SkinnyRx vs Yucca Health: Which GLP-1 Program Is Better? (2026)
We put SkinnyRx and Yucca Health head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend Yucca Health
Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.2 vs 9.1), more affordable pricing, availability in all 50 states. That said, SkinnyRx may be the better fit if you are looking for people who want their glp-1 in several formats — tablet, sublingual, or injection.
Yucca Health scores 9.2/10 in our independent evaluation at $146/month, while SkinnyRx scores 9.1/10 at $199/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | SkinnyRx | Yucca Health |
|---|---|---|
| Monthly Price | $199 | $146 |
| Rating | 9.1 / 10 | 9.2 / 10 |
| Medication Type | Compounded Only | Compounded Only |
| Insurance Accepted | No | No |
| States Available | 48 states | All 50 states |
| Consultation Fee | Included | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | No |
| Medical Support | U.S.-licensed doctors who turn around prescription reviews in 24-48 hours | U.S.-licensed doctors (Dr. Wasef, Dr. Sakla) guiding your care with reviews inside 24 hours |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
SkinnyRx: Detailed Look
SkinnyRx
A rapidly scaling GLP-1 service offering pills, sublinguals, and shots with Affirm financing
Pros
- Take it three ways — as a shot, under the tongue, or as a tablet
- Overnight delivery is free and ships from FDA-regulated U.S. pharmacies
- Billed month to month, so you're never locked into a contract
- Thousands of verified Trustpilot reviews average a 4.8 out of 5
Cons
- You'll pay cash — they don't run anything through insurance
- Only compounded formulas here; brand-name versions aren't offered
People who want their GLP-1 in several formats — tablet, sublingual, or injection
Yucca Health: Detailed Look
Yucca Health
A LegitScript-verified GLP-1 service with doctors you can name and pay-over-time options
Pros
- Both the pharmacy and telehealth side carry LegitScript verification
- More than 1,000 verified patient reviews put it at 4.6 out of 5 on Trustpilot
- You'll know your doctors by name: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
- Spread the cost over time through Klarna, Affirm, or Afterpay
Cons
- Locking in the lowest price means signing on for six months
- Everything's compounded here — no brand-name versions offered
People wanting a LegitScript-verified provider with real patient reviews and pay-over-time options
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with Yucca Health at $146/month. Six-month semaglutide plan at $146/mo, tirzepatide $258/mo. Pay via Klarna, Affirm, or Afterpay..
Yucca Health has the edge with a 9.2 rating.
Compare their support: SkinnyRx offers u.s.-licensed doctors who turn around prescription reviews in 24-48 hours, while Yucca Health provides u.s.-licensed doctors (dr. wasef, dr. sakla) guiding your care with reviews inside 24 hours.
SkinnyRx at $199/month may offer features that justify the premium.
Frequently Asked Questions
Is SkinnyRx better than Yucca Health?
SkinnyRx has a 9.1 rating while Yucca Health has a 9.2 rating. The better choice depends on your priorities — SkinnyRx is best for people who want their glp-1 in several formats — tablet, sublingual, or injection, while Yucca Health is best for people wanting a legitscript-verified provider with real patient reviews and pay-over-time options.
How much does SkinnyRx cost compared to Yucca Health?
SkinnyRx starts at $199/month (semaglutide runs $199/mo; tirzepatide climbs as high as $349/mo), while Yucca Health starts at $146/month (six-month semaglutide plan at $146/mo, tirzepatide $258/mo. pay via klarna, affirm, or afterpay.).
Do SkinnyRx and Yucca Health accept insurance?
SkinnyRx does not accept insurance. Yucca Health does not accept insurance.
Which GLP-1 medications does SkinnyRx offer vs Yucca Health?
SkinnyRx offers Compounded Semaglutide (Injectable), Compounded Semaglutide (Sublingual), Compounded Tirzepatide (Injectable), Compounded Tirzepatide (Tablets). Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+.
Can I cancel SkinnyRx or Yucca Health at any time?
SkinnyRx allows cancel anytime. Yucca Health may have cancellation restrictions.
Are SkinnyRx and Yucca Health available in my state?
SkinnyRx is available in 48 states. Yucca Health is available in all 50 states.
Not sure SkinnyRx or Yucca Health is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.