GLP-1 TV · Patient story · views checked Oct 2026
Direct Meds GLP1 sublingual (oral) Tirzepatide
Our summary
Venessa Estrada, who introduces herself as Vanessa, films her first day on sublingual tirzepatide drops from Direct Meds. She says she saw a TikTok ad, completed the online intake on September 5th, was approved, and received the package on the 10th. She chose the drops because she is terrified of syringes and the company did not offer pre-filled pens. She says she has struggled with weight loss and diets for years, and that an earlier attempt with HCG drops made her feel nervous.
One person's experience, in their words. Not medical advice.
Direct Meds today
Named in this video. The price is today's, read off the program's own site, all in per month; what a video says it paid can be months old.
Where tirzepatide costs least today
The three cheapest partner programs for tirzepatide, all in per month, checked weekly.
What else the video covers
She unboxes the package, which includes a vial of liquid and two droppers. She reads the instructions aloud: shake well, do not refrigerate, brush teeth and gums right before use, hold the liquid under the tongue for at least 5 minutes (longer if possible), then swallow, and wait at least 60 minutes before food, drink or other medications. She says she believes she got the three-month deal, and mentions $199 plus a $200 coupon. She reads the listed side effects, including nausea, diarrhea, vomiting, constipation, stomach pain, headache, tiredness, dizziness, bloating and low blood sugar. She waited for a day off because she works graveyard shifts.
She takes a 0.3 dose and holds it for 10 minutes 17 seconds. She says it tasted minty, and the label lists peppermint oil and spearmint oil. She says she felt nothing unusual right after. She plans to take 0.3 mg for 4 weeks, do a weigh-in and before photos, and report back after the month. She says she made the video because she could not find information on this product online, and that she is inexperienced with it.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 0:04 According to the instructions she reads, the drops should be shaken, not refrigerated, and held under the tongue for at least 5 minutes before swallowing.
- 0:31 She says she decided to start after seeing a Direct Meds ad, and picked the sublingual option because she is afraid of syringes.
- 2:00 She says she completed intake on September 5th, was approved, and received her package on the 10th.
- 7:07 She reads out the listed side effects and says she waited for her day off before starting.
- 8:48 She holds the dose under her tongue for 10 minutes 17 seconds and describes the taste as minty.
- 10:19 She says the plan is 0.3 mg for 4 weeks, with a weigh-in and before photos now and a follow-up after the month.
Key moments
Where the talk turns, found in the captions. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- tirzepatide
- Side effects mentioned
- nausea and fatigue
- Who is speaking
- Patient
Questions this video answers
How do you take sublingual tirzepatide drops?
According to the instructions she reads, you shake the vial, place the measured amount under the tongue, and hold it there for at least 5 minutes or longer if possible before swallowing. She says the instructions also call for brushing teeth and gums right before and waiting at least 60 minutes before food, drink or other medications.
Do sublingual tirzepatide drops need to be refrigerated?
She says the paperwork tells you not to refrigerate them. She repeats this when summarizing the process near the end of the video.
What does sublingual tirzepatide taste like?
She describes it as minty with a little spice and says it was not a bad taste. She says the label lists peppermint oil and spearmint oil.
How long did it take to get sublingual tirzepatide from Direct Meds?
She says she did the intake on September 5th, was approved, and received her package on the 10th. She describes the process as fast.
Videos on the same question
The closest videos in the library by what is said in them, not by title.
Week 1 on Compounded Tirzepatide: Side Effects, Appetite & Real ResultsIn this week 1 update, Heather says she started compounded tirzepatide at 180 lb and weighed 179.2 lb on the morning she recorded the video.
Tirzepatide Side Effects by Dose: What to Expect From 2.5mg to 10mgIn this video, a creator from the Losing It Grace channel goes through the side effects she says she had on each Zepbound (tirzepatide) dose, from 2.5mg up to 10mg.
What the FDA update means for US | Foundayo is here! Weekly GLP1 update Brittany Rose, who says she lost 115 lb on a GLP-1, covers two news items from the previous week.
GLP-1 Update - 7.5MG IS MY MAGIC DOSE!!! WEIGHTLOSS JOURNEY; ZEPBOUND/TIRZEPATIDEKeisha, who runs the channel Keeping Up with Keisha, gives an update on moving up to 7.5 mg of tirzepatide (Zepbound).
Read next
Our guides closest to what this video covers, with prices checked weekly.
- Zepbound dosage chart: every tirzepatide dose, the escalation rule, what each rung lost in the trial, and what it costs
Zepbound has six doses, 2.5 to 15 mg, taken once a week. The label's rule is four weeks at 2.5 mg, then 2.5 mg steps with at least four weeks on each, to a maintenance dose of 5, 10 or 15 mg. In SURMOUNT-1 those three doses lost 15.0, 19.5 and 20.9 percent of body weight over 72 weeks. Direct from Lilly each rung has a price, $299 at 2.5 mg rising to $699 at 10 mg and above, so the chart below carries the dose, the rule, the trial result and the bill in one place, plus the vial and KwikPen concentrations for anyone measuring in units.
- Microdosing GLP-1s: what it saves you, and what it doesn't
Microdosing a GLP-1 does not save money at a compounded seller: none of the compounded programs we track charges less for a smaller dose. Microdosing is not a medical term, and no dose below the label's starting dose has been studied for this. The one microdosing product on our board costs more a month than full-dose compounded tirzepatide at the cheapest seller we track. Where dose really moves the price is the brands; the provider table, per-mg costs and live numbers are below.
- Compounded tirzepatide: what it is, what FDA says now the shortage is over, and what it costs against Zepbound
Compounded tirzepatide is Zepbound's molecule made by a licensed pharmacy rather than Lilly, sold through telehealth programs from $85 a month on our board against Lilly's $299 to $699 ($449 on the KwikPen from 7.5 mg with on-time refills). It is not FDA-approved, and the legal ground under it has shifted: FDA says tirzepatide no longer appears on its shortage list, which was the condition that let pharmacies compound copies of an approved drug at scale. What remains is compounding for individual patients, FDA's list of specific concerns about how these products are dosed, shipped and labelled, and a price gap large enough that most cash buyers take the trade anyway. This page sets all of that out.
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