Yucca Health vs Trimi: Which GLP-1 Program Is Better? (2026)
We put Yucca Health and Trimi head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend Yucca Health
Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.2 vs 8.1). That said, Trimi may be the better fit if you are looking for self-pay patients who want a flat, predictable price as their dose increases.
Yucca Health scores 9.2/10 in our independent evaluation at $146/month, while Trimi scores 8.1/10 at $99/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | Yucca Health | Trimi |
|---|---|---|
| Monthly Price | $146 | $99 |
| Rating | 9.2 / 10 | 8.1 / 10 |
| Medication Type | Compounded Only | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Free | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | No | Yes |
| Medical Support | U.S.-licensed doctors (Dr. Wasef, Dr. Sakla) guiding your care with reviews inside 24 hours | US-licensed clinicians via Arora Health |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
Yucca Health: Detailed Look
Yucca Health
A LegitScript-verified GLP-1 service with doctors you can name and pay-over-time options
Pros
- Both the pharmacy and telehealth side carry LegitScript verification
- More than 1,000 verified patient reviews put it at 4.6 out of 5 on Trustpilot
- You'll know your doctors by name: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
- Spread the cost over time through Klarna, Affirm, or Afterpay
Cons
- Locking in the lowest price means signing on for six months
- Everything's compounded here — no brand-name versions offered
People wanting a LegitScript-verified provider with real patient reviews and pay-over-time options
Trimi: Detailed Look
Trimi
Flat-price compounded GLP-1 — your cost stays the same as your dose climbs
Pros
- Flat monthly price that doesn't change as your dose is adjusted
- Compounded semaglutide from $99/mo, tirzepatide from $125/mo
- US-licensed clinicians (via Arora Health) prescribing in all 50 states
- 100% online with medication shipped to your door
Cons
- The lowest $99/$125 pricing requires an annual plan
- Compounded medications are not FDA-approved
Self-pay patients who want a flat, predictable price as their dose increases
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with Trimi at $99/month. Compounded semaglutide $99/mo and tirzepatide $125/mo on annual plans — and the price doesn't rise as your dose increases..
Yucca Health has the edge with a 9.2 rating.
Compare their support: Yucca Health offers u.s.-licensed doctors (dr. wasef, dr. sakla) guiding your care with reviews inside 24 hours, while Trimi provides us-licensed clinicians via arora health.
Yucca Health at $146/month may offer features that justify the premium.
Frequently Asked Questions
Is Yucca Health better than Trimi?
Yucca Health has a 9.2 rating while Trimi has a 8.1 rating. The better choice depends on your priorities — Yucca Health is best for people wanting a legitscript-verified provider with real patient reviews and pay-over-time options, while Trimi is best for self-pay patients who want a flat, predictable price as their dose increases.
How much does Yucca Health cost compared to Trimi?
Yucca Health starts at $146/month (six-month semaglutide plan at $146/mo, tirzepatide $258/mo. pay via klarna, affirm, or afterpay.), while Trimi starts at $99/month (compounded semaglutide $99/mo and tirzepatide $125/mo on annual plans — and the price doesn't rise as your dose increases.).
Do Yucca Health and Trimi accept insurance?
Yucca Health does not accept insurance. Trimi does not accept insurance.
Which GLP-1 medications does Yucca Health offer vs Trimi?
Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+. Trimi offers Compounded Semaglutide, Compounded Tirzepatide.
Can I cancel Yucca Health or Trimi at any time?
Yucca Health may have cancellation restrictions. Trimi also allows cancel anytime.
Are Yucca Health and Trimi available in my state?
Yucca Health is available in all 50 states. Trimi is available in all 50 states.
Not sure Yucca Health or Trimi is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.