GLP-1 TV · Patient story · views checked Oct 2026
Week 1 - Weight Loss Injection Journey - An Overweight Runners Point of View
Our summary
In this video, Freddy, a runner who says they have run constantly for 2 years and struggled with dieting, reports on the first week of taking Mounjaro (the captions spell it "mangaro"). They say they thought about it for about a year before deciding. According to the video, they started at 18 stone 6 and took the first injection on a Saturday, with their wife administering it from a pen used straight from the fridge. They describe it as painless.
One person's experience, in their words. Not medical advice.
Where tirzepatide costs least today
The three cheapest partner programs for tirzepatide, all in per month, checked weekly. Brand Mounjaro and compounded versions are different products; each row says which it is.
What else the video covers
Freddy says the effects started about 3 hours after the first dose, and that their appetite largely disappeared. They describe constant thoughts about food going quiet and say they now have to remind themselves to eat, which gives them room to pick healthier options. They list side effects as mild heartburn or indigestion lasting about 3 days and a headache for the first two or 3 days, which they put down to sugar withdrawal. They also report that their resting heart rate rose by about four or five beats per minute and that their heart rate ran high on easy runs. They say they are not worried but are watching it.
Freddy says they weigh daily using a Wi-Fi scale that sends data to an app, and they review the weekly average. They report losing 8 pounds in week one, going from 18 stone 6 to 17 stone 12, and acknowledge that early loss may be mostly water. They say the dose was 2 and a half milligrams. They close by describing a harder week ahead, with work travel from the northeast of England to London and Belgium, service station food choices, and the lead-up to a 5K personal best attempt.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 0:32 Freddy says they chose to try the medication after struggling with dieting despite 2 years of running.
- 1:33 Freddy reports that appetite dropped within about 3 hours of the first injection and that constant thoughts about food went quiet.
- 3:09 Freddy says their wife gave the injection, using the pen straight from the fridge, and that it was painless.
- 7:16 Freddy lists mild heartburn for about 3 days and early headaches as the side effects they noticed.
- 7:46 Freddy reports a resting heart rate increase of about four or five beats per minute and higher heart rate on easy runs.
- 11:50 Freddy says they lost 8 pounds in week one, going from 18 stone 6 to 17 stone 12.
Key moments
From the creator's own chapters. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Point in the journey
- Week 1
- Side effects mentioned
- heartburn or reflux
- Who is speaking
- Patient
Questions this video answers
How much weight can you lose in the first week of Mounjaro?
Freddy reports losing 8 pounds in week one, from 18 stone 6 to 17 stone 12, on a 2 and a half milligram dose. They note they were told the first week often includes a lot of water weight.
What side effects did Freddy have in the first week of Mounjaro?
Freddy says they had mild heartburn or indigestion for about 3 days and a headache for the first two or 3 days, which they attribute to sugar withdrawal. They also report a resting heart rate increase of about four or five beats per minute.
How quickly did Mounjaro reduce appetite for Freddy?
Freddy says the effect kicked in after about 3 hours following the first injection. They describe losing the desire to eat and having to remind themselves to have meals.
Does Mounjaro affect heart rate when running?
Freddy reports that their heart rate was higher than usual on easy runs during week one and that their resting heart rate rose by about four or five beats per minute. They say they are not concerned but are monitoring it, and they make no medical claims.
Videos on the same question
The closest videos in the library by what is said in them, not by title.
Mounjaro Weight Loss Results - Week 1 & 2 (Zepbound)Phil, who runs the channel Phill Double L, looks back at the first two weeks of his Mounjaro treatment, which he says began four months before filming.
MOUNJARO UPDATE | weight loss so far, addressing negative comments & how I’m feelingHelen, who runs the channel Babbling by the Brook, gives a five-week update on taking Mounjaro.
I Tried Mounjaro For 3 Months Here's What HappenedIn this video from the Man Does Midlife channel, a man describes roughly 11 weeks on Mounjaro.
Mounjaro Turned Off My Food Noise — I Lost 80 lbs!In this episode of The Downsized Dish, host Lorraine Durham interviews Joe, a Mounjaro user from Nottingham in the UK who runs the channel Joe's Sleep and Slim Down Journey.
Read next
Our guides closest to what this video covers, with prices checked weekly.
- Mounjaro for weight loss, and why Zepbound exists
Mounjaro is tirzepatide approved for type 2 diabetes. Zepbound is the same molecule from the same maker, approved for weight management, and it goes to the same 15 mg. So unlike Ozempic and Wegovy, there is no dose ceiling pushing you from one to the other: the reason people move is coverage and cash price, not strength. Using Mounjaro for weight is off-label and a prescriber's decision. In the one head-to-head trial, tirzepatide beat semaglutide, 20.2% mean body-weight loss at 72 weeks against 13.7%.
- Mounjaro vs Rybelsus: a weekly shot against a pill Novo is replacing
Mounjaro is tirzepatide, a once-weekly injection; Rybelsus is semaglutide, a once-daily tablet. Both are type 2 diabetes drugs, and they have never been tested against each other. The bigger news for anyone choosing: Novo Nordisk says Rybelsus is being replaced by the Ozempic pill, which needs a new prescription. Paying cash, Mounjaro starts at $499 a month at LillyDirect, and Novo sells the Ozempic pill, not Rybelsus, at $149 to $299 a month.
- Mounjaro dosage chart: the label's schedule, every pen and vial, and what each dose costs
Mounjaro starts at 2.5 mg injected once a week. If more blood sugar control is needed, the dose goes up in 2.5 mg steps after at least four weeks on the current dose, to a maximum of 15 mg a week for adults and 10 mg for children 10 and older. Lilly sells every strength self-pay starting at $499 a month, so on the brand the price does not climb with the dose.
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Side effectsWeigh-in and resultsFood, protein and eatingFood noise and cravingsInjection techniqueHeartburn or reflux
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