GLP-1 TV · Patient story · views checked Oct 2026
8 Things I Wish I Knew On Day 1 Of Zepbound
Patient story
Our summary
Jill, a 44-year-old mom of 10 who runs the 2.0 Mommy channel, shares what she wishes she had known at the start of Zepbound. She says she has been on the medication since February 2024, about 15 months at the time of recording, has lost a total of 80 lbs, and is currently on 5 mg. She calls starting Zepbound the best decision she could have made for her health. The video is aimed at people in their first month.
One person's experience, in their words. Not medical advice.
Where Zepbound costs least today
The three cheapest partner programs for Zepbound, all in per month, checked weekly. Brand Zepbound and compounded versions are different products; each row says which it is.
What else the video covers
She begins with routines. Because many people on these medications have little appetite, she suggests setting an eating schedule so you still get enough calories. She also recommends a daily water goal, such as half your body weight in ounces, which she says can help with nausea and constipation. On diet, she says to make each bite count: prioritize protein, and she describes aiming for 1 g per pound of ideal body weight (130 g for her 130 lb ideal weight). She adds fiber, increased slowly alongside water, and moderate healthy fats such as avocado, nuts and olive oil, while skipping greasy fried foods.
For side effects, Jill says to stay ahead of constipation with something like MiraLAX, Colace or magnesium. She says her nausea lasted about the first month, mostly the first 2 or 3 days after each injection, and that small meals, ginger tea and peppermint tea can help. She prefers staying on a dose as long as it is working, since she says higher doses do not necessarily mean faster weight loss and can bring worse side effects. She closes by recommending meal prep or batch cooking protein, and says the first month is about building a foundation rather than doing everything perfectly.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 1:01 Jill suggests setting an eating schedule and a daily water goal, since appetite and thirst may both be low.
- 2:43 She recommends prioritizing protein, using about 1 g per pound of ideal body weight, which was 130 g for her.
- 3:33 She says to raise fiber slowly and drink more water at the same time, and to favor healthy fats over greasy fried foods.
- 6:07 To prevent side effects, she suggests staying ahead of constipation with a supplement and eating small meals to manage nausea.
- 7:00 She says higher doses do not necessarily mean faster weight loss and prefers staying on a dose as long as it works.
- 7:51 She recommends meal prepping or batch cooking protein so food is ready when appetite is low.
Key moments
From the creator's own chapters. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- Zepbound
- Point in the journey
- Day 1
- Side effects mentioned
- nausea, constipation and heartburn or reflux
- Who is speaking
- Patient
Questions this video answers
How much protein should you eat on Zepbound?
Jill says she used 1 g of protein per pound of ideal body weight. Her ideal weight was 130 lbs, so she aimed for 130 g and got close most days. She adds that anyone working with a dietitian should follow their guidance.
How long does nausea last when starting Zepbound?
According to Jill, nausea was mostly limited to the first month. For her it showed up in the 2 or 3 days after each injection. She says small meals, ginger tea and peppermint tea helped.
How much water should you drink on Zepbound?
Jill suggests choosing a daily goal, with half your body weight in ounces as a starting point if a gallon is too much. She says staying hydrated can help with nausea and constipation.
What foods does she avoid on Zepbound?
Jill says to skip greasy fried foods, because the medication slows digestion and heavy food sitting in the stomach feels bad, especially with heartburn or acid reflux. She also says healthy fats are fine but add up quickly in calories.
Videos on the same question
The closest videos in the library by what is said in them, not by title.
8 thing I wish I knew before starting my Zepbound journey so I’m sharing with you.Cheryl, who runs the Simply Sunshine channel, says she has been taking Zepbound for 13 months.
1 YEAR on the LOWEST DOSE of ZEPBOUND?? The return of food noise / weightloss before and after /glp1Kristen, who posts as Feed Crissy, marks one year on Zepbound with an update on her weight, her eating and how she feels about the medication.
DAY 5 ZEPBOUND: *Why* Am I Still Hungry On Zepbound Weight Loss?! // STILL HUNGRY ZEPBOUNDIn this episode, Elizabeth says she has lost over 90 pounds in 17 months on GLP-1 medication.
Stopping Zepbound the Wrong Way (What I Learned)The creator says she restarted Zepbound after being off it for 7 months.
5 Tips to Lose 50 lbs with ZepboundIn this video from the DOWNSIZED channel, Lorraine Durham says she lost 50 pounds on compounded tirzepatide, which she obtained through Mochi Health Online because her insurance does not cover weight loss medications.
What To Expect On Zepbound (25 tips and mistakes to avoid)In this 31 minute video, the creator shares 25 tips and mistakes to avoid for people starting Zepbound, based on her own two years on the medication.
About 2.0 Mommy
Patient story, 17.2K subscribers. 8 of their videos are in GLP-1 TV, 255K views between them, mostly on Zepbound, Mounjaro.
- 7 Months Off Zepbound: The Truth
- What To Expect On Zepbound (25 tips and mistakes to avoid)
- Why You’re Tired On Zepbound: Plus 5 Ways To Fix It!
Read next
Our guides closest to what this video covers, with prices checked weekly.
- Zepbound dosage chart: every tirzepatide dose, the escalation rule, what each rung lost in the trial, and what it costs
Zepbound has six doses, 2.5 to 15 mg, taken once a week. The label's rule is four weeks at 2.5 mg, then 2.5 mg steps with at least four weeks on each, to a maintenance dose of 5, 10 or 15 mg. In SURMOUNT-1 those three doses lost 15.0, 19.5 and 20.9 percent of body weight over 72 weeks. Direct from Lilly each rung has a price, $299 at 2.5 mg rising to $699 at 10 mg and above, so the chart below carries the dose, the rule, the trial result and the bill in one place, plus the vial and KwikPen concentrations for anyone measuring in units.
- How to get Zepbound: who qualifies, who prescribes it, and the four ways to pay
Zepbound is a prescription drug approved for adults with obesity, or overweight with at least one weight-related condition, which the trials defined as a BMI of 30, or 27 with a comorbidity. Any licensed prescriber can write it, including online. Then it is a payment question with four answers: a commercial plan that covers it brings it to $25 with Lilly's card; Lilly sells it direct for $299 to $699 a month by dose; a plan that refuses can be appealed; and compounded tirzepatide, the same molecule without FDA approval, starts at $85 on our board.
- Mounjaro for weight loss, and why Zepbound exists
Mounjaro is tirzepatide approved for type 2 diabetes. Zepbound is the same molecule from the same maker, approved for weight management, and it goes to the same 15 mg. So unlike Ozempic and Wegovy, there is no dose ceiling pushing you from one to the other: the reason people move is coverage and cash price, not strength. Using Mounjaro for weight is off-label and a prescriber's decision. In the one head-to-head trial, tirzepatide beat semaglutide, 20.2% mean body-weight loss at 72 weeks against 13.7%.
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