GLP-1 TV · Patient story · views checked Oct 2026
Zepbound Week 61: The Dose Was the Problem
Our summary
In this week 61 update, the creator says she gained 13.8 pounds in 11 days after her Zepbound dose was lowered from 5 milligrams to 2.5 milligrams. She recaps her course so far: 18 pounds lost in the first four weeks on 2.5 milligrams, which a DEXA scan showed was mostly muscle, then weeks five through 56 on 5 milligrams with no side effects and no food noise. She says she reached her 135 pound goal in 26 weeks and has been in maintenance for 35 weeks.
One person's experience, in their words. Not medical advice.
Where Zepbound costs least today
The three cheapest partner programs for Zepbound, all in per month, checked weekly. Brand Zepbound and compounded versions are different products; each row says which it is.
What else the video covers
She walks through her weigh-ins. She reports 128 pounds on April 6 and 134 pounds on April 13. She then lists daily weights that peaked at 141.8 pounds on a Thursday and came back down to 134.4 pounds on the day of recording. She says she changed nothing except the dose: same workouts, a whole food plant-based diet at about 1,800 calories a day, and a gallon of water daily. She also mentions hormone replacement therapy, with an estradiol increase and new testosterone, and says she does not know whether stress over her pet rabbit, the dose change, or both explain the gain. She says she had food noise on two days but did not act on it.
She encourages viewers to hold steady if they are doing the right things, to check with a dietitian or doctor about calories, and to choose simple, easy-to-do exercise. She also describes her strength program, her Instagram and Facebook posts, a daily mindset video series, and her Monday live streams.
Our summary of what is said, in our words. Doses, results and prices are the speaker’s, not advice.
Takeaways
The main points, in the order they come up. Tap a time to play from there.
- 0:00 She says she gained 13.8 pounds in 11 days, after 61 weeks on Zepbound with 18 pounds lost in the first four weeks on 2.5 milligrams, mostly muscle according to a DEXA scan.
- 1:34 She says the only change was moving from 5 milligrams down to 2.5 milligrams, followed by a stressful event, and she lists her daily weights from 138 up to 141.8 and back to 134.4 pounds.
- 3:06 She says her workouts, whole food plant-based diet of about 1,800 calories, and water intake stayed the same, and she lists her hormone replacement therapy and supplements.
- 6:49 She says food noise returned on two days that week, and that she noticed it without acting on it.
- 8:53 She names the 15-Minute Standing Strength Series she follows and says walking, stretching, yoga, or home workouts can work if the gym is a barrier.
- 14:45 She closes by saying to trust the process and keep tracking, because she sees this as a lifestyle change that takes time.
Key moments
From the creator's own chapters. Tap one to play from there.
What the video says
As stated in the video, not checked by us. Doses and results are the speaker’s, not advice.
- Medication
- Zepbound
- Doses mentioned
- 2.5 mg
- Point in the journey
- Week 61
- Who is speaking
- Patient
In their words
"Do not let the scale dictate your progress"
Questions this video answers
Can lowering the Zepbound dose cause weight gain?
The creator says she gained 13.8 pounds in 11 days after moving from 5 milligrams to 2.5 milligrams, with no other changes to her routine. She says she cannot tell whether the dose change, stress, or both caused it, and that her weight was heading back down by the end of the video.
What should you do if the scale jumps suddenly on Zepbound?
She says she kept the same workouts, calories, and water intake and did not make a bunch of changes. She says she would have contacted a professional if the gain reached about 20 pounds, and she advises not letting the scale dictate progress.
Did she have side effects on Zepbound 5 milligrams?
She says that on 5 milligrams for weeks five through 56 she had no food noise and no side effects. She also reports no GI issues, nausea, tiredness, or hair thinning.
What does she say to do if food noise comes back?
She says food noise returned on two days for her and she did not act on it. She suggests pushing through if it comes right before the next shot, making sure you are eating enough, and talking to a dietitian or doctor about calories.
Videos on the same question
The closest videos in the library by what is said in them, not by title.
6 Months on a GLP-1: DEXA Scan & Metabolism Results RevealedLenore, who describes herself as a nutritionist and nutrition coach, reports on six months of using a GLP-1, specifically Zepbound.
Zepbound - 2 week update on 7.5mgElise, who posts as For Elise Desiree, says she has moved up to 7.5mg of Zepbound after about six months on the medication.
I Paused Zepbound for 30 days..Here's What HappenedIn this video from December 2025, a nutritionist and health coach who also takes a GLP-1 describes what happened when she stopped Zepbound for about four weeks.
1 YEAR on the LOWEST DOSE of ZEPBOUND?? The return of food noise / weightloss before and after /glp1Kristen, who posts as Feed Crissy, marks one year on Zepbound with an update on her weight, her eating and how she feels about the medication.
I've Lost 30 Pounds in 4 Months! Weaning Off Zepbound Continues ✨Nurse Sabrina Clayton says she is weaning off Zepbound by injecting every other week instead of weekly until her remaining supply runs out.
Read next
Our guides closest to what this video covers, with prices checked weekly.
- Zepbound dosage chart: every tirzepatide dose, the escalation rule, what each rung lost in the trial, and what it costs
Zepbound has six doses, 2.5 to 15 mg, taken once a week. The label's rule is four weeks at 2.5 mg, then 2.5 mg steps with at least four weeks on each, to a maintenance dose of 5, 10 or 15 mg. In SURMOUNT-1 those three doses lost 15.0, 19.5 and 20.9 percent of body weight over 72 weeks. Direct from Lilly each rung has a price, $299 at 2.5 mg rising to $699 at 10 mg and above, so the chart below carries the dose, the rule, the trial result and the bill in one place, plus the vial and KwikPen concentrations for anyone measuring in units.
- Mounjaro for weight loss, and why Zepbound exists
Mounjaro is tirzepatide approved for type 2 diabetes. Zepbound is the same molecule from the same maker, approved for weight management, and it goes to the same 15 mg. So unlike Ozempic and Wegovy, there is no dose ceiling pushing you from one to the other: the reason people move is coverage and cash price, not strength. Using Mounjaro for weight is off-label and a prescriber's decision. In the one head-to-head trial, tirzepatide beat semaglutide, 20.2% mean body-weight loss at 72 weeks against 13.7%.
- How long do Ozempic, Wegovy and Zepbound take to work? The label calendar and the trial timepoints
GLP-1s act from the first dose, but the labels start low on purpose and step up every 4 weeks, so most people do not reach a full dose for 3 to 5 months. Each dose reaches steady levels in the blood after about 4 to 5 weeks. In the trials, people averaged 10.6% weight loss after 20 weeks of Wegovy's escalation and 20.9% after 36 weeks of Zepbound, with the full trial results at 68 to 72 weeks. For type 2 diabetes, Ozempic's A1C results were measured at week 30.
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