The rest of the deal
| ShedRx | Direct Meds GLP-1 | |
|---|---|---|
| Lowest price, all in | $159/mosemaglutide injection, compounded, 12-month plan, $1,908 up front | $249/mosemaglutide, oral, compounded, billed monthly |
| Month to month | $199/mofrom, semaglutide injection, compounded | $249/mofrom, semaglutide, oral, compounded |
| Membership fee | None | None |
| Consultation | Included | Included |
| What it sells |
|
|
| Oral option | Yes, priced on request | Semaglutide, oral, compounded |
| Brand-name drugs | Yes | No, compounded only |
| Insurance | Cash only | Cash only |
| States served | All 50 states | Not in Arkansas |
| Shipping | Included | Included |
| Cancellation | Cancel anytime | Cancel anytime |
| Clinicians | Licensed doctors alongside health coaching and supplement advice | Licensed clinicians |
| Price by dose | No dose-level prices published, so no per-mg figure | No dose-level prices published, so no per-mg figure |
| Trustpilot | 4.7 of 51,126 reviews on Trustpilot | 4.6 of 514,673 reviews on Trustpilot |
| Prices last read | October 2026 | October 2026 |
Ratings are shown as published and never change our order, which is by price only. We do not print a cost per 1% of weight lost: the published trials measured brand-name drugs, not these programs’ compounded versions, so the figure would borrow a result neither product earned.
Who each one fits
Pick ShedRx if
- you want the lower semaglutide price: $159 a month on a 12-month plan, against $297 at Direct Meds GLP-1
- you want compounded tirzepatide, which Direct Meds GLP-1 does not sell
- you want to pay month to month: from $199, against $249
- you want a GLP-1 you do not inject
- you want an FDA-approved brand drug
- you live in Arkansas, where Direct Meds GLP-1 does not ship
Pick Direct Meds GLP-1 if
- you want its lowest price without prepaying (ShedRx's lowest needs 12 months up front)
What each includes, and the catch
ShedRx
- Consultation: included
- Shipping: included
- Membership: none
- Cancel anytime
Worth knowing
- Cost rises as your dose grows, reaching as much as $299/mo
- Support feedback is uneven, and reply times can drag
Direct Meds GLP-1
- Consultation: included
- Shipping: included
- Membership: none
- Cancel anytime
Worth knowing
- Carries compounded formulas only, not FDA-approved brand drugs
- A lesser-known name with a thinner online review trail
Every Direct Meds GLP-1 price and review · Is Direct Meds GLP-1 legit?
Common questions
Which is cheaper, ShedRx or Direct Meds GLP-1?
ShedRx is cheaper than Direct Meds GLP-1 on every plan both sell (1 like-for-like price compared). The lowest price at ShedRx is $159 a month on a 12-month plan ($1,908 up front); at Direct Meds GLP-1 it is $249 a month month to month. Both all in, membership fees included.
Do ShedRx or Direct Meds GLP-1 charge a membership fee?
ShedRx: none. Direct Meds GLP-1: none. Read from each program's own site; the prices on this page already include any fee.
Can I pay month to month at ShedRx and Direct Meds GLP-1?
ShedRx publishes a month-to-month price from $199. Direct Meds GLP-1 publishes a month-to-month price from $249.
Do ShedRx and Direct Meds GLP-1 take insurance?
ShedRx is cash only; Direct Meds GLP-1 is cash only. Every price here is the cash price.
Which states do ShedRx and Direct Meds GLP-1 serve?
ShedRx: all 50 states. Direct Meds GLP-1: not in arkansas.
Do ShedRx or Direct Meds GLP-1 sell tirzepatide or a pill?
ShedRx sells semaglutide injection, compounded; tirzepatide injection, compounded. Direct Meds GLP-1 sells semaglutide, oral, compounded; semaglutide injection, compounded.
How are ShedRx and Direct Meds GLP-1 rated on Trustpilot?
ShedRx: 4.7 of 5 from 1,126 reviews. Direct Meds GLP-1: 4.6 of 5 from 14,673 reviews. Ratings never change our order, which is by price.
Where these numbers come from
- ShedRx · read October 2026
- Direct Meds GLP-1 · read October 2026
Check both prices
Prices change. Each button opens the program’s own site, where the price you see at checkout is the one that counts.