TrimRx vs Sesame Care: Which GLP-1 Program Is Better? (2026)
We put TrimRx and Sesame Care head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend TrimRx
Between these two providers, TrimRx is our pick for most users. It offers a higher overall rating (9.3 vs 7.2), more affordable pricing. That said, Sesame Care may be the better fit if you are looking for insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately.
TrimRx scores 9.3/10 in our independent evaluation at $179/month, while Sesame Care scores 7.2/10 at $225/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | TrimRx | Sesame Care |
|---|---|---|
| Monthly Price | $179 | $225 |
| Rating | 9.3 / 10 | 7.2 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | No | Yes |
| States Available | 45 states | All 50 states |
| Consultation Fee | Free | $25-75 |
| Shipping | Free Shipping | Paid |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed doctors, individualized consultations, and unlimited check-ins | Licensed physicians booked one visit at a time |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
TrimRx: Detailed Look
TrimRx
One-on-one GLP-1 consultations, prescriptions matched to you, and steady doctor support
Pros
- Doctor consultations shaped around your personal health history
- One bundled price with no buried fees or unexpected bills
- Free shipping and as many medical check-ins as you need
- Contract-free, so you can pause or stop treatment whenever
Cons
- Dispenses compounded formulas only, with no brand drugs
- Offered in a limited set of states rather than all 50
Anyone seeking individualized doctor consultations with clear, all-in pricing
Sesame Care: Detailed Look
Sesame Care
A low-cost telehealth marketplace that matches you with a doctor for as little as $25
Pros
- About the cheapest consult you'll find, with visits opening at $25
- Writes scripts for FDA-approved brand-name drugs
- Clear pay-per-visit pricing and nothing to subscribe to
- A broad bench of licensed physicians spanning all 50 states
Cons
- What the drug costs is billed on its own, apart from the visit fee
- No compounded route here — it's brand-name only, so the drug runs pricier
Insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with TrimRx at $179/month. Semaglutide starts at $199/mo and tirzepatide at $299/mo, all bundled into one price..
TrimRx has the edge with a 9.3 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
TrimRx focuses on compounded medications at a lower price point.
Compare their support: TrimRx offers licensed doctors, individualized consultations, and unlimited check-ins, while Sesame Care provides licensed physicians booked one visit at a time.
Sesame Care at $225/month may offer features that justify the premium.
Frequently Asked Questions
Is TrimRx better than Sesame Care?
TrimRx has a 9.3 rating while Sesame Care has a 7.2 rating. The better choice depends on your priorities — TrimRx is best for anyone seeking individualized doctor consultations with clear, all-in pricing, while Sesame Care is best for insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately.
How much does TrimRx cost compared to Sesame Care?
TrimRx starts at $179/month (semaglutide starts at $199/mo and tirzepatide at $299/mo, all bundled into one price.), while Sesame Care starts at $225/month (visits run $25-75, and the medication is billed separately at pharmacy rates ($200-1,400/mo). with insurance savings cards the total opens around $225/mo. the drug is not part of the visit fee.).
Do TrimRx and Sesame Care accept insurance?
TrimRx does not accept insurance. Sesame Care accepts insurance.
Which GLP-1 medications does TrimRx offer vs Sesame Care?
TrimRx offers Compounded Semaglutide, Compounded Tirzepatide. Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus.
Can I cancel TrimRx or Sesame Care at any time?
TrimRx allows cancel anytime. Sesame Care also allows cancel anytime.
Are TrimRx and Sesame Care available in my state?
TrimRx is available in 45 states. Sesame Care is available in all 50 states.
Not sure TrimRx or Sesame Care is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.