GLP-1 TV · Patient story · views checked Oct 2026
GLP-1 / Zepbound / Tirzepatide Journey | 6 Month update, the good and the bad!
Our summary
Luis Zayas, who says he is 32, marks six months on a GLP-1 medication that he started on November 3, 2025. He says his highest weight was 285 lb, his starting weight was 247 lb, and he weighed 206 lb on the day of recording. That is 41 lb lost, which he puts at an average of 1.6 lb per week against a goal of 1.5 to 2 lb. His goal weight is 170 lb, and he estimates he could reach it around October.
One person's experience, in their words. Not medical advice.
Where Zepbound costs least today
The three cheapest partner programs for Zepbound, all in per month, checked weekly. Brand Zepbound and compounded versions are different products; each row says which it is.
What else the video covers
He describes starting with a free sample box of Mounjaro 2.5 mg from his doctor, who later prescribed Zepbound because he has obstructive sleep apnea rather than diabetes. He says that within about two hours of the first injection his constant urge to negotiate over food went quiet, and that it has stayed quiet since. He reports only mild side effects, such as a knot-like feeling in his stomach after eating and slight nausea. He moved to 5 mg after five weeks on 2.5 mg, calls that a regret, and says he is still on 5 mg with the same rate of loss.
He says he pays $450 a month, picked up at Walmart, and offsets it with $300 a month in insurance money he budgeted and about $200 a month he no longer spends on fast food. He also covers his exercise routine, an urge to rush weight loss that he resisted, the return of normal hunger signals around months two to three, and a 90/10 way of eating that includes about two less nutritious meals a week. These are his personal experiences, not medical advice.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 0:00 Luis says he went from 247 lb to 206 lb in six months, a loss of 41 lb at about 1.6 lb per week.
- 5:05 He says that within about two hours of his first injection he felt his food noise switch off, and that it has stayed gone for six months.
- 9:00 He says he moved from 2.5 mg to 5 mg after five weeks, regrets the speed, and has stayed on 5 mg since.
- 16:56 He says Zepbound was prescribed because of his sleep apnea, and he pays $450 a month with a Walmart pickup.
- 22:38 He describes a brief urge to crash diet near 199 lb that passed, and says he is otherwise happy with how things have gone.
- 33:26 He says he eats a 90/10 plan, with about two less healthy meals a week in small portions.
Key moments
From the creator's own chapters. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- Ozempic, Zepbound, Mounjaro and tirzepatide
- Doses mentioned
- 2.5 mg and 5 mg
- Point in the journey
- Month 6
- Side effects mentioned
- nausea and vomiting
- Prices mentioned
- $300 a month, $200 a month and $550 a month
- Who is speaking
- Patient
Questions this video answers
How much weight can you lose on Zepbound in 6 months?
Luis says he went from 247 lb to 206 lb in six months, a loss of 41 lb. He puts that at an average of 1.6 lb per week, and says the weekly numbers went up and down.
What side effects did he have on Zepbound 5 mg?
He says he felt a knot in his stomach after eating that slowly faded, and had slight nausea without vomiting. He says these were milder than the effects of his binge eating before treatment, and that he does not recall strong diarrhea or constipation.
How much does Zepbound cost per month out of pocket?
Luis says he pays $450 a month and picks it up at Walmart. He says he offsets this with $300 a month he had budgeted for higher insurance and about $200 a month saved on fast food.
What is food noise on a GLP-1 medication?
Luis describes food noise as constantly negotiating with yourself about eating things you know are bad for you, like two voices arguing. He says the medication removed it for him, and that this mattered more to him than feeling less hungry.
Videos on the same question
The closest videos in the library by what is said in them, not by title.
Got Questions About GLP-1s, Zepbound , Wegovy, Foundayo? DOWNSIZED LIVE!In this weekly live Q&A, the hosts of DOWNSIZED say they are not doctors.
My 1-Year, 90 lb Weight Loss Transformation | Real Life + GLP-1 ExperienceLauren, a mom of six who lives in Alaska and runs the This Alaska Life channel, answers viewer questions about her weight loss over the past year.
Zepbound (tirzepatide) My 100+ pounds weight loss journey! #glp1 #zepboundMs. Toy, who runs the channel Ms. Toy The Review, introduces her weight loss story with Zepbound (tirzepatide).
6 Months on a GLP-1: DEXA Scan & Metabolism Results RevealedLenore, who describes herself as a nutritionist and nutrition coach, reports on six months of using a GLP-1, specifically Zepbound.
I Made 7 GLP-1 Mistakes (So You Don't Have To)Bobbi B., a creator who says she is a therapist but not a medical doctor, describes seven mistakes she made over about 70 weeks on a GLP-1.
Coverage for GLP-1 denied after weight lossThis NBC News report follows William Meehan, a Sacramento Sheriff's Deputy who says Zepbound improved his sleep and energy and ended his sleep apnea.
Read next
Our guides closest to what this video covers, with prices checked weekly.
- What is Zepbound? Tirzepatide explained: what it treats, how it works, and what it costs
Zepbound is Eli Lilly's brand of tirzepatide, a once-weekly injection that acts on two hormone receptors, GIP and GLP-1. The FDA label approves it, with diet and exercise, for weight reduction in adults with obesity or overweight plus a weight-related condition, and for moderate to severe obstructive sleep apnea in adults with obesity. In the SURMOUNT-5 trial it produced 20.2% average weight loss at 72 weeks against 13.7% for semaglutide. Lilly sells it self-pay from $299 a month.
- Zepbound dosage chart: every tirzepatide dose, the escalation rule, what each rung lost in the trial, and what it costs
Zepbound has six doses, 2.5 to 15 mg, taken once a week. The label's rule is four weeks at 2.5 mg, then 2.5 mg steps with at least four weeks on each, to a maintenance dose of 5, 10 or 15 mg. In SURMOUNT-1 those three doses lost 15.0, 19.5 and 20.9 percent of body weight over 72 weeks. Direct from Lilly each rung has a price, $299 at 2.5 mg rising to $699 at 10 mg and above, so the chart below carries the dose, the rule, the trial result and the bill in one place, plus the vial and KwikPen concentrations for anyone measuring in units.
- Mounjaro for weight loss, and why Zepbound exists
Mounjaro is tirzepatide approved for type 2 diabetes. Zepbound is the same molecule from the same maker, approved for weight management, and it goes to the same 15 mg. So unlike Ozempic and Wegovy, there is no dose ceiling pushing you from one to the other: the reason people move is coverage and cash price, not strength. Using Mounjaro for weight is off-label and a prescriber's decision. In the one head-to-head trial, tirzepatide beat semaglutide, 20.2% mean body-weight loss at 72 weeks against 13.7%.
Find more like it
Side effectsDose changeWeigh-in and resultsFood, protein and eatingFood noise and cravingsCost and insuranceExercise and strengthHow it worksNauseaVomiting
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