The rest of the deal
| SkinnyRx | TMates | |
|---|---|---|
| Lowest price, all in | $199/mosemaglutide injection, compounded, billed monthly | $158/mosemaglutide injection, compounded, 12-month plan, $1,896 up front |
| Month to month | $199/mofrom, semaglutide injection, compounded | $249/mofrom, semaglutide injection, compounded |
| Membership fee | None | None |
| Consultation | Included | Included |
| What it sells |
|
|
| Oral option | Semaglutide, oral, compounded; Tirzepatide, oral, compounded | No |
| Brand-name drugs | No, compounded only | No, compounded only |
| Insurance | Cash only | Accepted |
| States served | 48 states | 45 states |
| Shipping | Included | Included |
| Cancellation | Cancel anytime | Cancel anytime |
| Clinicians | U.S.-licensed doctors who turn around prescription reviews in 24-48 hours | Licensed clinicians paired with text-message coaching and digital check-ins |
| Price by dose | No dose-level prices published, so no per-mg figure | No dose-level prices published, so no per-mg figure |
| Trustpilot | 4.8 of 55,340 reviews on Trustpilot | 3.2 of 51 reviews on Trustpilot, too few to read much into |
| Prices last read | October 2026 | October 2026 |
Ratings are shown as published and never change our order, which is by price only. We do not print a cost per 1% of weight lost: the published trials measured brand-name drugs, not these programs’ compounded versions, so the figure would borrow a result neither product earned.
Who each one fits
Pick SkinnyRx if
- you want to pay month to month: from $199, against $249
- you want its lowest price without prepaying (TMates's lowest needs 12 months up front)
- you want a GLP-1 you do not inject
Pick TMates if
- you want the lower semaglutide price: $158 a month on a 12-month plan, against $199 at SkinnyRx
- you want the lower tirzepatide price: $167 a month on a 12-month plan, against $299 at SkinnyRx
- you want to pay through insurance
What each includes, and the catch
SkinnyRx
- Consultation: included
- Shipping: included
- Membership: none
- Cancel anytime
Worth knowing
- You'll pay cash: they don't run anything through insurance
- Only compounded formulas here; brand-name versions aren't offered
TMates
- Consultation: included
- Shipping: included
- Membership: none
- Cancel anytime
Worth knowing
- It's a younger platform, so independent reviews remain sparse
- You'll need to enroll before the full program details are confirmed
Common questions
Which is cheaper, SkinnyRx or TMates?
Neither is cheaper across the board: of 2 like-for-like prices, SkinnyRx is lower on 1, TMates on 1. The lowest price at SkinnyRx is $199 a month month to month; at TMates it is $158 a month on a 12-month plan ($1,896 up front). Both all in, membership fees included.
Do SkinnyRx or TMates charge a membership fee?
SkinnyRx: none. TMates: none. Read from each program's own site; the prices on this page already include any fee.
Can I pay month to month at SkinnyRx and TMates?
SkinnyRx publishes a month-to-month price from $199. TMates publishes a month-to-month price from $249.
Do SkinnyRx and TMates take insurance?
SkinnyRx is cash only; TMates accepts insurance. Every price here is the cash price.
Which states do SkinnyRx and TMates serve?
SkinnyRx: 48 states. TMates: 45 states.
Do SkinnyRx or TMates sell tirzepatide or a pill?
SkinnyRx sells semaglutide injection, compounded; semaglutide, oral, compounded; tirzepatide injection, compounded; tirzepatide, oral, compounded. TMates sells semaglutide injection, compounded; tirzepatide injection, compounded.
How are SkinnyRx and TMates rated on Trustpilot?
SkinnyRx: 4.8 of 5 from 5,340 reviews. TMates: 3.2 of 5 from 1 reviews. Under 25 reviews is too few to read much into. Ratings never change our order, which is by price.
Where these numbers come from
- SkinnyRx · read October 2026
- TMates · read October 2026
Check both prices
Prices change. Each button opens the program’s own site, where the price you see at checkout is the one that counts.