Yucca Health vs AgelessRx: Which GLP-1 Program Is Better? (2026)

We put Yucca Health and AgelessRx head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend Yucca Health

Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.2 vs 6.1). That said, AgelessRx may be the better fit if you are looking for anti-aging enthusiasts who want their glp-1 sitting next to longevity treatments.

Yucca Health scores 9.2/10 in our independent evaluation at $146/month, while AgelessRx scores 6.1/10 at $139/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
Yucca Health
$146
AgelessRx
$139
Rating
Yucca Health
9.2 / 10
AgelessRx
6.1 / 10
Medication Type
Yucca Health
Compounded Only
AgelessRx
Brand & Compounded
Insurance Accepted
Yucca Health
No
AgelessRx
No
States Available
Yucca Health
All 50 states
AgelessRx
All 50 states
Consultation Fee
Yucca Health
Free
AgelessRx
Free
Shipping
Yucca Health
Free Shipping
AgelessRx
Free Shipping
Cancel Anytime
Yucca Health
No
AgelessRx
Yes
Medical Support
Yucca Health
U.S.-licensed doctors (Dr. Wasef, Dr. Sakla) guiding your care with reviews inside 24 hours
AgelessRx
Licensed providers who stay with you for continued clinical support

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

Yucca Health: Detailed Look

Yucca Health

A LegitScript-verified GLP-1 service with doctors you can name and pay-over-time options

9.2/10
Excellent

Pros

  • Both the pharmacy and telehealth side carry LegitScript verification
  • More than 1,000 verified patient reviews put it at 4.6 out of 5 on Trustpilot
  • You'll know your doctors by name: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
  • Spread the cost over time through Klarna, Affirm, or Afterpay

Cons

  • Locking in the lowest price means signing on for six months
  • Everything's compounded here — no brand-name versions offered
Best For

People wanting a LegitScript-verified provider with real patient reviews and pay-over-time options

AgelessRx: Detailed Look

AgelessRx

An anti-aging telehealth clinic that carries compounded GLP-1s and a needle-free oral drop

6.1/10
Fair

Pros

  • A longevity-minded clinic that also stocks NAD+, rapamycin, and metformin
  • Oral GLP-1 drops on hand for anyone wanting to skip the needle
  • Consults cost nothing, with no extra provider charge layered on
  • Reaches all 50 states and lets you pay with HSA or FSA funds

Cons

  • The cold-chain injectables can be hard to get to Alaska and Hawaii
  • Its compounded formulas haven't been through an FDA safety review
Best For

Anti-aging enthusiasts who want their GLP-1 sitting next to longevity treatments

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with AgelessRx at $139/month. Semaglutide lands at $139/mo, tirzepatide at $249/mo, and liraglutide at $149/mo.

You want the highest-rated program

Yucca Health has the edge with a 9.2 rating.

You want affordable compounded options

Yucca Health focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: Yucca Health offers u.s.-licensed doctors (dr. wasef, dr. sakla) guiding your care with reviews inside 24 hours, while AgelessRx provides licensed providers who stay with you for continued clinical support.

You are willing to invest more for premium care

Yucca Health at $146/month may offer features that justify the premium.

Yucca Health

Starting at $146/mo · Excellent

Visit Yucca Health

AgelessRx

Starting at $139/mo · Fair

Visit AgelessRx

Frequently Asked Questions

Is Yucca Health better than AgelessRx?

Yucca Health has a 9.2 rating while AgelessRx has a 6.1 rating. The better choice depends on your priorities — Yucca Health is best for people wanting a legitscript-verified provider with real patient reviews and pay-over-time options, while AgelessRx is best for anti-aging enthusiasts who want their glp-1 sitting next to longevity treatments.

How much does Yucca Health cost compared to AgelessRx?

Yucca Health starts at $146/month (six-month semaglutide plan at $146/mo, tirzepatide $258/mo. pay via klarna, affirm, or afterpay.), while AgelessRx starts at $139/month (semaglutide lands at $139/mo, tirzepatide at $249/mo, and liraglutide at $149/mo).

Do Yucca Health and AgelessRx accept insurance?

Yucca Health does not accept insurance. AgelessRx does not accept insurance.

Which GLP-1 medications does Yucca Health offer vs AgelessRx?

Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+. AgelessRx offers Compounded Semaglutide, Compounded Tirzepatide, Compounded Liraglutide, Oral GLP-1 Drops, Wegovy, Zepbound.

Can I cancel Yucca Health or AgelessRx at any time?

Yucca Health may have cancellation restrictions. AgelessRx also allows cancel anytime.

Are Yucca Health and AgelessRx available in my state?

Yucca Health is available in all 50 states. AgelessRx is available in all 50 states.

Not sure Yucca Health or AgelessRx is right for you?

Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.

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