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GLP-1 TV · News & media · views checked Oct 2026

Does GLP-1 Microdosing Work? Noom CEO Responds

News & mediaOn The Pen™ GLP-1 News3,993 views42:23Aug 2025

Our summary

In this interview on the On the Pen podcast, host Dave Napman talks with Jeff Cook, who the host introduces as the CEO of Noom. Cook first describes attending a White House event where Noom signed a pledge, led by CMS, on health data portability and access. He says the aim is to end the silos where providers hold separate records, that patients must opt in to any data exchange, and that people can see who accessed their data.

General education as published by the channel. Not medical advice, and not an endorsement.

What else the video covers

The main topic is Noom's new microdose GLP-1 program, which Cook says officially launched on August 4. He explains that Noom defines a microdose as 25% of the high maintenance dose, since the term has no standard definition. According to Cook, more than 70% of people on this program report no side effects while still losing 5 to 10 percent of body weight. He gives program prices of $119 for the first month and $199 after that, compared with $149 and $279 for Noom's regular GLP-1Rx program. He cites a New England Journal of Medicine study in which, he says, 5 milligrams drove 72% of the weight loss seen at 15 milligrams. He says the program covers semaglutide up to a stated limit and is for people with a BMI of 25 or higher. He also describes his own microdosing and says he thinks lower-BMI use is where the field is heading, though Noom is not there yet.

The two also discuss why trial dropout rates may not reflect real-world use, how Noom aims for the lowest dose that meets a person's goal, and Noom's taper protocol. Cook says few people use the taper option. Napman adds his own views, which are separate from Cook's claims.

Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.

Takeaways

The main points, in the order they come up. Tap a time to play from there.

  1. 1:35 Cook says Noom signed a CMS-led pledge at the White House on health data portability and access, with patient opt-in and visibility into who accesses their data.
  2. 12:38 Cook explains that Noom's microdose GLP-1 program is meant to address side effects and cost.
  3. 14:34 Cook says Noom defines a microdose as 25% of the high maintenance dose and reports that over 70% of users have no side effects with 5 to 10 percent weight loss.
  4. 16:36 Cook cites a New England Journal of Medicine study in which, he says, 5 milligrams produced 72% of the weight loss seen at 15 milligrams.
  5. 22:24 Cook says Noom aims for the lowest dose that reaches a person's goal, using member logs of weight and side effects to adjust the dose.
  6. 37:37 Cook says Noom's taper protocol is used by a small share of people, and the program shifts toward caloric restriction when it is activated.

Key moments

From the creator's own chapters. Tap one to play from there.

  1. 0:00 Introduction to Noom
  2. 1:26 White House data pledge
  3. 7:25 Modernizing health records
  4. 12:12 Microdosing GLP-1 program
  5. 18:29 Clinical studies vs real world
  6. 25:13 Data-driven habit building
  7. 30:48 Future of GLP-1 treatments
  8. 36:20 Tapering protocols

What the video says

As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.

Doses mentioned
2.4 mg, 5 mg and 15 mg
Who is speaking
News or media

Questions this video answers

How does Noom define a microdose of GLP-1?

Cook says there is no well-defined industry term, so Noom defines a microdose as 25% of the high maintenance dose. He adds that the program starts below the lowest commercial dose and goes up to that 25% level.

How much does the Noom GLP-1 microdose program cost?

According to Cook, the microdose program costs $119 for the first month and $199 after that. He compares this with $149 and $279 for Noom's GLP-1Rx program.

Who can use Noom's microdose GLP-1 program?

Cook says the program is currently available only to people with a BMI of 25 or higher. He says he expects lower-BMI use to be where the field goes, but that Noom is not there yet.

Does Noom offer a tapering protocol for GLP-1 medication?

Cook says Noom has a taper protocol that supports tapering down or off, and that it can be used with the GLP-1 companion product. He says only a small share of people activate it, and the program then focuses more on caloric restriction.

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About On The Pen™ GLP-1 News

News & media, 37.5K subscribers. 41 of their videos are in GLP-1 TV, 468K views between them, mostly on Zepbound, Compounded tirzepatide, Mounjaro.

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Read next

Our guides closest to what this video covers, with prices checked weekly.

  • Is Noom legit? What Noom's GLP-1 program costs, its reviews, and its record

    Yes. Noom is a real company, and its Noom Med arm prescribes GLP-1s through licensed clinicians. As of October 2026 its own site prices the medication-included Noom GLP-1Rx plan, which is compounded semaglutide, at $129 for the first four weeks, then $279 a month billed as $837 every 12 weeks, though the FAQ on the same page says $249. Trustpilot scores Noom 4.5 across 67,088 reviews, mostly about its app, and we found no FDA warning letter naming it.

  • Microdosing GLP-1s: what it saves you, and what it doesn't

    Microdosing a GLP-1 does not save money at a compounded seller: none of the compounded programs we track charges less for a smaller dose. Microdosing is not a medical term, and no dose below the label's starting dose has been studied for this. The one microdosing product on our board costs more a month than full-dose compounded tirzepatide at the cheapest seller we track. Where dose really moves the price is the brands; the provider table, per-mg costs and live numbers are below.

  • GLP-1 patient assistance programs: what Lilly Cares and Novo's PAP actually cover

    Both makers run free-drug programs for people with low income and no insurance or Medicare, but neither covers its weight-loss GLP-1. Novo Nordisk's Patient Assistance Program supplies Ozempic injections free to uninsured patients at or below 200% of the federal poverty level, and lists no Wegovy and no pills. Lilly Cares lists Trulicity as its only GLP-1: no Mounjaro, no Zepbound, no Foundayo. For weight loss, the realistic low-cost routes are the Medicare GLP-1 Bridge at $50 a month and the cash market.

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