GLP-1 TV · Patient story · views checked Oct 2026
Zepbound - 2 week update on 7.5mg
Our summary
Elise, who posts as For Elise Desiree, says she has moved up to 7.5mg of Zepbound after about six months on the medication. She explains that her first three months of weight loss went well, with 2.5mg in month one and then 5mg for four months. In month four, she says, loss slowed sharply. It took her five weeks to lose the last four pounds toward a 30 pound first goal, and she went two or three weeks with no loss at all despite steps, water, sleep, fiber and protein. She says her doctor agreed that moving up was acceptable even when loss is slower, and she says she felt some shame about the decision after commenters warned against going up too fast.
One person's experience, in their words. Not medical advice.
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The three cheapest partner programs for Zepbound, all in per month, checked weekly. Brand Zepbound and compounded versions are different products; each row says which it is.
What else the video covers
She reports side effects since starting 7.5mg two weeks ago. Her appetite suppression has returned, which she says had faded on 5mg. She also says she feels very sleepy and tired, to the point of shortening her workouts from 45 minutes to 30, and that she feels cold much more than before. She notes her labs, including iron and thyroid, were normal a week before the increase, and she is unsure whether the tiredness and the cold are connected.
She also describes a five day trip to New Orleans for her and her husband's birthdays. She says she ate and drank freely with no eating window and was up 5.5 pounds when she weighed in afterward. It took 13 days to get back to 156 pounds. She says she has no regrets, but that she plans to keep a closing time for eating on future trips. She ends by saying she started at 186 pounds and is back at her 30 pound loss.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 0:00 Elise says she moved up to 7.5mg of Zepbound after six months, having used 2.5mg for one month and 5mg for four months.
- 0:32 She says her fourth month slowed down, with five weeks to lose the last four pounds of a 30 pound goal.
- 1:07 She says her doctor told her it is fine to go up a dose when loss slows, and she felt some shame about it.
- 3:37 She reports that appetite suppression came back on 7.5mg, along with sleepiness, tiredness and feeling cold.
- 6:14 She says a New Orleans trip caused a 5.5 pound gain that took 13 days to lose.
- 9:46 She recaps that she started at 186 pounds and is now at 156 pounds, a 30 pound loss, after two weeks on 7.5mg.
Key moments
From the creator's own chapters. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- Zepbound
- Doses mentioned
- 5 mg and 7.5 mg
- Point in the journey
- Week 2
- Side effects mentioned
- fatigue and low appetite
- Who is speaking
- Patient
Questions this video answers
Why did she move up to 7.5mg of Zepbound?
Elise says her weight loss slowed in her fourth month, including a plateau of two or three weeks, and 5mg felt like it had stopped working for her. She says her doctor agreed it was fine to increase the dose when loss slows.
What side effects did she have on Zepbound 7.5mg?
She says she became very sleepy and tired and felt cold much more than usual. She also says her appetite suppression returned. She reports that her labs, including iron and thyroid, were normal before the increase.
How much weight did she lose on Zepbound in six months?
Elise says she started at 186 pounds and is now at 156 pounds, a loss of 30 pounds after about six months on Zepbound. She says she had briefly regained 5.5 pounds on a trip and took 13 days to lose it.
Videos on the same question
The closest videos in the library by what is said in them, not by title.
Zepbound Week 61: The Dose Was the ProblemIn this week 61 update, the creator says she gained 13.8 pounds in 11 days after her Zepbound dose was lowered from 5 milligrams to 2.5 milligrams.
My Experience Titrating From 5 mg to 7.5 mg on ZepboundIn this video, the creator of the All About A-Marie channel describes moving from the 5 mg dose of Zepbound to 7.5 mg.
Stopping Zepbound the Wrong Way (What I Learned)The creator says she restarted Zepbound after being off it for 7 months.
I tried Zepbound 2.5mg for 2 weeks | Appetite, Weight, & Side EffectsIn this first weigh-in video, Millennial Meg describes the end of her second week on Zepbound 2.5mg.
Read next
Our guides closest to what this video covers, with prices checked weekly.
- Zepbound dosage chart: every tirzepatide dose, the escalation rule, what each rung lost in the trial, and what it costs
Zepbound has six doses, 2.5 to 15 mg, taken once a week. The label's rule is four weeks at 2.5 mg, then 2.5 mg steps with at least four weeks on each, to a maintenance dose of 5, 10 or 15 mg. In SURMOUNT-1 those three doses lost 15.0, 19.5 and 20.9 percent of body weight over 72 weeks. Direct from Lilly each rung has a price, $299 at 2.5 mg rising to $699 at 10 mg and above, so the chart below carries the dose, the rule, the trial result and the bill in one place, plus the vial and KwikPen concentrations for anyone measuring in units.
- How long do Ozempic, Wegovy and Zepbound take to work? The label calendar and the trial timepoints
GLP-1s act from the first dose, but the labels start low on purpose and step up every 4 weeks, so most people do not reach a full dose for 3 to 5 months. Each dose reaches steady levels in the blood after about 4 to 5 weeks. In the trials, people averaged 10.6% weight loss after 20 weeks of Wegovy's escalation and 20.9% after 36 weeks of Zepbound, with the full trial results at 68 to 72 weeks. For type 2 diabetes, Ozempic's A1C results were measured at week 30.
- Mounjaro for weight loss, and why Zepbound exists
Mounjaro is tirzepatide approved for type 2 diabetes. Zepbound is the same molecule from the same maker, approved for weight management, and it goes to the same 15 mg. So unlike Ozempic and Wegovy, there is no dose ceiling pushing you from one to the other: the reason people move is coverage and cash price, not strength. Using Mounjaro for weight is off-label and a prescriber's decision. In the one head-to-head trial, tirzepatide beat semaglutide, 20.2% mean body-weight loss at 72 weeks against 13.7%.
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