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GLP-1 TV · Patient story · views checked Oct 2026

I started Tirzepatide! Weight loss medication, Week 1, How much I lost, symptoms & more!

Patient storyThe Fasho Life39,772 views20:01Dec 2024

Our summary

Tiffany, who runs The Fasho Life channel, describes her first week on tirzepatide, which she says she has taken for less than two weeks. She explains that she has struggled with weight loss for about six years, lost around 50 lbs on keto in 2018, regained it, and has lost 40 lb since giving birth plus another 6 lb before starting the medication. She says the drug was offered to her through a company outreach, and she describes it as a GLP-1 medication that suppresses appetite, slows gastric emptying and lowers A1C.

One person's experience, in their words. Not medical advice.

What else the video covers

For week one she says she started at 2.5 mg, which she believes is 25 units. She reports slightly reduced appetite overall, with the biggest change being far less late-night snacking and fewer cravings after dinner. On side effects, she says she had some nausea but did not need the Zofran she was prescribed. After eating fried homemade egg rolls on day three, she had diarrhea the next day, and she concludes greasy food does not agree with the medication. She also had mild constipation on days five and six without using a laxative. She is not eating low carb, but is eating smaller portions of family meals.

A middle section is sponsored by Hume Health and promotes its Body Pod body analyzer, including a discount code. For results, she says she went from 291 lbs to 284.5 lbs, a loss of 6.6 lbs in the first week, which she notes took her roughly a month and a half to two months to lose before. She becomes emotional discussing it, says she does not expect that pace every week, and adds that she feels less puffy and bloated. She plans to track body composition rather than only the scale and to keep updating viewers.

Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.

Takeaways

The main points, in the order they come up. Tap a time to play from there.

  1. 2:03 She says tirzepatide suppresses appetite, delays gastric emptying and lowers A1C, and that she views it as slightly different from another medication she plans to cover separately.
  2. 4:10 She started at 2.5 mg, which she believes is 25 units, and noticed mainly less late-night snacking and fewer cravings.
  3. 6:16 She reports nausea she did not treat, diarrhea after fried egg rolls, and mild constipation on days five and six.
  4. 10:30 She says she uses a Hume Health body analyzer in a sponsored segment to track more than scale weight.
  5. 13:55 She reports going from 291 lbs to 284.5 lbs, a 6.6 lb loss in week one, and says she does not expect that every week.
  6. 16:43 She says she feels less puffy and bloated and plans to focus on body composition going forward.

Key moments

From the creator's own chapters. Tap one to play from there.

  1. 0:00 My weight loss journey
  2. 1:07 Starting tirzepatide
  3. 2:32 How the medication works
  4. 3:47 First week experience
  5. 6:03 Managing side effects
  6. 9:33 Body composition tracking
  7. 14:04 Weight loss results
  8. 16:42 Future goals and depuffing

What the video says

As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.

Medication
tirzepatide
Doses mentioned
2.5 mg
Point in the journey
Week 1
Weight loss mentioned
6.6 lb
Side effects mentioned
nausea, constipation and muscle loss
Who is speaking
Patient

Questions this video answers

How much weight did she lose in the first week on tirzepatide?

Tiffany says she went from 291 lbs to 284.5 lbs, a loss of 6.6 lbs in week one. She notes that this amount previously took her about a month and a half to two months, and that she does not expect the same pace every week.

What dose of tirzepatide do you start on?

Tiffany says she started at 2.5 mg, which she believes is 25 units. She says doses are typically increased month by month as the body adjusts.

What side effects did she have in week one of tirzepatide?

She reports some nausea that did not require her prescribed Zofran, diarrhea the day after eating fried egg rolls, and mild constipation on days five and six. She says she needed no laxative and that everyone's body is different.

Did tirzepatide reduce late-night snacking?

Tiffany says it did. She reports that after dinner she stopped thinking about dessert or snacks while up late, which she says normally happened when she stayed up past 10 or 11.

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  • GLP-1 vs GLP-2 vs GLP-3: what the names mean, and which ones you can actually buy

    GLP-1 drugs such as semaglutide act on one receptor. "GLP-2" is used online for tirzepatide (Zepbound, Mounjaro), which acts on two, GIP and GLP-1, and "GLP-3" for retatrutide, which adds the glucagon receptor. Neither nickname is the real name: GLP-2 is a separate gut hormone whose drug, Gattex, treats short bowel syndrome. Retatrutide produced 28.3% mean weight loss at 80 weeks in its phase 3 trial but is not FDA-approved; Lilly plans to file in Q1 2027. Tirzepatide is the strongest option you can buy today.

  • Retatrutide: up to 28.3% weight loss in trials, no FDA approval yet, and no legal way to buy it today

    Retatrutide is Eli Lilly's experimental weekly injection that acts on three hormone receptors (GIP, GLP-1 and glucagon). In the phase 3 TRIUMPH-1 trial, people on the 12 mg dose lost 28.3% of their weight at 80 weeks by Lilly's efficacy measure (25.0% counting everyone randomized). It is not FDA-approved, has no price, and cannot legally be sold. Lilly plans to file with FDA in Q1 2027. Tirzepatide is the closest thing you can buy now, compounded from $85 a month on our board.

  • Tirzepatide vs semaglutide: the head-to-head result, and what the better one costs

    They were finally tested against each other. In SURMOUNT-5, 751 adults with obesity took the maximum tolerated dose of one or the other for 72 weeks: tirzepatide lost 20.2% of body weight, semaglutide 13.7%. That gap is real and it is the whole argument for tirzepatide. The other half of the decision is the bill: compounded tirzepatide runs from $85 a month on our board against $69 for semaglutide, and the branded gap is wider still.

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