SkinnyRx vs Trimi: Which GLP-1 Program Is Better? (2026)

We put SkinnyRx and Trimi head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend SkinnyRx

Between these two providers, SkinnyRx is our pick for most users. It offers a higher overall rating (9.1 vs 8.1). That said, Trimi may be the better fit if you are looking for self-pay patients who want a flat, predictable price as their dose increases.

SkinnyRx scores 9.1/10 in our independent evaluation at $199/month, while Trimi scores 8.1/10 at $99/month. Both programs connect you with a licensed physician and deliver medication straight to your door. SkinnyRx also offers oral GLP-1 options for patients who prefer pills over injections. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
SkinnyRx
$199
Trimi
$99
Rating
SkinnyRx
9.1 / 10
Trimi
8.1 / 10
Medication Type
SkinnyRx
Compounded Only
Trimi
Compounded Only
Insurance Accepted
SkinnyRx
No
Trimi
No
States Available
SkinnyRx
48 states
Trimi
All 50 states
Consultation Fee
SkinnyRx
Included
Trimi
Free
Shipping
SkinnyRx
Free Shipping
Trimi
Free Shipping
Cancel Anytime
SkinnyRx
Yes
Trimi
Yes
Medical Support
SkinnyRx
U.S.-licensed doctors who turn around prescription reviews in 24-48 hours
Trimi
US-licensed clinicians via Arora Health

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

SkinnyRx: Detailed Look

SkinnyRx

A rapidly scaling GLP-1 service offering pills, sublinguals, and shots with Affirm financing

9.1/10
Excellent

Pros

  • Take it three ways — as a shot, under the tongue, or as a tablet
  • Overnight delivery is free and ships from FDA-regulated U.S. pharmacies
  • Billed month to month, so you're never locked into a contract
  • Thousands of verified Trustpilot reviews average a 4.8 out of 5

Cons

  • You'll pay cash — they don't run anything through insurance
  • Only compounded formulas here; brand-name versions aren't offered
Best For

People who want their GLP-1 in several formats — tablet, sublingual, or injection

Trimi: Detailed Look

Trimi

Flat-price compounded GLP-1 — your cost stays the same as your dose climbs

8.1/10
Very Good

Pros

  • Flat monthly price that doesn't change as your dose is adjusted
  • Compounded semaglutide from $99/mo, tirzepatide from $125/mo
  • US-licensed clinicians (via Arora Health) prescribing in all 50 states
  • 100% online with medication shipped to your door

Cons

  • The lowest $99/$125 pricing requires an annual plan
  • Compounded medications are not FDA-approved
Best For

Self-pay patients who want a flat, predictable price as their dose increases

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with Trimi at $99/month. Compounded semaglutide $99/mo and tirzepatide $125/mo on annual plans — and the price doesn't rise as your dose increases..

You want the highest-rated program

SkinnyRx has the edge with a 9.1 rating.

You want comprehensive medical support

Compare their support: SkinnyRx offers u.s.-licensed doctors who turn around prescription reviews in 24-48 hours, while Trimi provides us-licensed clinicians via arora health.

You are willing to invest more for premium care

SkinnyRx at $199/month may offer features that justify the premium.

SkinnyRx

Starting at $199/mo · Excellent

Visit SkinnyRx

Trimi

Starting at $99/mo · Very Good

Visit Trimi

Frequently Asked Questions

Is SkinnyRx better than Trimi?

SkinnyRx has a 9.1 rating while Trimi has a 8.1 rating. The better choice depends on your priorities — SkinnyRx is best for people who want their glp-1 in several formats — tablet, sublingual, or injection, while Trimi is best for self-pay patients who want a flat, predictable price as their dose increases.

How much does SkinnyRx cost compared to Trimi?

SkinnyRx starts at $199/month (semaglutide runs $199/mo; tirzepatide climbs as high as $349/mo), while Trimi starts at $99/month (compounded semaglutide $99/mo and tirzepatide $125/mo on annual plans — and the price doesn't rise as your dose increases.).

Do SkinnyRx and Trimi accept insurance?

SkinnyRx does not accept insurance. Trimi does not accept insurance.

Which GLP-1 medications does SkinnyRx offer vs Trimi?

SkinnyRx offers Compounded Semaglutide (Injectable), Compounded Semaglutide (Sublingual), Compounded Tirzepatide (Injectable), Compounded Tirzepatide (Tablets). Trimi offers Compounded Semaglutide, Compounded Tirzepatide.

Can I cancel SkinnyRx or Trimi at any time?

SkinnyRx allows cancel anytime. Trimi also allows cancel anytime.

Are SkinnyRx and Trimi available in my state?

SkinnyRx is available in 48 states. Trimi is available in all 50 states.

Not sure SkinnyRx or Trimi is right for you?

Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.

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