ShedRx vs Yucca Health: Which GLP-1 Program Is Better? (2026)
We put ShedRx and Yucca Health head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend Yucca Health
Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.2 vs 8.8), more affordable pricing. That said, ShedRx may be the better fit if you are looking for people who want several ways to take their medication plus a money-back results promise.
Yucca Health scores 9.2/10 in our independent evaluation at $146/month, while ShedRx scores 8.8/10 at $199/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | ShedRx | Yucca Health |
|---|---|---|
| Monthly Price | $199 | $146 |
| Rating | 8.8 / 10 | 9.2 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Included | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | No |
| Medical Support | Licensed doctors alongside health coaching and supplement advice | U.S.-licensed doctors (Dr. Wasef, Dr. Sakla) guiding your care with reviews inside 24 hours |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
ShedRx: Detailed Look
ShedRx
Over 150K members and 5 ways to take it — shots, oral drops, lozenges, tablets, and pills
Pros
- More ways to take it than any rival: shots, oral drops, lozenges, tablets, and pills
- Promise of 10% weight loss inside 9 months or your money back
- Compounded formulas plus brand drugs like Wegovy and Zepbound
- Membership tops 150,000, with coaching and supplements built in
Cons
- Cost rises as your dose grows, reaching as much as $299/mo
- Support feedback is uneven, and reply times can drag
People who want several ways to take their medication plus a money-back results promise
Yucca Health: Detailed Look
Yucca Health
A LegitScript-verified GLP-1 service with doctors you can name and pay-over-time options
Pros
- Both the pharmacy and telehealth side carry LegitScript verification
- More than 1,000 verified patient reviews put it at 4.6 out of 5 on Trustpilot
- You'll know your doctors by name: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
- Spread the cost over time through Klarna, Affirm, or Afterpay
Cons
- Locking in the lowest price means signing on for six months
- Everything's compounded here — no brand-name versions offered
People wanting a LegitScript-verified provider with real patient reviews and pay-over-time options
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with Yucca Health at $146/month. Six-month semaglutide plan at $146/mo, tirzepatide $258/mo. Pay via Klarna, Affirm, or Afterpay..
Yucca Health has the edge with a 9.2 rating.
Yucca Health focuses on compounded medications at a lower price point.
Compare their support: ShedRx offers licensed doctors alongside health coaching and supplement advice, while Yucca Health provides u.s.-licensed doctors (dr. wasef, dr. sakla) guiding your care with reviews inside 24 hours.
ShedRx at $199/month may offer features that justify the premium.
Frequently Asked Questions
Is ShedRx better than Yucca Health?
ShedRx has a 8.8 rating while Yucca Health has a 9.2 rating. The better choice depends on your priorities — ShedRx is best for people who want several ways to take their medication plus a money-back results promise, while Yucca Health is best for people wanting a legitscript-verified provider with real patient reviews and pay-over-time options.
How much does ShedRx cost compared to Yucca Health?
ShedRx starts at $199/month (semaglutide opens at $199/mo and climbs toward $299/mo on larger doses. brand route runs $99/mo plus whatever the pharmacy charges.), while Yucca Health starts at $146/month (six-month semaglutide plan at $146/mo, tirzepatide $258/mo. pay via klarna, affirm, or afterpay.).
Do ShedRx and Yucca Health accept insurance?
ShedRx does not accept insurance. Yucca Health does not accept insurance.
Which GLP-1 medications does ShedRx offer vs Yucca Health?
ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound. Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+.
Can I cancel ShedRx or Yucca Health at any time?
ShedRx allows cancel anytime. Yucca Health may have cancellation restrictions.
Are ShedRx and Yucca Health available in my state?
ShedRx is available in all 50 states. Yucca Health is available in all 50 states.
Not sure ShedRx or Yucca Health is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.