TMates vs Trimi: Which GLP-1 Program Is Better? (2026)

We put TMates and Trimi head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend Trimi

Between these two providers, Trimi is our pick for most users. It offers a higher overall rating (8.1 vs 7.8), more affordable pricing, availability in all 50 states. That said, TMates may be the better fit if you are looking for insured patients who want a coached glp-1 program with a few medication choices.

Trimi scores 8.1/10 in our independent evaluation at $99/month, while TMates scores 7.8/10 at $199/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
TMates
$199
Trimi
$99
Rating
TMates
7.8 / 10
Trimi
8.1 / 10
Medication Type
TMates
Compounded Only
Trimi
Compounded Only
Insurance Accepted
TMates
Yes
Trimi
No
States Available
TMates
45 states
Trimi
All 50 states
Consultation Fee
TMates
Included
Trimi
Free
Shipping
TMates
Free Shipping
Trimi
Free Shipping
Cancel Anytime
TMates
Yes
Trimi
Yes
Medical Support
TMates
Licensed clinicians paired with text-message coaching and digital check-ins
Trimi
US-licensed clinicians via Arora Health

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

TMates: Detailed Look

TMates

A GLP-1 weight loss program you can put through most major insurance plans

7.8/10
Good

Pros

  • Among the rare GLP-1 services that will actually take major insurance
  • A single flat rate wraps in meds, visits, coaching, and delivery
  • Text-based coaching and digital check-ins run around the clock
  • Phentermine is available for those who aren't GLP-1 candidates

Cons

  • It's a younger platform, so independent reviews remain sparse
  • You'll need to enroll before the full program details are confirmed
Best For

Insured patients who want a coached GLP-1 program with a few medication choices

Trimi: Detailed Look

Trimi

Flat-price compounded GLP-1 — your cost stays the same as your dose climbs

8.1/10
Very Good

Pros

  • Flat monthly price that doesn't change as your dose is adjusted
  • Compounded semaglutide from $99/mo, tirzepatide from $125/mo
  • US-licensed clinicians (via Arora Health) prescribing in all 50 states
  • 100% online with medication shipped to your door

Cons

  • The lowest $99/$125 pricing requires an annual plan
  • Compounded medications are not FDA-approved
Best For

Self-pay patients who want a flat, predictable price as their dose increases

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with Trimi at $99/month. Compounded semaglutide $99/mo and tirzepatide $125/mo on annual plans — and the price doesn't rise as your dose increases..

You want the highest-rated program

Trimi has the edge with a 8.1 rating.

You have insurance coverage

TMates accepts insurance, which can significantly reduce your out-of-pocket cost.

You want comprehensive medical support

Compare their support: TMates offers licensed clinicians paired with text-message coaching and digital check-ins, while Trimi provides us-licensed clinicians via arora health.

You are willing to invest more for premium care

TMates at $199/month may offer features that justify the premium.

TMates

Starting at $199/mo · Good

Visit TMates

Trimi

Starting at $99/mo · Very Good

Visit Trimi

Frequently Asked Questions

Is TMates better than Trimi?

TMates has a 7.8 rating while Trimi has a 8.1 rating. The better choice depends on your priorities — TMates is best for insured patients who want a coached glp-1 program with a few medication choices, while Trimi is best for self-pay patients who want a flat, predictable price as their dose increases.

How much does TMates cost compared to Trimi?

TMates starts at $199/month (semaglutide at $199/mo, tirzepatide at $297/mo), while Trimi starts at $99/month (compounded semaglutide $99/mo and tirzepatide $125/mo on annual plans — and the price doesn't rise as your dose increases.).

Do TMates and Trimi accept insurance?

TMates accepts insurance. Trimi does not accept insurance.

Which GLP-1 medications does TMates offer vs Trimi?

TMates offers Compounded Semaglutide, Compounded Tirzepatide, Phentermine. Trimi offers Compounded Semaglutide, Compounded Tirzepatide.

Can I cancel TMates or Trimi at any time?

TMates allows cancel anytime. Trimi also allows cancel anytime.

Are TMates and Trimi available in my state?

TMates is available in 45 states. Trimi is available in all 50 states.

Not sure TMates or Trimi is right for you?

Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.

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