GLP-1 TV · Patient story · views checked Oct 2026
From 196 to 157: My 6-Month Compounded Tirzepatide Results
Our summary
Pamela, who runs the Perfectly Pamela channel, recaps her first 26 weeks on compounded tirzepatide. She says she is 54, postmenopausal and 5'2", and that she started on November 22, 2024 at 196.9 lb on a 2.5 mg dose. She reports reaching 157.8 lb at the six-month mark, a total loss of 39.1 lb. The video goes week by week through her weigh-ins, struggles and side effects.
One person's experience, in their words. Not medical advice.
Where tirzepatide costs least today
The three cheapest partner programs for tirzepatide, all in per month, checked weekly.
What else the video covers
She describes a fast start, with 4 lb lost in week one and 8.4 lb down after two weeks, followed by a slower pace. Side effects she mentions include dry mouth, constipation, occasional headaches that she links to work stress, brief nausea after one injection, and tiredness on the weekends after her Friday dose. She says she tried 5 mg at week six, could not eat enough and was constipated, so with her provider she dropped back to 3.75 mg and then to 2.5 mg before stepping up more gradually. She also says she switched from an Empower compound containing niacinamide to a Hallandale one with no additives. By week 24 she moved to 5.95 mg. She lists the constipation aids she used, including Dulcolax, Colace and Mag O7.
Later sections cover hair shedding and brittle nails that she ties to low protein, her effort to raise calories and protein, and the point where around 1,500 calories a day seemed best for her. She says her foot pain eased and her food noise dropped. She closes by saying scale weight is not the only measure and that she tracks measurements every 4 weeks. Everything here is her personal experience, not medical advice.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 1:31 She says she started compounded tirzepatide at 2.5 mg on November 22, 2024 at 196.9 lb and lost 8.4 lb in the first two weeks.
- 8:59 She reports that moving to 5 mg in week six was too much, causing constipation and trouble eating, so she dropped back to 3.75 mg and then 2.5 mg with her provider.
- 16:02 She describes switching from an Empower compound with niacinamide to a Hallandale compound with no additives in week 13.
- 19:57 She says hair shedding and brittle nails around week 17 led her to focus on getting more protein.
- 29:05 She reports moving to 5.95 mg at week 24 and reaching 159.2 lb at week 25, her first time in the 150s in about 20 years.
- 34:45 She reports ending week 26 at 157.8 lb, 39.1 lb down, and says her foot pain eased and she urges tracking more than the scale.
Key moments
From the creator's own chapters. Tap one to play from there.
- 0:00 Intro: My 6-Month Tirzepatide Journey
- 0:58 Starting Point: Stats & First Dose
- 2:29 First Injection: Nerves & Initial Reaction
- 4:25 Week 1: Thanksgiving & 4lb Loss!
- 5:03 Week 2: Feeling a Pro & Coffee Aversion
- 6:17 Week 3: First Side Effects & Travel
- 7:27 Week 4: Managing Expectations & Headaches
- 9:05 Week 5: A Small Gain & Food Noise Returns
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- tirzepatide
- Doses mentioned
- 2.5 mg and 5 mg
- Point in the journey
- Month 6
- Weight loss mentioned
- 4 lb
- Side effects mentioned
- nausea, constipation, fatigue, headache and low appetite
- Who is speaking
- Patient
Questions this video answers
How much weight did she lose in 6 months on compounded tirzepatide?
Pamela says she went from 196.9 lb to 157.8 lb over 26 weeks, a total loss of 39.1 lb. She says the loss was fastest in the first two weeks and slower afterward.
What side effects did she have on compounded tirzepatide?
She mentions dry mouth, constipation, headaches she links to stress, brief nausea after one injection, fatigue on weekends and hair and nail changes. She says she managed constipation with Dulcolax, Colace and Mag O7.
Did she follow the usual dose increase schedule on tirzepatide?
No. She says she stayed on 2.5 mg past four weeks because it was still working, then found 5 mg too much at week six and returned to lower doses. She later stepped up through 3.75 mg, 4.15 mg and 5 mg before moving to 5.95 mg at week 24, with her provider's agreement.
Videos on the same question
The closest videos in the library by what is said in them, not by title.
First month on compounded tirzepatide #zepBound #mounjaro for Fast Weight Loss.In this video, a woman who introduces herself as Ebony (the channel is named Bianca) reports on her first month taking compounded tirzepatide.
Week 1 on Compounded Tirzepatide: Side Effects, Appetite & Real ResultsIn this week 1 update, Heather says she started compounded tirzepatide at 180 lb and weighed 179.2 lb on the morning she recorded the video.
How Much Weight I Lost On Tirzepatide By Week | Mounjaro, Zepbound, Compound Weight LossMadison, who shares videos about her own experience, says she lost more than 30 lbs on compound tirzepatide and has now stopped.
I Moved Up to 5mg on Tirzepatide… I Wasn’t Ready for THIS 😳 (Week 5 Update)In this week 5 update, Heather says she has moved up to 5 mg of compounded tirzepatide, which she gets from LEMD.
My 1-Month Update on Compounded Tirzepatide | Brutally Honest & REAL ADVICENelly Jane gives an update on her weight loss with compounded tirzepatide.
Read next
Our guides closest to what this video covers, with prices checked weekly.
- Retatrutide: up to 28.3% weight loss in trials, no FDA approval yet, and no legal way to buy it today
Retatrutide is Eli Lilly's experimental weekly injection that acts on three hormone receptors (GIP, GLP-1 and glucagon). In the phase 3 TRIUMPH-1 trial, people on the 12 mg dose lost 28.3% of their weight at 80 weeks by Lilly's efficacy measure (25.0% counting everyone randomized). It is not FDA-approved, has no price, and cannot legally be sold. Lilly plans to file with FDA in Q1 2027. Tirzepatide is the closest thing you can buy now, compounded from $85 a month on our board.
- Tirzepatide dosage chart: the 2.5 to 15 mg ladder, week by week, and what each step costs
Tirzepatide starts at 2.5 mg weekly for 4 weeks, then climbs in 2.5 mg steps of at least 4 weeks to 15 mg max. The chart, the units and the cost per step.
- Tirzepatide vs semaglutide: the head-to-head result, and what the better one costs
They were finally tested against each other. In SURMOUNT-5, 751 adults with obesity took the maximum tolerated dose of one or the other for 72 weeks: tirzepatide lost 20.2% of body weight, semaglutide 13.7%. That gap is real and it is the whole argument for tirzepatide. The other half of the decision is the bill: compounded tirzepatide runs from $85 a month on our board against $69 for semaglutide, and the branded gap is wider still.
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