GLP-1 TV · Patient story · views checked Oct 2026
Week 1 on Compounded Tirzepatide: Side Effects, Appetite & Real Results
Patient story
Our summary
In this week 1 update, Heather says she started compounded tirzepatide at 180 lb and weighed 179.2 lb on the morning she recorded the video. She describes herself as a slow loser and says she did not expect fast results. Her goal for the week was to watch for symptoms and side effects, since she has used brand name Zepbound before but this is her first time on the compounded version. She notes that the first month is a loading dose and that, as she understands it, therapeutic doses come at the second or third month at the earliest.
One person's experience, in their words. Not medical advice.
Where tirzepatide costs least today
The three cheapest partner programs for tirzepatide, all in per month, checked weekly.
What else the video covers
She says she injects at night and lets the medication sit on the bathroom counter while she gets ready for bed, which takes the chill off. This week the injection stung, which she attributes to her own mistake: she believes she went through a stretch mark while feeling jittery about filming it for social media. She says to pick clear skin without stretch marks, scarring or wounds. She reports very minimal side effects, some mild fatigue that she links to her period, two toddlers and a full-time job rather than the medication, and less thinking about food. She also says she was not perfect with eating, mentioning ice cream and Valentine's Day sweets.
Heather describes other changes: a morning protein shake with coffee, smaller portions, giving up her usual weekly can of soda because of concerns about carbonation and digestion, and restarting weight training. Her plan is dumbbell strength work three days a week and treadmill walking with a weighted vest two days a week. She also says her order from LEMD arrived two days after she placed it, and that it included needles, alcohol swabs and five anti-nausea pills. She closes by saying week 1 is about managing expectations and observing the body.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 0:00 Heather says she began at 180 lb and weighed 179.2 lb after the first week, and she expected slow results.
- 1:02 She explains her understanding that the first month is a loading dose and therapeutic doses come at month two or three at the earliest.
- 1:45 She describes injecting at night after letting the medication warm slightly, and says this week's sting came from likely hitting a stretch mark.
- 3:02 She reports minimal side effects and says she thought about food less, while admitting she ate ice cream and sweets on Valentine's Day.
- 4:43 She attributes her fatigue to her period, two toddlers and full-time work rather than the medication.
- 5:43 She restarted weight training, planning three strength days and two weighted-vest treadmill walks per week, and she describes her LEMD delivery and kit contents.
Key moments
Where the talk turns, found in the captions. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- tirzepatide
- Point in the journey
- Week 1
- Side effects mentioned
- fatigue
- Who is speaking
- Patient
Questions this video answers
How much weight did she lose in week 1 of compounded tirzepatide?
Heather says she started at 180 lb and weighed 179.2 lb on the morning of the video. She calls herself a slow loser and says she was not expecting rapid results.
What side effects did she have in week 1 of compounded tirzepatide?
She says she had very minimal side effects, and that the dose is only the loading dose. She mentions some fatigue but says she believes it came from her period and a busy life with two toddlers rather than the medication.
Why did her tirzepatide injection sting this week?
Heather says it usually does not sting because she lets the medication lose its chill first. This time she thinks she injected through a stretch mark on her stomach, and she calls it operator error.
What did LEMD send with her compounded tirzepatide order?
She says her order arrived two days after she placed it on a Monday. According to her, it was packaged well and included enough needles and alcohol swabs, plus five anti-nausea pills.
Videos on the same question
The closest videos in the library by what is said in them, not by title.
Tirzepatide Weight Loss by Dose 💉Which One Worked Best? 75+ LBS LostGrace, who posts as Losing It Grace, walks through her experience on each Zepbound (tirzepatide) dose from 2.5 mg to 12.5 mg.
I Moved Up to 5mg on Tirzepatide… I Wasn’t Ready for THIS 😳 (Week 5 Update)In this week 5 update, Heather says she has moved up to 5 mg of compounded tirzepatide, which she gets from LEMD.
My Entire Tirzepatide GLP-1 Weight Loss Experience | 6 Months On, 6 Months Off | Mounjaro, ZepboundMadison Shari describes her experience with compounded tirzepatide, which she says is the main ingredient in Mounjaro and Zepbound.
My Honest Week 3 Update on Compounded Tirzepatide | What ChangedIn this week three update, Heather says she is using compounded tirzepatide through ELMD and restarting GLP-1 treatment for the third time.
4 & 5 week updates + 5 things I gave up while on ZepboundElise, who posts as For Elise Desiree, shares an update covering her fourth and fifth weeks on Zepbound.
From 196 to 157: My 6-Month Compounded Tirzepatide ResultsPamela, who runs the Perfectly Pamela channel, recaps her first 26 weeks on compounded tirzepatide.
About Heather's Health Journey
Patient story, 9.4K subscribers. 8 of their videos are in GLP-1 TV, 290K views between them, mostly on Compounded tirzepatide.
- How I Prep the Day Before My GLP-1 Shot to Avoid Side Effects (Nausea, Fatigue, GI Issues)
- I Moved Up to 5mg on Tirzepatide… I Wasn’t Ready for THIS 😳 (Week 5 Update)
- Compounded Tirzepatide Injection Routine in 2026 | GLP-1 Prep, Timing & Tips
Read next
Our guides closest to what this video covers, with prices checked weekly.
- Zepbound dosage chart: every tirzepatide dose, the escalation rule, what each rung lost in the trial, and what it costs
Zepbound has six doses, 2.5 to 15 mg, taken once a week. The label's rule is four weeks at 2.5 mg, then 2.5 mg steps with at least four weeks on each, to a maintenance dose of 5, 10 or 15 mg. In SURMOUNT-1 those three doses lost 15.0, 19.5 and 20.9 percent of body weight over 72 weeks. Direct from Lilly each rung has a price, $299 at 2.5 mg rising to $699 at 10 mg and above, so the chart below carries the dose, the rule, the trial result and the bill in one place, plus the vial and KwikPen concentrations for anyone measuring in units.
- What is Zepbound? Tirzepatide explained: what it treats, how it works, and what it costs
Zepbound is Eli Lilly's brand of tirzepatide, a once-weekly injection that acts on two hormone receptors, GIP and GLP-1. The FDA label approves it, with diet and exercise, for weight reduction in adults with obesity or overweight plus a weight-related condition, and for moderate to severe obstructive sleep apnea in adults with obesity. In the SURMOUNT-5 trial it produced 20.2% average weight loss at 72 weeks against 13.7% for semaglutide. Lilly sells it self-pay from $299 a month.
- Retatrutide: up to 28.3% weight loss in trials, no FDA approval yet, and no legal way to buy it today
Retatrutide is Eli Lilly's experimental weekly injection that acts on three hormone receptors (GIP, GLP-1 and glucagon). In the phase 3 TRIUMPH-1 trial, people on the 12 mg dose lost 28.3% of their weight at 80 weeks by Lilly's efficacy measure (25.0% counting everyone randomized). It is not FDA-approved, has no price, and cannot legally be sold. Lilly plans to file with FDA in Q1 2027. Tirzepatide is the closest thing you can buy now, compounded from $85 a month on our board.
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