GLP-1 TV · Patient story · views checked Oct 2026
Compounded Semaglutide | Week 1 & 2 Update | Weight Loss
Our summary
In this update, the creator describes her first two weeks on compounded semaglutide at 10 units, recorded right after her third injection. She says she lost 9.8 pounds in that time, more than she has ever lost in two weeks, and she expects part of it to be water weight. She also says she feels less bloated and has lost a couple of inches.
One person's experience, in their words. Not medical advice.
Where semaglutide costs least today
The three cheapest partner programs for semaglutide, all in per month, checked weekly.
What else the video covers
She walks through how appetite changed across each week. Her first shot was at 10:30 in the morning, and she says she did not notice appetite suppression until about 6:30 that evening. For roughly the first three to four days after each shot she felt almost no hunger, and the thought of food made her queasy, so she ate very small, high protein portions several times a day. Hunger returned gradually, and she says she was hungriest on the sixth and seventh days of each week. Even then she says she gets full quickly and eats far less than she used to.
She reports no major side effects beyond the queasiness early in each cycle. She says she has had no headaches, no trouble in the restroom and no vomiting, and she drinks electrolytes and high protein shakes. She calls the injections painless. Her fifth shot would normally move up to 15 units, but she says that if her results stay strong she plans to ask her provider whether she needs to increase at all, and she will post a follow-up once she decides between 10 and 15 units.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 0:45 She says her first shot was at 10:30 in the morning and appetite suppression only began around 6:30 that evening.
- 1:48 She reports almost no hunger for the first three to four days after a shot, which led her to eat tiny, high protein meals.
- 2:50 According to her, hunger slowly returned and was strongest on the sixth and seventh days, though she still got full very quickly.
- 4:23 She reports losing 9.8 pounds in two weeks and expects some of it to be water weight.
- 5:26 She says she has had no headaches, restroom problems or vomiting, only early queasiness, and she drinks electrolytes and protein shakes.
- 6:26 She plans to ask her provider whether she needs to move up to 15 units or can stay at 10 units, and will post an update.
Key moments
From the creator's own chapters. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- semaglutide
- Point in the journey
- Week 1
- Side effects mentioned
- nausea and low appetite
- Who is speaking
- Patient
Questions this video answers
How much weight can you lose in the first two weeks of compounded semaglutide?
The creator says she lost 9.8 pounds in her first two weeks on 10 units of compounded semaglutide. She says it was the most she has ever lost in two weeks and that she expects a good share to be water weight.
How long does it take for compounded semaglutide to suppress appetite?
She says she first noticed appetite suppression about eight hours after her first injection, around 6:30 in the evening after a 10:30 morning shot. She reports almost no hunger for the first three to four days after each shot.
What side effects did she have in the first two weeks of compounded semaglutide?
She reports queasiness at the thought of food in the first few days after each shot, and no major side effects beyond that. She says she had no headaches, no restroom issues and no vomiting, and that the injections were painless.
Does she increase from 10 units to 15 units of semaglutide?
She says her fifth shot would normally start 15 units, but she plans to contact her provider and may stay at 10 units if her results remain good. She says she will post an update once she decides.
Videos on the same question
The closest videos in the library by what is said in them, not by title.
SEMAGLUTIDE SERIES | EPISODE 3 | MY FIRST 8 WEEKS EXPERIENCESarah Taylor, a creator posting a semaglutide series, covers her first eight weeks on semaglutide.
First Week On SemaglutideIn this update, Lauren Brazee says she is a little over a week into semaglutide, following her first-shot video.
Compound Semaglutide Weight Loss Journey || IVIM HEALTH 🩺Miss Arianna, a creator who says she is a mom and a student, shares her weight loss results after about 12 weeks on compounded semaglutide from a provider she names as IVIM Health.
SEMAGLUTIDE JOURNEY *week 2* // Food guilt (let's talk about it), finding balance + down 8 lbs!In this week two update, the creator says she is on her second week of semaglutide and takes her second shot on Friday, October 11 at 9:15 in the morning, again in the stomach.
Upped my Semaglutide (Glp1) maintenance dose only 5 units! Did it make me sick?Karli Sine says she had been taking a steady 15 units of semaglutide as her maintenance dose.
Wegovy Weight Loss Transformation | My first Semaglutide Compound DoseMindy Pedersen, a creator who posts weekly updates on her weight loss, says this video covers her first week on a compounded semaglutide sublingual tablet after 24 weeks of Wegovy injections.
Read next
Our guides closest to what this video covers, with prices checked weekly.
- Semaglutide side effects, and what compounding does and does not change
Semaglutide's side effects are gastrointestinal: nausea, vomiting, diarrhoea and constipation, worst early and after each dose increase. Those belong to the molecule, so they are the same whether it came in a Novo Nordisk pen or a compounding pharmacy's vial. What compounding changes is everything around the molecule. A compounded drug is not FDA-approved, so the finished product has not been reviewed for safety, effectiveness or manufacturing quality, and the FDA has said the enforcement discretion that allowed 503A pharmacies to compound semaglutide has ended. It also usually arrives as a vial and a syringe rather than a pre-set pen, which moves dose measurement to you.
- Semaglutide for weight loss: which version, and what each costs
Semaglutide is the molecule. For weight loss the FDA-approved version is Wegovy, sold as a weekly pen and a daily tablet. Ozempic is the same molecule approved for type 2 diabetes, so using it for weight is off-label. Compounded semaglutide is the same molecule from a compounding pharmacy, is not FDA-approved, and is what most cash buyers actually take because it costs a fraction of the brand. All three produce the same side effects. What differs is the approval, the oversight and the price.
- Stopping a GLP-1: what the withdrawal trials found, and what a maintenance dose actually is
Two trials have measured what happens when you stop. On semaglutide, people who lost 17.3% over 68 weeks regained two-thirds of it in the year after stopping, ending 5.6% below where they started. On tirzepatide, people who lost 20.9% in 36 weeks regained 14% over the next year on placebo while those who continued lost a further 5.5%. Both labels are explicit that these drugs are for maintaining weight reduction long term, which is a different claim from finishing a course. A maintenance dose is simply the dose you stay on; the labels do not define a lower one to step down to at goal.
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