GLP-1 TV · Patient story · views checked Oct 2026
My Entire Tirzepatide GLP-1 Weight Loss Experience | 6 Months On, 6 Months Off | Mounjaro, Zepbound
Patient story
Our summary
Madison Shari describes her experience with compounded tirzepatide, which she says is the main ingredient in Mounjaro and Zepbound. She says she lost 34 lbs, stayed on the lowest dose of 2.5 mg for four therapeutic months, then spent two weaning months before stopping. At the time of filming she had been off the medication for 6 months and says she has maintained her weight.
One person's experience, in their words. Not medical advice.
Where Zepbound costs least today
The three cheapest partner programs for Zepbound, all in per month, checked weekly. Brand Zepbound and compounded versions are different products; each row says which it is.
What else the video covers
She explains that after two pregnancies she had about 35 lbs she could not lose, along with fatigue, a heart condition, signs of insulin resistance and hormonal issues. Her cardiologist did not manage GLP-1 prescriptions, so she turned to online clinics. She says she chose tirzepatide over semaglutide because she expected faster loss and fewer side effects, and chose a compounded version because her insurance would not cover the brand. She gives a price of about 350 a month for compounded versus about 550 with a coupon. She reports nausea that peaked around day three after each weekly shot, some fatigue and lightheadedness, and says a sugar-free electrolyte drink helped. She aimed for 100 grams of protein a day and moved from mostly cardio to strength training.
For stopping, she says she dropped to 1.5 mg (15 units), then took it every other week in the last month before quitting. She says hunger and food noise returned a little, but healthier habits, a high protein diet, intermittent fasting and regular exercise kept things manageable. She says she has fluctuated by a couple of pounds, mostly around her cycle, and cautions that her story may not apply to people with chronic obesity or diabetes.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 1:00 She says she gained and lost the same few pounds for nearly a year after two pregnancies, which led her to look into medical weight loss.
- 7:05 She reports that after the first 2.5 mg shot her hunger and cravings dropped, with nausea and fatigue appearing around week two.
- 8:32 She aimed for 100 grams of protein a day and switched from mostly cardio to strength training.
- 9:15 She says she lost about 7 lbs in week one, then 1 to 3 lbs a week, and stayed at 2.5 mg because she was losing steadily.
- 10:45 She reached her 30 lb goal near the end of month four and chose to wean instead of stopping abruptly.
- 11:46 She dropped to 1.5 mg, then dosed every other week, and says she has held her weight for 6 months after stopping.
Key moments
From the creator's own chapters. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- Zepbound, Mounjaro and tirzepatide
- Point in the journey
- Month 6
- Side effects mentioned
- nausea and fatigue
- Who is speaking
- Patient
Questions this video answers
How much weight did she lose on compounded tirzepatide at 2.5 mg?
She says she lost 34 lbs in total, staying on the 2.5 mg dose for four therapeutic months plus two weaning months. She reports about 7 lbs in the first week, then 1 to 3 lbs a week.
How did she come off tirzepatide without regaining weight?
She says she weaned by dropping to 1.5 mg (15 units), then taking it every other week before stopping fully. She credits high protein eating, intermittent fasting and regular exercise, and says she stayed at her stopping weight for 6 months.
What side effects did she have on tirzepatide?
She reports on and off nausea that peaked about three days after her shot, some fatigue and weakness, and occasional lightheadedness when standing. She says a sugar-free electrolyte drink once a day helped.
How much did compounded tirzepatide cost her?
She says that with a coupon the brand version would have been about 550 a month, and the compounded version brought it down to about 350 a month. She says her insurance would not cover it.
Videos on the same question
The closest videos in the library by what is said in them, not by title.
How to Know When to Titrate Up 7.5 Mounjaro Zepbound TirzepatideAlly of the FitFlavorFun channel explains how she decides it is time to move up a dose of Mounjaro (tirzepatide).
How Much Weight I Lost On Tirzepatide By Week | Mounjaro, Zepbound, Compound Weight LossMadison, who shares videos about her own experience, says she lost more than 30 lbs on compound tirzepatide and has now stopped.
How I Weaned Off My GLP-1 | Tirzepatide Weight Loss And MaintenanceMadison Shari describes how she stopped taking compounded tirzepatide after six months.
I started Tirzepatide! Weight loss medication, Week 1, How much I lost, symptoms & more!Tiffany, who runs The Fasho Life channel, describes her first week on tirzepatide, which she says she has taken for less than two weeks.
I transformed in 6 Months on Mounjaro: The Honest Review (With Before & After Photos)Gordon, who runs the FatOldClimber channel, reviews his first six months on Mounjaro (tirzepatide), starting with his first injection on November 11, 2024.
🛑STARTING MOUNJARO/ZEPBOUND🛑 2.5 mg dose what to expect the first month!Brittany, a creator who says she has lost 83 lbs on Mounjaro (tirzepatide) since November 2022, explains what she thinks new users should expect from the 2.5 mg starter dose.
About Madison Shari
Patient story, 29.9K subscribers. 8 of their videos are in GLP-1 TV, 224K views between them, mostly on Zepbound, Mounjaro, Compounded tirzepatide.
- How Much Weight I Lost On Tirzepatide By Week | Mounjaro, Zepbound, Compound Weight Loss
- Mounjaro, Zepbound, Compound Tirzepatide Weight Loss Tips For Success
- How I Weaned Off My GLP-1 | Tirzepatide Weight Loss And Maintenance
Read next
Our guides closest to what this video covers, with prices checked weekly.
- Mounjaro for weight loss, and why Zepbound exists
Mounjaro is tirzepatide approved for type 2 diabetes. Zepbound is the same molecule from the same maker, approved for weight management, and it goes to the same 15 mg. So unlike Ozempic and Wegovy, there is no dose ceiling pushing you from one to the other: the reason people move is coverage and cash price, not strength. Using Mounjaro for weight is off-label and a prescriber's decision. In the one head-to-head trial, tirzepatide beat semaglutide, 20.2% mean body-weight loss at 72 weeks against 13.7%.
- Mounjaro side effects: the label's numbers by dose, the low blood sugar risk, and how tirzepatide compares at weight-loss doses
On Mounjaro's own label, the common side effects are stomach ones and they rise with the dose: nausea in 12, 15 and 18 percent of people at 5, 10 and 15 mg against 4 percent on placebo, diarrhea 12 to 17 against 9, and any gastrointestinal reaction in 37 to 44 percent against 20. Most of it happens while the dose is being raised and fades. Low blood sugar is rare on Mounjaro alone and is mainly a risk when it is added to insulin or a sulfonylurea. Below: the full table, the rare warnings, and why Zepbound's numbers for the same molecule look higher.
- What is Zepbound? Tirzepatide explained: what it treats, how it works, and what it costs
Zepbound is Eli Lilly's brand of tirzepatide, a once-weekly injection that acts on two hormone receptors, GIP and GLP-1. The FDA label approves it, with diet and exercise, for weight reduction in adults with obesity or overweight plus a weight-related condition, and for moderate to severe obstructive sleep apnea in adults with obesity. In the SURMOUNT-5 trial it produced 20.2% average weight loss at 72 weeks against 13.7% for semaglutide. Lilly sells it self-pay from $299 a month.
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