PriceTracker GLP-1
Explainers12:19

GLP-1 TV · Clinician · views checked Oct 2026

Pros & cons of GLP-1 weight loss drugs | Dr. Ralph DeFronzo

ClinicianPeter Attia MD185,298 views12:19Mar 2025

Our summary

A clinician (MD) explains how semaglutide works and what the evidence says. Side effects mentioned: muscle loss. Also covers exercise and strength and the trials.

PlayYouTube

General education as published by the channel. Not medical advice, and not an endorsement.

Key moments

From the creator's own chapters. Tap one to play from there.

  1. 0:00 Safety and the pipeline
  2. 0:37 Weight loss and muscle mass
  3. 2:17 Functional gains in strength
  4. 4:35 Myostatin inhibitors
  5. 6:42 Clinical trial criteria
  6. 8:39 Redefining functional tests
  7. 9:39 Pharmacological vs exercise

What the video says

As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.

Medication
semaglutide
Side effects mentioned
muscle loss
Who is speaking
Clinician, MD

Find more like it

GLP-1 explained

Dose changeExercise and strengthHow it worksThe trialsMuscle loss

Up next

More from this collection

24:48What Happens When You Stop ‘Skinny Jabs’? | BBC NewsBBC NewsNews & media2.3M viewsJan 2026
6:50What is GLP-1 & How Does It Reduce Appetite & Promote Weight Loss? | Dr. Andrew HubermanHuberman Lab ClipsNews & media531K viewsJul 2022
22:45GLP-1: Science and Hacks You MUST KnowGlucose RevolutionPatient story425K viewsFeb 2025
1:31:27The Doctor Who Took Weight Loss Medication | Dr. Christle GuevarraDoctor MikeClinician408K viewsNov 2025
20:295 Things Your Doctor Should Be Telling You About GLP-1sAjenda by Dr. Jen AshtonClinician325K viewsApr 2026
12:37How do GLP-1 Agonists Work? (EASY Pharmacology)Drug ChugClinician291K viewsApr 2025
25:22GLP-1 Newbies: Tips You Need to Knowsmall things dailyPatient story280K viewsSep 2025
9:05You Don't Know What Tirzepatide is Doing to Your Body (Dr Explains)Dr. Kevin Joseph, DOClinician262K viewsAug 2026
4:38How does sitagliptin work? DPP-4 inhibitors and GLP-1 mimeticsZero To FinalsClinician232K viewsDec 2016
19:45Not Losing Weight on GLP-1? My Doctor Finally Explained WhySlow & Steady with AndiPatient story201K viewsApr 2026
42:13Tirzepatide + Metabolic Health: What the Latest Study Really Shows | Solo EP. 207Dr. Tyna MooreClinician166K viewsApr 2025
1:27What is a GLP-1 agonist, and how does it work? | Ohio State Medical CenterOhio State Wexner Medical CenterClinician158K viewsDec 2024
10:37Obesity Medicine Doctor Explains: 12 GLP-1 Foods You Should Always Have at HomeBazgha Khalid, MDClinician147K viewsSep 2026
11:16How To Lose Weight On Tirzepatide (Doctor Who Takes It)Dr. Lee MD | Obesity & TelemedicineClinician123K viewsAug 2026
7:23Weight Loss Takes How Long on GLP-1? Obesity DoctorWeight Medicine with Dr. Meghan MDClinician117K viewsSep 2024
47:5242: What is GLP-1, What Does It Do, and Where Does It Come From with Dr. Ben BikmanBen BikmanPatient story108K viewsFeb 2024

Watched it? See what it costs.

Every GLP-1 program we track, ranked by what actually leaves your account.

Back to GLP-1 TV