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GLP-1 TV · Patient story · views checked Oct 2026

Trying Wegovy | Weight Loss Journey | WEEK 1 | Meal Prep 🥘

Patient storyMichelle Lee10,299 views13:48Feb 2023

Our summary

Michelle Lee records the start of her first week on Wegovy, beginning on Sunday, February 12th. She says she is using the medication to help curb her appetite and cravings, and she plans to document the process in case it helps others. She explains that the pen is injected once a week, that each box holds four pre-loaded pens, and that treatment starts at a low dose, which for her is 0.25 mg. She films herself giving the first injection in her upper right thigh and describes the steps her doctor's office taught her: twist off the cap, press the pen to the skin, wait for the clear section to turn yellow, and hold it for about 10 seconds between two clicks. She says it felt like a tiny prick and did not hurt. She also says she will rotate injection sites and reminds viewers to check with their own doctor before changing anything.

One person's experience, in their words. Not medical advice.

What else the video covers

She lists the side effects she has heard about from her doctor and from other videos: nausea, vomiting, headaches and tiredness. She says she plans to meal prep, walk every day, and follow a low carb, high protein diet with fewer calories.

In a day two update, she reports being very tired on day one, to the point of dozing off in church despite coffee and an energy drink. She also describes strong thirst, almost no appetite on both days, and a pulsing headache behind her left eye during the Super Bowl party that eased after Tylenol and food. She notes it may have been a hunger headache and says she is unsure which symptoms come from the medication. The video ends with a brief unrelated meal prep clip.

Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.

Takeaways

The main points, in the order they come up. Tap a time to play from there.

  1. 0:31 Michelle says she is starting Wegovy, a once weekly injection, at 0.25 mg to help with appetite and cravings.
  2. 2:00 Her doctor told her to start in the thigh, and she plans to alternate legs each week to avoid bruising or soreness.
  3. 4:05 She walks through the pen steps: press it to the skin, watch for yellow, and wait 10 seconds between two clicks.
  4. 6:26 She says the injection did not hurt, then lists nausea, vomiting, headaches and tiredness as side effects she expects to watch for.
  5. 7:10 She plans to meal prep, walk daily, and eat low carb and high protein with fewer calories.
  6. 8:43 On day two she reports fatigue, intense thirst, no appetite, and a strong headache the evening of day one.

Key moments

From the creator's own chapters. Tap one to play from there.

  1. 0:00 Starting a new journey
  2. 1:03 Administering the injection
  3. 8:14 First week weigh in
  4. 8:23 Day two side effects

What the video says

As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.

Medication
Wegovy
Point in the journey
Week 1
Side effects mentioned
nausea, fatigue and headache
Who is speaking
Patient

Questions this video answers

How do you use the Wegovy pen for the first injection?

Michelle says the pen comes pre-loaded, and her doctor's office told her to twist off the cap and press the pen against the skin. She says the window turns yellow as the medication dispenses, and she waits 10 seconds between two clicks before removing it.

What dose of Wegovy do you start with?

Michelle says she started at 0.25 mg, taken once a week. She says each box contains four pre-loaded pens at that starting dose.

What side effects did she have in the first two days on Wegovy?

She reports tiredness, strong thirst, very little appetite and a headache behind her left eye on day one, with a slight headache on day two. She says she is not sure whether all of it was from the medication.

Where does she inject Wegovy and does it hurt?

She says her doctor told her to start in the thigh and she used her upper right thigh, planning to switch legs weekly. She describes it as a tiny prick that did not hurt.

Videos on the same question

The closest videos in the library by what is said in them, not by title.

Read next

Our guides closest to what this video covers, with prices checked weekly.

  • Wegovy 7.2 mg (Wegovy HD): what the higher dose adds, and what it costs

    Wegovy HD is semaglutide at 7.2 mg, three times the standard 2.4 mg dose, in its own pen. In the STEP UP trial it took 18.7% off body weight at 72 weeks against 15.6% for 2.4 mg and 3.9% for placebo, in 1,407 adults with obesity. That puts it within 1.5 points of tirzepatide's head-to-head result and makes it the strongest semaglutide there is. Novo sells it direct for $399 a month, $50 above the standard pen, and it sits above the normal ladder rather than replacing it.

  • Wegovy side effects, and why the top of the ladder is different

    Wegovy's side effects are semaglutide's side effects: nausea, vomiting, diarrhoea and constipation, worst in the first weeks and after each dose increase. What makes Wegovy different from Ozempic is not the molecule but the destination. Wegovy is dosed for weight management, climbing to 2.4 mg with a 7.2 mg high-dose strength above it, and dose is the main driver of how pronounced the gastrointestinal effects get. It also carries a boxed warning for thyroid C-cell tumour risk. One useful fact while you decide whether to push through: Novo's self-pay price is flat across every pen dose, so a slower climb costs a brand patient nothing.

  • Wegovy pill vs injection: the same semaglutide, two schedules, two price lists

    The Wegovy pill and the Wegovy pen are the same drug, semaglutide. The pill is one tablet a day on an empty stomach with a little water; the pen is one injection a week at any time. Novo's cash price is $149 to $299 a month for the pill by strength and $349 for the pen. In separate placebo trials the top tablet dose and the pen produced similar average weight loss.

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Side effectsDose changeFood, protein and eatingFood noise and cravingsInjection techniqueAlcoholNauseaFatigueHeadache

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