Yucca Health vs MangoRx: Which GLP-1 Program Is Better? (2026)

We put Yucca Health and MangoRx head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend Yucca Health

Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.2 vs 7.5), more affordable pricing, availability in all 50 states. That said, MangoRx may be the better fit if you are looking for people who want one telehealth account that spans weight loss and men's health.

Yucca Health scores 9.2/10 in our independent evaluation at $146/month, while MangoRx scores 7.5/10 at $195/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
Yucca Health
$146
MangoRx
$195
Rating
Yucca Health
9.2 / 10
MangoRx
7.5 / 10
Medication Type
Yucca Health
Compounded Only
MangoRx
Compounded Only
Insurance Accepted
Yucca Health
No
MangoRx
No
States Available
Yucca Health
All 50 states
MangoRx
45 states
Consultation Fee
Yucca Health
Free
MangoRx
Free
Shipping
Yucca Health
Free Shipping
MangoRx
Free Shipping
Cancel Anytime
Yucca Health
No
MangoRx
Yes
Medical Support
Yucca Health
U.S.-licensed doctors (Dr. Wasef, Dr. Sakla) guiding your care with reviews inside 24 hours
MangoRx
Licensed U.S. physicians who stay available for continued support

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

Yucca Health: Detailed Look

Yucca Health

A LegitScript-verified GLP-1 service with doctors you can name and pay-over-time options

9.2/10
Excellent

Pros

  • Both the pharmacy and telehealth side carry LegitScript verification
  • More than 1,000 verified patient reviews put it at 4.6 out of 5 on Trustpilot
  • You'll know your doctors by name: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
  • Spread the cost over time through Klarna, Affirm, or Afterpay

Cons

  • Locking in the lowest price means signing on for six months
  • Everything's compounded here — no brand-name versions offered
Best For

People wanting a LegitScript-verified provider with real patient reviews and pay-over-time options

MangoRx: Detailed Look

MangoRx

A single telehealth service spanning weight loss, men's health, and broader wellness needs

7.5/10
Good

Pros

  • Handles more than weight loss — ED, hair loss, and skincare too
  • Every prescription is written by a licensed U.S. physician
  • Shipping is free on whatever you order
  • An easy online intake that skips the need for an appointment

Cons

  • You won't see the full pricing until you finish the intake form
  • Stocks compounded formulas only, with no brand-name versions
Best For

People who want one telehealth account that spans weight loss and men's health

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with Yucca Health at $146/month. Six-month semaglutide plan at $146/mo, tirzepatide $258/mo. Pay via Klarna, Affirm, or Afterpay..

You want the highest-rated program

Yucca Health has the edge with a 9.2 rating.

You want comprehensive medical support

Compare their support: Yucca Health offers u.s.-licensed doctors (dr. wasef, dr. sakla) guiding your care with reviews inside 24 hours, while MangoRx provides licensed u.s. physicians who stay available for continued support.

You are willing to invest more for premium care

MangoRx at $195/month may offer features that justify the premium.

Yucca Health

Starting at $146/mo · Excellent

Visit Yucca Health

MangoRx

Starting at $195/mo · Good

Visit MangoRx

Frequently Asked Questions

Is Yucca Health better than MangoRx?

Yucca Health has a 9.2 rating while MangoRx has a 7.5 rating. The better choice depends on your priorities — Yucca Health is best for people wanting a legitscript-verified provider with real patient reviews and pay-over-time options, while MangoRx is best for people who want one telehealth account that spans weight loss and men's health.

How much does Yucca Health cost compared to MangoRx?

Yucca Health starts at $146/month (six-month semaglutide plan at $146/mo, tirzepatide $258/mo. pay via klarna, affirm, or afterpay.), while MangoRx starts at $195/month (a ballpark opening figure for the glp-1 program).

Do Yucca Health and MangoRx accept insurance?

Yucca Health does not accept insurance. MangoRx does not accept insurance.

Which GLP-1 medications does Yucca Health offer vs MangoRx?

Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+. MangoRx offers Compounded Semaglutide, Compounded Tirzepatide.

Can I cancel Yucca Health or MangoRx at any time?

Yucca Health may have cancellation restrictions. MangoRx also allows cancel anytime.

Are Yucca Health and MangoRx available in my state?

Yucca Health is available in all 50 states. MangoRx is available in 45 states.

Not sure Yucca Health or MangoRx is right for you?

Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.

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