SkinnyRx vs Sesame Care: Which GLP-1 Program Is Better? (2026)
We put SkinnyRx and Sesame Care head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend SkinnyRx
Between these two providers, SkinnyRx is our pick for most users. It offers a higher overall rating (9.1 vs 7.2), more affordable pricing. That said, Sesame Care may be the better fit if you are looking for insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately.
SkinnyRx scores 9.1/10 in our independent evaluation at $199/month, while Sesame Care scores 7.2/10 at $225/month. Both programs connect you with a licensed physician and deliver medication straight to your door. SkinnyRx also offers oral GLP-1 options for patients who prefer pills over injections. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | SkinnyRx | Sesame Care |
|---|---|---|
| Monthly Price | $199 | $225 |
| Rating | 9.1 / 10 | 7.2 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | No | Yes |
| States Available | 48 states | All 50 states |
| Consultation Fee | Included | $25-75 |
| Shipping | Free Shipping | Paid |
| Cancel Anytime | Yes | Yes |
| Medical Support | U.S.-licensed doctors who turn around prescription reviews in 24-48 hours | Licensed physicians booked one visit at a time |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
SkinnyRx: Detailed Look
SkinnyRx
A rapidly scaling GLP-1 service offering pills, sublinguals, and shots with Affirm financing
Pros
- Take it three ways — as a shot, under the tongue, or as a tablet
- Overnight delivery is free and ships from FDA-regulated U.S. pharmacies
- Billed month to month, so you're never locked into a contract
- Thousands of verified Trustpilot reviews average a 4.8 out of 5
Cons
- You'll pay cash — they don't run anything through insurance
- Only compounded formulas here; brand-name versions aren't offered
People who want their GLP-1 in several formats — tablet, sublingual, or injection
Sesame Care: Detailed Look
Sesame Care
A low-cost telehealth marketplace that matches you with a doctor for as little as $25
Pros
- About the cheapest consult you'll find, with visits opening at $25
- Writes scripts for FDA-approved brand-name drugs
- Clear pay-per-visit pricing and nothing to subscribe to
- A broad bench of licensed physicians spanning all 50 states
Cons
- What the drug costs is billed on its own, apart from the visit fee
- No compounded route here — it's brand-name only, so the drug runs pricier
Insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with SkinnyRx at $199/month. Semaglutide runs $199/mo; tirzepatide climbs as high as $349/mo.
SkinnyRx has the edge with a 9.1 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
SkinnyRx focuses on compounded medications at a lower price point.
Compare their support: SkinnyRx offers u.s.-licensed doctors who turn around prescription reviews in 24-48 hours, while Sesame Care provides licensed physicians booked one visit at a time.
Sesame Care at $225/month may offer features that justify the premium.
Frequently Asked Questions
Is SkinnyRx better than Sesame Care?
SkinnyRx has a 9.1 rating while Sesame Care has a 7.2 rating. The better choice depends on your priorities — SkinnyRx is best for people who want their glp-1 in several formats — tablet, sublingual, or injection, while Sesame Care is best for insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately.
How much does SkinnyRx cost compared to Sesame Care?
SkinnyRx starts at $199/month (semaglutide runs $199/mo; tirzepatide climbs as high as $349/mo), while Sesame Care starts at $225/month (visits run $25-75, and the medication is billed separately at pharmacy rates ($200-1,400/mo). with insurance savings cards the total opens around $225/mo. the drug is not part of the visit fee.).
Do SkinnyRx and Sesame Care accept insurance?
SkinnyRx does not accept insurance. Sesame Care accepts insurance.
Which GLP-1 medications does SkinnyRx offer vs Sesame Care?
SkinnyRx offers Compounded Semaglutide (Injectable), Compounded Semaglutide (Sublingual), Compounded Tirzepatide (Injectable), Compounded Tirzepatide (Tablets). Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus.
Can I cancel SkinnyRx or Sesame Care at any time?
SkinnyRx allows cancel anytime. Sesame Care also allows cancel anytime.
Are SkinnyRx and Sesame Care available in my state?
SkinnyRx is available in 48 states. Sesame Care is available in all 50 states.
Not sure SkinnyRx or Sesame Care is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.