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GLP-1 TV · Patient story · views checked Oct 2026

WEGOVY - Week 1-2 | Weight Loss, Side Effects, Type I Diabetes

Patient storyNikki Kesten18,748 views10:51Mar 2022

Our summary

Nikki, who blogs as Lipstick and Brunch, shares her first two weeks on Wegovy. She says she has type 1 diabetes, exercises daily and follows a high protein, low sugar, low carb diet. She explains that she has been working on weight loss and fitness since 2019 but saw no change on the scale after adding strength training and tracking her food. Her endocrinologist suggested Wegovy, saying it could improve her A1C, her blood sugars and how well her insulin works, and that she would most likely lose weight. She describes it as semaglutide, the same ingredient as Ozempic, and says it works mainly by suppressing appetite. She cites doctors who discussed a study in which people on Wegovy lost an average of 15.2 percent of their body weight.

One person's experience, in their words. Not medical advice.

What else the video covers

On side effects, she says she was frightened by the list and by what she saw on YouTube, where nausea and constipation came up most. Her own experience was nausea only. After her first dose she felt nauseous and bloated within three hours, and after the second she felt nauseous the next day, though she says it was not horrible. She says she never vomited and had no stomach aches, apart from one day when she ate a larger meal than she should have. She reports being full after about half of her usual portions and now eats smaller meals.

She started on February 18th, took her second dose on the 25th, and takes one dose a week on Fridays. She reports losing two pounds after week one and one more pound after week two, three pounds in total. Her syringes contain 0.25 milligrams, and she says the next box will be 0.5 milligrams, a dose she has heard makes some people very sick. She plans another video after her last dose of this box on the 11th.

Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.

Takeaways

The main points, in the order they come up. Tap a time to play from there.

  1. 1:03 She says Wegovy contains semaglutide, the same ingredient as Ozempic, and that her endocrinologist suggested it after her weight did not change despite diet and exercise.
  2. 2:34 Her doctor told her Wegovy could improve her A1C and blood sugars and help her insulin work better, with weight loss likely.
  3. 4:39 She reports nausea as her only side effect, with bloating after the first dose and no vomiting or stomach aches.
  4. 5:44 She says the appetite suppression cut her food intake roughly in half, leaving her full on small portions.
  5. 7:17 She started February 18th with one dose each week and reports losing two pounds in week one and a third pound in week two.
  6. 8:51 She says the next box is 0.5 milligrams per dose instead of 0.25 milligrams, and she hopes it does not make her very sick.

Key moments

From the creator's own chapters. Tap one to play from there.

  1. 0:00 Introduction to Wegovy
  2. 1:03 Why I chose Wegovy
  3. 3:07 How Wegovy works
  4. 4:25 Side effects and experience
  5. 7:18 Weight loss results
  6. 8:38 Next steps and conclusion

What the video says

As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.

Medication
Wegovy
Point in the journey
Week 1
Side effects mentioned
nausea, vomiting and bloating
Who is speaking
Patient

Questions this video answers

How much weight did she lose in the first two weeks on Wegovy?

She says she lost two pounds after the first week and another pound after the second, for three pounds in total. She notes she was also exercising and eating healthy during this time.

What side effects did she have on Wegovy?

She reports nausea as her only side effect. She felt nauseous and bloated within three hours of the first dose and nauseous the day after the second. She says she never vomited and had no stomach aches except after one oversized meal.

Why did her doctor suggest Wegovy for type 1 diabetes?

She says her endocrinologist told her it could improve her A1C and blood sugars and help her insulin work better. The doctor also said she would most likely lose weight, since insulin use and hormones can make weight loss harder.

What Wegovy dose does she start on?

She says each syringe in her first box is 0.25 milligrams, taken once a week on the same day. She says the next box has a higher 0.5 milligram dose.

Videos on the same question

The closest videos in the library by what is said in them, not by title.

Read next

Our guides closest to what this video covers, with prices checked weekly.

  • Wegovy side effects, and why the top of the ladder is different

    Wegovy's side effects are semaglutide's side effects: nausea, vomiting, diarrhoea and constipation, worst in the first weeks and after each dose increase. What makes Wegovy different from Ozempic is not the molecule but the destination. Wegovy is dosed for weight management, climbing to 2.4 mg with a 7.2 mg high-dose strength above it, and dose is the main driver of how pronounced the gastrointestinal effects get. It also carries a boxed warning for thyroid C-cell tumour risk. One useful fact while you decide whether to push through: Novo's self-pay price is flat across every pen dose, so a slower climb costs a brand patient nothing.

  • Mounjaro vs Ozempic, and the trial everyone quotes about it

    Mounjaro is tirzepatide and Ozempic is semaglutide: different molecules, not two brands of the same drug. Both are approved for type 2 diabetes, and the weight-loss versions are Zepbound and Wegovy. In the one head-to-head trial, SURMOUNT-5, tirzepatide produced 20.2% mean body-weight loss at 72 weeks against semaglutide's 13.7%. The detail almost every page omits: that trial dosed semaglutide to 2.4 mg in people without diabetes, which is the Wegovy range. Ozempic tops out at 2 mg. The famous result did not test Ozempic's dose range.

  • Semaglutide for weight loss: which version, and what each costs

    Semaglutide is the molecule. For weight loss the FDA-approved version is Wegovy, sold as a weekly pen and a daily tablet. Ozempic is the same molecule approved for type 2 diabetes, so using it for weight is off-label. Compounded semaglutide is the same molecule from a compounding pharmacy, is not FDA-approved, and is what most cash buyers actually take because it costs a fraction of the brand. All three produce the same side effects. What differs is the approval, the oversight and the price.

Find more like it

Side effectsDose changeWeigh-in and resultsFood, protein and eatingExercise and strengthThe trialsNauseaVomitingBloating

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