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GLP-1 TV · Patient story · views checked Oct 2026

Mounjaro Week 2: (tirzepatide 2.5mg) Results?! Side effects, weight loss?

Patient storyCaz Life27,057 views8:23Dec 2024

Our summary

In this short update, the creator, who goes by Caz Life, describes her second week on Mounjaro (tirzepatide 2.5mg). She says week two felt easier than week one. Her side effects were mild: the appetite suppression stayed gentle, and she reports fatigue, headaches that increased this week, some dehydration and slight constipation. She says she has been drinking more water and links the constipation to dehydration.

One person's experience, in their words. Not medical advice.

What else the video covers

She says the biggest change is that she no longer feels the pull to snack in the evening, even after eating around 1,200 calories in a day. She also mentions getting a little hungry near the end of the week before her next injection, and feeling hungrier the day after a run of sweaty classes or weight training. She teaches exercise classes six days a week, some of them gentle Pilates or yoga.

She gives her numbers. She says she lost three pounds in week one, then started week two at 12 stone 0 pounds 6 ounces by her reading and weighed in at 12 stone 12 pounds, a loss of 2 pounds 2 ounces. She reports a BMI of 28.3 (down from 29), body fat of 35.9% (down from 36.5%), and subcutaneous fat of 32.1 (from 32.6 on day one), with visceral fat unchanged. Her total is 5 pounds in just over two weeks. She says she has about a stone and a half to two stone left to lose and that she found nothing negative in week two.

Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.

Takeaways

The main points, in the order they come up. Tap a time to play from there.

  1. 0:10 She says week two was an easier transition than week one, with mild appetite suppression and no major side effects.
  2. 0:41 She reports more headaches, dehydration and slight constipation this week, and says she increased her water intake.
  3. 1:52 She says she no longer wants evening snacks, even after about 1,200 calories in a day.
  4. 3:14 She reports losing 2 pounds 2 ounces in week two, after losing three pounds in week one.
  5. 3:45 She shares BMI of 28.3, body fat of 35.9% and subcutaneous fat of 32.1, with visceral fat unchanged.
  6. 5:24 She reports 5 pounds lost in just over two weeks, and says she gets a little hungry before her injection and hungrier after intense workout days.

Key moments

From the creator's own chapters. Tap one to play from there.

  1. 0:00 Week 2 side effects
  2. 1:23 Appetite suppression
  3. 2:45 Weight loss statistics
  4. 5:28 Reflections and next steps

What the video says

As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.

Medication
Mounjaro and tirzepatide
Doses mentioned
2.5 mg
Point in the journey
Week 2
Side effects mentioned
fatigue, headache and dehydration
Who is speaking
Patient

Questions this video answers

What side effects did she have in week 2 of Mounjaro 2.5mg?

She says she had fatigue, more frequent headaches, some dehydration and slight constipation, which she links to dehydration. She says she drank more water and otherwise felt fine.

How much weight did she lose in the first two weeks of Mounjaro?

She reports losing three pounds in week one and 2 pounds 2 ounces in week two, for about 5 pounds in just over two weeks. She says her weight went from 13 stone 3 to 12 stone 12.

Did Mounjaro reduce her appetite and snacking?

She says she has enjoyed not feeling hungry and no longer wants evening snacks, even after eating about 1,200 calories. She also says she gets a little hungry at the end of the week before her injection.

What body measurements changed for her after two weeks on Mounjaro?

She reports BMI going from 29 to 28.3 and body fat from 36.5% to 35.9%. She says subcutaneous fat fell from 32.6 to 32.1 while visceral fat did not change.

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  • Mounjaro side effects: the label's numbers by dose, the low blood sugar risk, and how tirzepatide compares at weight-loss doses

    On Mounjaro's own label, the common side effects are stomach ones and they rise with the dose: nausea in 12, 15 and 18 percent of people at 5, 10 and 15 mg against 4 percent on placebo, diarrhea 12 to 17 against 9, and any gastrointestinal reaction in 37 to 44 percent against 20. Most of it happens while the dose is being raised and fades. Low blood sugar is rare on Mounjaro alone and is mainly a risk when it is added to insulin or a sulfonylurea. Below: the full table, the rare warnings, and why Zepbound's numbers for the same molecule look higher.

  • Mounjaro for weight loss, and why Zepbound exists

    Mounjaro is tirzepatide approved for type 2 diabetes. Zepbound is the same molecule from the same maker, approved for weight management, and it goes to the same 15 mg. So unlike Ozempic and Wegovy, there is no dose ceiling pushing you from one to the other: the reason people move is coverage and cash price, not strength. Using Mounjaro for weight is off-label and a prescriber's decision. In the one head-to-head trial, tirzepatide beat semaglutide, 20.2% mean body-weight loss at 72 weeks against 13.7%.

  • Mounjaro vs Ozempic, and the trial everyone quotes about it

    Mounjaro is tirzepatide and Ozempic is semaglutide: different molecules, not two brands of the same drug. Both are approved for type 2 diabetes, and the weight-loss versions are Zepbound and Wegovy. In the one head-to-head trial, SURMOUNT-5, tirzepatide produced 20.2% mean body-weight loss at 72 weeks against semaglutide's 13.7%. The detail almost every page omits: that trial dosed semaglutide to 2.4 mg in people without diabetes, which is the Wegovy range. Ozempic tops out at 2 mg. The famous result did not test Ozempic's dose range.

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