PriceTracker GLP-1

Key findings

  1. Part D gross spending on GLP-1 drugs reached $27.5 billion in 2024, 3.9 times the $7.0 billion of 2020 and 24% above 2023.
  2. Ozempic alone accounted for $13.0 billion (47%), across 1.95 million beneficiaries.
  3. Semaglutide brands (Ozempic, Rybelsus, Wegovy) totaled $15.2 billion; tirzepatide brands (Mounjaro, Zepbound) $6.3 billion.
  4. Part D paid for 21.83 million GLP-1 claims in 2024, against 5.82 million in 2020.
  5. These are gross costs before manufacturer rebates, which CMS does not publish per drug.

The numbers, to scale

Part D spending on GLP-1 drugs by year
2020: $7.0 billion across 7 brands$7.0B20202021: $10.0 billion across 7 brands$10.0B20212022: $13.9 billion across 8 brands$13.9B20222023: $22.2 billion across 9 brands$22.2B20232024: $27.5 billion across 11 brands$27.5B2024

Sum of every GLP-1 brand's total spending. Source: CMS Medicare Part D Spending by Drug, updated June 25, 2026.

Spending by brand, 2024
  1. Ozempic$13.0B
  2. Mounjaro$6.3B
  3. Trulicity$5.5B
  4. Rybelsus$1.9B
  5. Wegovy$301M
  6. Bydureon Bcise$215M
  7. Victoza 3-Pak$203M
  8. Victoza 2-Pak$77.8M
  9. Liraglutide$48.1M
  10. Byetta$15.9M
  11. Zepbound$387K

Each brand's total Part D spending, all manufacturers combined.

Every GLP-1 brand in Part D (11), highest 2024 spending first

Medicare Part D spending on GLP-1 drugs, 2020 to 2024
BrandGeneric20202024 spendingClaimsBeneficiariesPer beneficiary
OzempicSemaglutide$1,455,812,267$12,970,296,34710,417,1821,952,637$6,642
MounjaroTirzepatideNone reported$6,336,942,6415,105,397894,581$7,084
TrulicityDulaglutide$3,284,873,062$5,454,134,7254,305,141788,716$6,915
RybelsusSemaglutide$73,444,409$1,890,082,0261,251,733309,993$6,097
WegovySemaglutideNone reported$301,283,291211,57552,961$5,689
Bydureon BciseExenatide Microspheres$266,160,951$215,354,678178,93138,059$5,658
Victoza 3-PakLiraglutide$1,545,815,415$203,063,050181,06862,754$3,236
Victoza 2-PakLiraglutide$349,476,159$77,832,721108,52141,126$1,893
LiraglutideLiraglutideNone reported$48,095,82462,25424,405$1,971
ByettaExenatide$47,676,632$15,877,48011,7123,043$5,218
ZepboundTirzepatideNone reported$387,343353245$1,581

"None reported" marks years a brand had no Part D spending reported (it was not yet approved or not covered). The export carries every year. All 11 rows, with every column, are in the CSV and JSON.

How the number is computed

Sum of "Total Spending" for each year across every GLP-1 brand's "Overall" row (all manufacturers combined) in CMS's Medicare Part D Spending by Drug dataset, data year 2024.

Included

  • Brands: Ozempic, Mounjaro, Trulicity, Rybelsus, Wegovy, Bydureon Bcise, Victoza 3-Pak, Victoza 2-Pak, Liraglutide, Byetta, Zepbound.

Excluded

  • Insulin combinations: Soliqua (insulin glargine and lixisenatide); Xultophy (insulin degludec and liraglutide).
  • Beneficiaries are not summed across brands: one person can fill two brands in a year.

Read it with care

  • Spending is gross drug cost (what plans and patients paid pharmacies), before manufacturer rebates and discounts.
  • Medicare Part D does not cover drugs prescribed for weight loss alone; most of this spending is for type 2 diabetes, with Wegovy and Zepbound covered for other approved uses.
  • CMS flags a brand-year as an outlier when its average spending per unit looks unusual: Wegovy 2023.

Receipts

2 sources · read October 4, 2026

  1. 01read

    Five calendar years per brand: total spending, claims, dosage units, beneficiaries.

    CMS, Medicare Part D Spending by Drug, data year 2024 (data.cms.gov), updated June 25, 2026
  2. 02read

Cite this

Free to reuse under CC BY 4.0: quote the number, credit PriceTracker GLP-1 with a link, and name the federal source. The underlying records are public; our counts, matching and files are the work you are crediting.

Citation (APA)
PriceTracker GLP-1. (2026, October 4). Medicare Part D spending on GLP-1 drugs, 2020 to 2024 [Data set]. Based on Centers for Medicare & Medicaid Services data, cms data updated June 25, 2026. https://pricetrackerglp1.com/data/medicare-part-d-glp1-spending
Sentence with link (HTML)
<p>Medicare Part D spent $27.5 billion on GLP-1 drugs in 2024, up from $7.0 billion in 2020, according to CMS Medicare Part D Spending by Drug data updated June 25, 2026. Source: <a href="https://pricetrackerglp1.com/data/medicare-part-d-glp1-spending">PriceTracker GLP-1</a> (CC BY 4.0).</p>
Data files
https://pricetrackerglp1.com/data/medicare-part-d-glp1-spending.csv
https://pricetrackerglp1.com/data/medicare-part-d-glp1-spending.json