TrimRx vs Yucca Health: Which GLP-1 Program Is Better? (2026)

We put TrimRx and Yucca Health head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend TrimRx

Between these two providers, TrimRx is our pick for most users. It offers a higher overall rating (9.3 vs 9.2). That said, Yucca Health may be the better fit if you are looking for people wanting a legitscript-verified provider with real patient reviews and pay-over-time options.

TrimRx scores 9.3/10 in our independent evaluation at $179/month, while Yucca Health scores 9.2/10 at $146/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
TrimRx
$179
Yucca Health
$146
Rating
TrimRx
9.3 / 10
Yucca Health
9.2 / 10
Medication Type
TrimRx
Compounded Only
Yucca Health
Compounded Only
Insurance Accepted
TrimRx
No
Yucca Health
No
States Available
TrimRx
45 states
Yucca Health
All 50 states
Consultation Fee
TrimRx
Free
Yucca Health
Free
Shipping
TrimRx
Free Shipping
Yucca Health
Free Shipping
Cancel Anytime
TrimRx
Yes
Yucca Health
No
Medical Support
TrimRx
Licensed doctors, individualized consultations, and unlimited check-ins
Yucca Health
U.S.-licensed doctors (Dr. Wasef, Dr. Sakla) guiding your care with reviews inside 24 hours

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

TrimRx: Detailed Look

TrimRx

One-on-one GLP-1 consultations, prescriptions matched to you, and steady doctor support

9.3/10
Excellent

Pros

  • Doctor consultations shaped around your personal health history
  • One bundled price with no buried fees or unexpected bills
  • Free shipping and as many medical check-ins as you need
  • Contract-free, so you can pause or stop treatment whenever

Cons

  • Dispenses compounded formulas only, with no brand drugs
  • Offered in a limited set of states rather than all 50
Best For

Anyone seeking individualized doctor consultations with clear, all-in pricing

Yucca Health: Detailed Look

Yucca Health

A LegitScript-verified GLP-1 service with doctors you can name and pay-over-time options

9.2/10
Excellent

Pros

  • Both the pharmacy and telehealth side carry LegitScript verification
  • More than 1,000 verified patient reviews put it at 4.6 out of 5 on Trustpilot
  • You'll know your doctors by name: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
  • Spread the cost over time through Klarna, Affirm, or Afterpay

Cons

  • Locking in the lowest price means signing on for six months
  • Everything's compounded here — no brand-name versions offered
Best For

People wanting a LegitScript-verified provider with real patient reviews and pay-over-time options

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with Yucca Health at $146/month. Six-month semaglutide plan at $146/mo, tirzepatide $258/mo. Pay via Klarna, Affirm, or Afterpay..

You want the highest-rated program

TrimRx has the edge with a 9.3 rating.

You want comprehensive medical support

Compare their support: TrimRx offers licensed doctors, individualized consultations, and unlimited check-ins, while Yucca Health provides u.s.-licensed doctors (dr. wasef, dr. sakla) guiding your care with reviews inside 24 hours.

You are willing to invest more for premium care

TrimRx at $179/month may offer features that justify the premium.

TrimRx

Starting at $179/mo · Excellent

Visit TrimRx

Yucca Health

Starting at $146/mo · Excellent

Visit Yucca Health

Frequently Asked Questions

Is TrimRx better than Yucca Health?

TrimRx has a 9.3 rating while Yucca Health has a 9.2 rating. The better choice depends on your priorities — TrimRx is best for anyone seeking individualized doctor consultations with clear, all-in pricing, while Yucca Health is best for people wanting a legitscript-verified provider with real patient reviews and pay-over-time options.

How much does TrimRx cost compared to Yucca Health?

TrimRx starts at $179/month (semaglutide starts at $199/mo and tirzepatide at $299/mo, all bundled into one price.), while Yucca Health starts at $146/month (six-month semaglutide plan at $146/mo, tirzepatide $258/mo. pay via klarna, affirm, or afterpay.).

Do TrimRx and Yucca Health accept insurance?

TrimRx does not accept insurance. Yucca Health does not accept insurance.

Which GLP-1 medications does TrimRx offer vs Yucca Health?

TrimRx offers Compounded Semaglutide, Compounded Tirzepatide. Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+.

Can I cancel TrimRx or Yucca Health at any time?

TrimRx allows cancel anytime. Yucca Health may have cancellation restrictions.

Are TrimRx and Yucca Health available in my state?

TrimRx is available in 45 states. Yucca Health is available in all 50 states.

Not sure TrimRx or Yucca Health is right for you?

Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.

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