYMD.
- 0:31 She reports very low energy, no workouts, and an unsettled stomach during week two.
- 1:33 She says injection night, which she does in the evening, brings her worst sleep of the week, a light and restless sleep she also noticed on earlier medications.
- 3:36 She reports going from 180.0 pounds at the start to 178.2 pounds this week, about a pound down from last week.
- 4:38 She plans to track her protein and aim for 100 g per day next week, wondering if low intake explains her fatigue.
- 5:08 She says she wants to post twice a week and reminds viewers to check with their health care provider.
Key moments
From the creator's own chapters. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- tirzepatide
- Point in the journey
- Week 2
- Side effects mentioned
- nausea and fatigue
- Who is speaking
- Patient
Questions this video answers
What side effects did she have in week 2 of compounded tirzepatide?
Heather says she had low energy, an unsettled stomach, and poor sleep on injection night. She says she has not worked out all week, and she is unsure whether the stomach issues come from eating more salads or from a Chinese food dinner.
How much weight did she lose after two weeks on compounded tirzepatide?
She says she started at 180.0 pounds and weighed 178.2 pounds at week two, about a pound lower than the previous week. She says she is a slow loser and is comfortable with that pace.
Why does she inject tirzepatide at night?
Heather says she read online, before starting two years ago, that injecting at night helps you skip most nausea. She says it has always been her routine, though she now wonders whether morning injections might help with the poor sleep.
What is her protein goal on tirzepatide?
She says she wants to track her protein next week and reach 100 g every day. She wonders whether not eating enough protein is behind her tiredness and lack of energy to exercise.
Videos on the same question
The closest videos in the library by what is said in them, not by title.
My Honest Week 3 Update on Compounded Tirzepatide | What ChangedIn this week three update, Heather says she is using compounded tirzepatide through ELMD and restarting GLP-1 treatment for the third time.
I Moved Up to 5mg on Tirzepatide… I Wasn’t Ready for THIS 😳 (Week 5 Update)In this week 5 update, Heather says she has moved up to 5 mg of compounded tirzepatide, which she gets from LEMD.
Week 1 on Compounded Tirzepatide: Side Effects, Appetite & Real ResultsIn this week 1 update, Heather says she started compounded tirzepatide at 180 lb and weighed 179.2 lb on the morning she recorded the video.
How I Weaned Off My GLP-1 | Tirzepatide Weight Loss And MaintenanceMadison Shari describes how she stopped taking compounded tirzepatide after six months.
My 1-Month Update on Compounded Tirzepatide | Brutally Honest & REAL ADVICENelly Jane gives an update on her weight loss with compounded tirzepatide.
MOUNJARO UPDATE: Anxiety, Tirzepatide order, answering questions!In this weekly Mounjaro update, Brittany Rose says she started the morning in a low mood and went for a walk, which she reports was about 7,200 steps and left her feeling much better.
About Heather's Health Journey
Patient story, 9.4K subscribers. 8 of their videos are in GLP-1 TV, 290K views between them, mostly on Compounded tirzepatide.
- How I Prep the Day Before My GLP-1 Shot to Avoid Side Effects (Nausea, Fatigue, GI Issues)
- I Moved Up to 5mg on Tirzepatide… I Wasn’t Ready for THIS 😳 (Week 5 Update)
- Compounded Tirzepatide Injection Routine in 2026 | GLP-1 Prep, Timing & Tips
Read next
Our guides closest to what this video covers, with prices checked weekly.
- Tirzepatide vs semaglutide: the head-to-head result, and what the better one costs
They were finally tested against each other. In SURMOUNT-5, 751 adults with obesity took the maximum tolerated dose of one or the other for 72 weeks: tirzepatide lost 20.2% of body weight, semaglutide 13.7%. That gap is real and it is the whole argument for tirzepatide. The other half of the decision is the bill: compounded tirzepatide runs from $85 a month on our board against $69 for semaglutide, and the branded gap is wider still.
- The best GLP-1 for weight loss, ranked by the evidence and then by the bill
By weight lost, the order is settled: tirzepatide (Zepbound) first at 20.2% in the only head-to-head, then semaglutide 7.2 mg (Wegovy HD) at 18.7%, then semaglutide 2.4 mg (Wegovy) at 13.7% to 15.6%, then the pills. By what you pay, the order nearly inverts: compounded semaglutide from $69 a month, the Wegovy tablet from $149, Wegovy pen $349, Zepbound $299 to $699 by dose. The best one is where those two lists meet for your budget and your plan.
- Retatrutide: up to 28.3% weight loss in trials, no FDA approval yet, and no legal way to buy it today
Retatrutide is Eli Lilly's experimental weekly injection that acts on three hormone receptors (GIP, GLP-1 and glucagon). In the phase 3 TRIUMPH-1 trial, people on the 12 mg dose lost 28.3% of their weight at 80 weeks by Lilly's efficacy measure (25.0% counting everyone randomized). It is not FDA-approved, has no price, and cannot legally be sold. Lilly plans to file with FDA in Q1 2027. Tirzepatide is the closest thing you can buy now, compounded from $85 a month on our board.
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