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GLP-1 TV · Patient story · views checked Oct 2026

First Week On Semaglutide

Patient storyLauren Brazee22,078 views8:56Jan 2024

Our summary

In this update, Lauren Brazee says she is a little over a week into semaglutide, following her first-shot video. She reports a 7 lb drop on the scale that morning and says she has not taken a second shot yet. She still has three shots left, does not feel hungry, and says cravings are not bad. She plans to take the next one on Monday and says she is stretching doses partly because she pays for the medication monthly. She films while making a four-ingredient bread dough.

One person's experience, in their words. Not medical advice.

What else the video covers

She describes her side effects as minimal. About 8 hours after the first shot she had one wave of nausea that she compares to morning sickness, and it passed. She says the constant thoughts about meals and treats, which she calls food noise, stopped right away. For nausea she says she uses a CBD product, which helped her avoid Zofran. She says she lost 4 lbs of water weight on day one and that she tends to lose water weight quickly because of insulin resistance. She also says she had a similar drop after quitting alcohol.

Lauren says she plans to stay on the lowest dose as long as possible and does not mind losing more slowly if she feels fine. She says her blood sugar has been good. She stresses that the 7 lbs is mostly inflammation and water, not fat, and that results differ by person. She says she also exercises daily, drinks plenty of water, eats over 125 grams of protein a day, and suggests a 20 to 30 minute daily walk. She encourages anyone who sees no results to keep trying other approaches.

Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.

Takeaways

The main points, in the order they come up. Tap a time to play from there.

  1. 0:31 She reports losing 7 lbs in a little over a week on semaglutide and says she has not yet taken a second shot.
  2. 1:33 About 8 hours after her first shot she had a brief wave of nausea, and she says her food noise stopped right away.
  3. 3:39 She says 4 lbs of the loss came as water weight on day one and links fast water loss to her insulin resistance.
  4. 5:41 She says she plans to stay on the lowest dose as long as possible and reports no side effects beyond that one nausea episode.
  5. 6:41 She says the 7 lbs is mostly inflammation, not fat, and that she uses a CBD product for nausea instead of Zofran.
  6. 7:47 She says she also exercises daily, drinks lots of water, eats over 125 grams of protein a day, and suggests walking 20 to 30 minutes.

Key moments

From the creator's own chapters. Tap one to play from there.

  1. 0:00 Semaglutide update
  2. 0:37 Weight loss results
  3. 1:13 Homemade bread recipe
  4. 1:47 Managing side effects
  5. 2:11 Food noise and habits
  6. 4:22 Final dough preparation
  7. 5:13 Health journey advice
  8. 7:13 Encouragement to viewers

What the video says

As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.

Medication
semaglutide
Point in the journey
Week 1
Weight loss mentioned
7 lb
Side effects mentioned
nausea
Who is speaking
Patient

Questions this video answers

How much weight did she lose in the first week on semaglutide?

Lauren says she lost 7 lbs in a little over a week, including 4 lbs of water weight on the first day. She says she does not consider it fat loss, describing it as mostly inflammation.

What side effects did she have in the first week of semaglutide?

She says she had one wave of nausea about 8 hours after her first shot, which felt like morning sickness and passed. She reports no other side effects and no food aversions.

What is food noise on semaglutide?

Lauren describes food noise as constant, overwhelming thoughts about the next meal, treat or dessert. She says it stopped immediately after her first shot.

How does she handle nausea on semaglutide?

She says she takes a CBD product when nauseous, which she says helped her avoid needing Zofran. She notes this is what works for her.

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Read next

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  • Semaglutide side effects, and what compounding does and does not change

    Semaglutide's side effects are gastrointestinal: nausea, vomiting, diarrhoea and constipation, worst early and after each dose increase. Those belong to the molecule, so they are the same whether it came in a Novo Nordisk pen or a compounding pharmacy's vial. What compounding changes is everything around the molecule. A compounded drug is not FDA-approved, so the finished product has not been reviewed for safety, effectiveness or manufacturing quality, and the FDA has said the enforcement discretion that allowed 503A pharmacies to compound semaglutide has ended. It also usually arrives as a vial and a syringe rather than a pre-set pen, which moves dose measurement to you.

  • Tirzepatide vs semaglutide: the head-to-head result, and what the better one costs

    They were finally tested against each other. In SURMOUNT-5, 751 adults with obesity took the maximum tolerated dose of one or the other for 72 weeks: tirzepatide lost 20.2% of body weight, semaglutide 13.7%. That gap is real and it is the whole argument for tirzepatide. The other half of the decision is the bill: compounded tirzepatide runs from $85 a month on our board against $69 for semaglutide, and the branded gap is wider still.

  • Zepbound side effects: the label's table by dose, who actually quits, and how it compares to semaglutide

    Zepbound's label puts a number on every common side effect at each of its three maintenance doses. Nausea runs 25 to 29 percent against 8 on placebo, diarrhoea 19 to 23, vomiting 8 to 13, constipation 11 to 17. Across the two approval trials, 4.8 to 6.7 percent of people stopped the drug because of side effects, against 3.4 percent on placebo, and most of those who quit did so in the first months, from gut effects during dose escalation. Below that table are the rarer things the label warns about, with the trial rates where it gives them, and the honest comparison to Ozempic's table.

Find more like it

Side effectsWeigh-in and resultsFood, protein and eatingFood noise and cravingsExercise and strengthAlcoholStopping and maintenanceHow it worksNausea

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