Willow vs Enhance MD: Which GLP-1 Program Is Better? (2026)

We put Willow and Enhance MD head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend Enhance MD

Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 6.9). That said, Willow may be the better fit if you are looking for shoppers seeking a middle ground between strong care and a fair price.

Enhance MD scores 8.3/10 in our independent evaluation at $249/month, while Willow scores 6.9/10 at $160/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
Willow
$160
Enhance MD
$249
Rating
Willow
6.9 / 10
Enhance MD
8.3 / 10
Medication Type
Willow
Brand & Compounded
Enhance MD
Brand & Compounded
Insurance Accepted
Willow
No
Enhance MD
No
States Available
Willow
All 50 states
Enhance MD
All 50 states
Consultation Fee
Willow
Free
Enhance MD
Included
Shipping
Willow
Free Shipping
Enhance MD
Free Shipping
Cancel Anytime
Willow
Yes
Enhance MD
Yes
Medical Support
Willow
Licensed doctors with recurring progress check-ins
Enhance MD
Board-certified doctors

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

Willow: Detailed Look

Willow

Tailored GLP-1 weight-loss treatment backed by continuous clinician follow-up

6.9/10
Fair

Pros

  • Treatment built around your individual health background
  • Care delivered by licensed doctors covering every U.S. state
  • Choice between FDA-approved brand drugs and compounded formulas
  • No shipping charges and freedom to stop whenever you like

Cons

  • Entry price runs above certain compounded-only competitors
  • Recent arrival, so seasoned patient feedback is still thin
Best For

Shoppers seeking a middle ground between strong care and a fair price

Enhance MD: Detailed Look

Enhance MD

Doctor-directed weight management that also offers NAD+ add-ons

8.3/10
Good

Pros

  • Wallet-friendly way in, with pricing that begins at $115/month
  • An uncommon NAD+ therapy choice to pair with your GLP-1
  • Every protocol is overseen by board-certified doctors

Cons

  • Claims that NAD+ aids weight loss aren't well supported by trials
  • It's hazy about which drugs are compounded versus brand-name
Best For

Cost-minded patients curious about stacking combination therapies

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with Willow at $160/month. Entry-level rate; total depends on the drug you're prescribed.

You want the highest-rated program

Enhance MD has the edge with a 8.3 rating.

You want comprehensive medical support

Compare their support: Willow offers licensed doctors with recurring progress check-ins, while Enhance MD provides board-certified doctors.

You are willing to invest more for premium care

Enhance MD at $249/month may offer features that justify the premium.

Willow

Starting at $160/mo · Fair

Visit Willow

Enhance MD

Starting at $249/mo · Good

Visit Enhance MD

Frequently Asked Questions

Is Willow better than Enhance MD?

Willow has a 6.9 rating while Enhance MD has a 8.3 rating. The better choice depends on your priorities — Willow is best for shoppers seeking a middle ground between strong care and a fair price, while Enhance MD is best for cost-minded patients curious about stacking combination therapies.

How much does Willow cost compared to Enhance MD?

Willow starts at $160/month (entry-level rate; total depends on the drug you're prescribed), while Enhance MD starts at $249/month (semaglutide runs $249/mo and tirzepatide $379/mo, with yearly plans trimming roughly 15%).

Do Willow and Enhance MD accept insurance?

Willow does not accept insurance. Enhance MD does not accept insurance.

Which GLP-1 medications does Willow offer vs Enhance MD?

Willow offers Semaglutide, Tirzepatide. Enhance MD offers Semaglutide, Tirzepatide, NAD+.

Can I cancel Willow or Enhance MD at any time?

Willow allows cancel anytime. Enhance MD also allows cancel anytime.

Are Willow and Enhance MD available in my state?

Willow is available in all 50 states. Enhance MD is available in all 50 states.

Not sure Willow or Enhance MD is right for you?

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