GLP-1 TV · Patient story · views checked Oct 2026
Weight Loss Update - 18 Months On Mounjaro
Our summary
Caroline, who posts as Mrs M on an over-50 lifestyle channel, gives an update after almost 18 months on Mounjaro. She says she is still on 10 mg, that prices have risen a lot, and that she is fortunate to be able to afford it. Her weight loss has stalled around the four stone mark she reached at her last update, apart from a few pounds gained and lost again around a 10-day all-inclusive holiday in January. She says she has decided to try a single 12.5 mg pen, five doses, for about a month and then return to 10 mg, hoping for a bit more appetite suppression. She describes her eating habits as hugely changed: less binge eating, less thinking about food, and no trouble leaving food on the plate.
One person's experience, in their words. Not medical advice.
Where tirzepatide costs least today
The three cheapest partner programs for tirzepatide, all in per month, checked weekly. Brand Mounjaro and compounded versions are different products; each row says which it is.
What else the video covers
She also talks about a sponsored section on the Simple app, which she has trialled this month. She describes it as a personalised plan with no calorie counting, food logging by photo, voice or typing, workouts, and an AI coach called Avo, and she gives a discount code. The rest of the video answers viewer questions from Instagram.
In the answers, she says she felt appetite restriction within hours of her first injection on 2.5 mg, and stayed on that dose for 2 months. She uses the extra fifth dose from each pen with syringes bought online. She reports only occasional nausea and stomach pain, about once every couple of months, plus constipation that she manages with psyllium husk. She says her arthritis pain is much better, she has not noticed muscle loss or hair thinning, and her doctor expects her to come off blood pressure medication soon. She plans to taper down through the doses when she stops, and she keeps her goal weight private.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 1:40 She says she is on 10 mg of Mounjaro, her weight loss has stalled near the four stone mark, and prices have risen sharply.
- 2:30 She plans to take one 12.5 mg pen (five doses) for about a month, then go back to 10 mg, hoping for a small boost.
- 5:41 She describes trialling the sponsored Simple app, which offers a personalised plan, food logging, workouts and an AI coach.
- 7:53 She says she uses the fifth dose left in each pen, extracted with syringes bought online, because of the cost of Mounjaro.
- 10:17 She reports only occasional nausea and stomach pain, constipation managed with psyllium husk, and much less arthritis pain.
- 17:30 She says she took her longest break between doses (14 days) on holiday, following her provider's guidance, and she plans to taper off slowly.
Key moments
Where the talk turns, found in the captions. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- Mounjaro
- Doses mentioned
- 2.5 mg, 10 mg and 12.5 mg
- Point in the journey
- Month 18
- Side effects mentioned
- loose skin or face changes and muscle loss
- Who is speaking
- Patient
Questions this video answers
Why is she increasing to 12.5 mg of Mounjaro after 18 months?
Caroline says her weight loss has stalled around the four stone mark and she wants a small push to start losing again. She plans to use one 12.5 mg pen for five doses, then return to 10 mg, though she says she may change her mind.
Does she use the fifth dose in a Mounjaro pen?
She says yes. She explains that some liquid remains after the four standard doses, and she draws it out with syringes bought online. She says it is almost essential given the cost, and that it feels no different to her.
What side effects does she report on Mounjaro?
She says she gets nausea and upper stomach pain only about once every couple of months, and not badly in the last 12 months. She also reports constipation, which she says she manages with two psyllium husk capsules a day.
How does she plan to come off Mounjaro?
She says she plans to taper back down through the doses rather than stopping suddenly. She says she is not yet at that stage and tries not to think too far ahead.
Videos on the same question
The closest videos in the library by what is said in them, not by title.
MOUNJARO UPDATE | weight loss so far, addressing negative comments & how I’m feelingHelen, who runs the channel Babbling by the Brook, gives a five-week update on taking Mounjaro.
Mounjaro Month 4 Update - My Weight Loss Drug JourneyIn this month four update, Caroline, a creator who makes over 50 lifestyle videos, recaps her fourth month on Mounjaro.
Mounjaro NO MORE?! 😳 Insurance Cut Me Off… What Happens Now?Chase, a creator who says she has had bariatric surgery, follows her first year on GLP-1 medication from late October 2025 to late January 2026.
Mounjaro Update: What Happens When You’re Forced to Stop (My Honest Story)The creator of the Mounjaro Journey channel says he had to stop Mounjaro for a little over two weeks because he could not afford the next pen after a price increase.
12 Months on Mounjaro- I'm DoneDr Emma Anders marks 12 months on Mounjaro and says her own weight loss phase is finished.
What Happened When I Stopped Mounjaro?Lauren Brazee answers viewer questions from her Instagram about coming off Mounjaro.
Read next
Our guides closest to what this video covers, with prices checked weekly.
- The best GLP-1 for weight loss, ranked by the evidence and then by the bill
By weight lost, the order is settled: tirzepatide (Zepbound) first at 20.2% in the only head-to-head, then semaglutide 7.2 mg (Wegovy HD) at 18.7%, then semaglutide 2.4 mg (Wegovy) at 13.7% to 15.6%, then the pills. By what you pay, the order nearly inverts: compounded semaglutide from $69 a month, the Wegovy tablet from $149, Wegovy pen $349, Zepbound $299 to $699 by dose. The best one is where those two lists meet for your budget and your plan.
- Mounjaro for weight loss, and why Zepbound exists
Mounjaro is tirzepatide approved for type 2 diabetes. Zepbound is the same molecule from the same maker, approved for weight management, and it goes to the same 15 mg. So unlike Ozempic and Wegovy, there is no dose ceiling pushing you from one to the other: the reason people move is coverage and cash price, not strength. Using Mounjaro for weight is off-label and a prescriber's decision. In the one head-to-head trial, tirzepatide beat semaglutide, 20.2% mean body-weight loss at 72 weeks against 13.7%.
- How to get Mounjaro: the diabetes route, and why the weight route is a different box
Mounjaro is approved for type 2 diabetes in adults and children from 10, and Lilly's own site says it is not a weight-loss drug. With a diabetes diagnosis, any prescriber can write it and a commercial plan that covers it brings it to $25 with Lilly's card. Without diabetes, a prescriber can write it off-label, but no insurer will cover it and LillyDirect self-pay starts at $499 a month, against a list price of $1,112.16 per fill. The same tirzepatide in the Zepbound box is approved for weight, plan-coverable, and sold direct for $299 to $699.
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