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GLP-1 TV · Patient story · views checked Oct 2026

Finally took 5mg shot of Zepbound (Mounjaro)/ Week 8 review/ new side effects/EliLillly BIG News

Patient storySimply Sunshine | Weight Loss Journey25,425 views33:18Apr 2024

Our summary

Cheryl, who runs the Simply Sunshine channel, gives her week eight update on taking Zepbound (tirzepatide) for weight loss. She says she has used the 2.5 mg pen for two months because higher doses were hard to find. The first six weeks went well, but in the last two weeks she felt less hunger suppression and says the food noise began to return. On April 25, 2024 she took her ninth shot a day early, using two 2.5 mg pens to make 5 mg, which she says her pharmacist told her is fine. She injected into her stomach rather than her thigh, and for the first time cleaned the skin with alcohol. She felt a burning sensation and guesses the alcohol swab caused it, not the medication.

One person's experience, in their words. Not medical advice.

What else the video covers

She reports a plateau at 20 lb lost and says she raised her calories to 1,400. She also says she gained weight after eating dessert around 9:30 at night, so she plans to stop eating by 7:30. On side effects, she describes mostly stomach upset after certain foods and alcohol, little constipation, and some tiredness. She wonders whether allergy season, menopause, a busy schedule and her age play a part. About ten hours after the 5 mg dose she had not noticed hunger suppression or new side effects, and she asks viewers to share their own experiences moving between doses.

She describes trouble getting a three-month supply through her insurance and says her doctor's office told her it does not usually write those scripts. She says she is number 10 on a Walmart waiting list. She also discusses news that Eli Lilly bought a plant in Wisconsin that makes similar pens, with production for Lilly expected at the start of next year, which she puts at 6 to 8 months away. She advises new patients to keep calling pharmacies and says 2.5 mg seems easiest to find.

Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.

Takeaways

The main points, in the order they come up. Tap a time to play from there.

  1. 1:04 Cheryl explains that Zepbound and Mounjaro are the same medication, tirzepatide, sold under different names for obesity and type 2 diabetes.
  2. 4:00 She says two months on the 2.5 mg pen worked well for about six weeks, then hunger suppression faded and food noise returned.
  3. 8:00 She reports a plateau at 20 lb lost, raised her calories to 1,400, and plans to stop eating by 7:30 p.m.
  4. 11:41 She took two 2.5 mg shots for a 5 mg dose in her stomach, used an alcohol swab for the first time, and felt burning she attributes to the alcohol.
  5. 14:14 She describes mild side effects, mainly occasional stomach upset and tiredness, and questions whether allergies or menopause contribute.
  6. 27:30 She shares news of Eli Lilly buying a Wisconsin plant, expected to produce for Lilly at the start of next year, and advises newcomers to keep calling pharmacies.

Key moments

From the creator's own chapters. Tap one to play from there.

  1. 0:00 Introduction to journey
  2. 3:55 Zepbound and food noise
  3. 6:59 Week eight recap
  4. 11:33 Increasing dose to 5mg
  5. 14:07 Side effects management
  6. 22:22 Day one with 5mg dose
  7. 25:13 Shortage and doctor issues
  8. 28:53 Tips and closing thoughts

What the video says

As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.

Medication
Zepbound and Mounjaro
Doses mentioned
5 mg
Point in the journey
Week 8
Side effects mentioned
nausea, fatigue and headache
Who is speaking
Patient

Questions this video answers

Can you take two 2.5 mg Zepbound pens to make a 5 mg dose?

Cheryl says she took two 2.5 mg shots to make 5 mg because she could not find a 5 mg pen. She says her pharmacist told her this is fine and that three 2.5 mg pens could equal 7.5 mg. This is her account, not medical advice.

Why does a Zepbound injection burn?

Cheryl says she had never felt her shot until the morning she used an alcohol swab, when both injections burned for about 2 minutes. She guesses the alcohol, not the medication, causes the burning, and says this is only her guess.

Did the Zepbound 2.5 mg dose stop working for her?

She says the first six weeks on 2.5 mg were good, then the last two weeks brought less hunger suppression and returning food noise. She was at a 20 lb loss and had hit a plateau at week eight.

What did Eli Lilly announce about the Zepbound shortage?

According to Cheryl, Eli Lilly purchased a plant in Wisconsin that already makes similar pens. She says it will not produce for Lilly until the beginning of next year, which she describes as 6 to 8 months away.

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About Simply Sunshine | Weight Loss Journey

Patient story, 7.1K subscribers. 6 of their videos are in GLP-1 TV, 150K views between them, mostly on Zepbound, Mounjaro, Wegovy pill.

Every Simply Sunshine | Weight Loss Journey video

Read next

Our guides closest to what this video covers, with prices checked weekly.

  • Mounjaro for weight loss, and why Zepbound exists

    Mounjaro is tirzepatide approved for type 2 diabetes. Zepbound is the same molecule from the same maker, approved for weight management, and it goes to the same 15 mg. So unlike Ozempic and Wegovy, there is no dose ceiling pushing you from one to the other: the reason people move is coverage and cash price, not strength. Using Mounjaro for weight is off-label and a prescriber's decision. In the one head-to-head trial, tirzepatide beat semaglutide, 20.2% mean body-weight loss at 72 weeks against 13.7%.

  • Mounjaro side effects: the label's numbers by dose, the low blood sugar risk, and how tirzepatide compares at weight-loss doses

    On Mounjaro's own label, the common side effects are stomach ones and they rise with the dose: nausea in 12, 15 and 18 percent of people at 5, 10 and 15 mg against 4 percent on placebo, diarrhea 12 to 17 against 9, and any gastrointestinal reaction in 37 to 44 percent against 20. Most of it happens while the dose is being raised and fades. Low blood sugar is rare on Mounjaro alone and is mainly a risk when it is added to insulin or a sulfonylurea. Below: the full table, the rare warnings, and why Zepbound's numbers for the same molecule look higher.

  • What is Zepbound? Tirzepatide explained: what it treats, how it works, and what it costs

    Zepbound is Eli Lilly's brand of tirzepatide, a once-weekly injection that acts on two hormone receptors, GIP and GLP-1. The FDA label approves it, with diet and exercise, for weight reduction in adults with obesity or overweight plus a weight-related condition, and for moderate to severe obstructive sleep apnea in adults with obesity. In the SURMOUNT-5 trial it produced 20.2% average weight loss at 72 weeks against 13.7% for semaglutide. Lilly sells it self-pay from $299 a month.

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Side effectsDose changeWeigh-in and resultsFood, protein and eatingFood noise and cravingsInjection techniqueCost and insuranceAlcoholStopping and maintenanceNausea

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