ShedRx vs Trimi: Which GLP-1 Program Is Better? (2026)
We put ShedRx and Trimi head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend ShedRx
Between these two providers, ShedRx is our pick for most users. It offers a higher overall rating (8.8 vs 8.1), both brand-name and compounded medication options. That said, Trimi may be the better fit if you are looking for self-pay patients who want a flat, predictable price as their dose increases.
ShedRx scores 8.8/10 in our independent evaluation at $199/month, while Trimi scores 8.1/10 at $99/month. Both programs connect you with a licensed physician and deliver medication straight to your door. ShedRx also offers oral GLP-1 options for patients who prefer pills over injections. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | ShedRx | Trimi |
|---|---|---|
| Monthly Price | $199 | $99 |
| Rating | 8.8 / 10 | 8.1 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Included | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed doctors alongside health coaching and supplement advice | US-licensed clinicians via Arora Health |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
ShedRx: Detailed Look
ShedRx
Over 150K members and 5 ways to take it — shots, oral drops, lozenges, tablets, and pills
Pros
- More ways to take it than any rival: shots, oral drops, lozenges, tablets, and pills
- Promise of 10% weight loss inside 9 months or your money back
- Compounded formulas plus brand drugs like Wegovy and Zepbound
- Membership tops 150,000, with coaching and supplements built in
Cons
- Cost rises as your dose grows, reaching as much as $299/mo
- Support feedback is uneven, and reply times can drag
People who want several ways to take their medication plus a money-back results promise
Trimi: Detailed Look
Trimi
Flat-price compounded GLP-1 — your cost stays the same as your dose climbs
Pros
- Flat monthly price that doesn't change as your dose is adjusted
- Compounded semaglutide from $99/mo, tirzepatide from $125/mo
- US-licensed clinicians (via Arora Health) prescribing in all 50 states
- 100% online with medication shipped to your door
Cons
- The lowest $99/$125 pricing requires an annual plan
- Compounded medications are not FDA-approved
Self-pay patients who want a flat, predictable price as their dose increases
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with Trimi at $99/month. Compounded semaglutide $99/mo and tirzepatide $125/mo on annual plans — and the price doesn't rise as your dose increases..
ShedRx has the edge with a 8.8 rating.
Trimi focuses on compounded medications at a lower price point.
Compare their support: ShedRx offers licensed doctors alongside health coaching and supplement advice, while Trimi provides us-licensed clinicians via arora health.
ShedRx at $199/month may offer features that justify the premium.
Frequently Asked Questions
Is ShedRx better than Trimi?
ShedRx has a 8.8 rating while Trimi has a 8.1 rating. The better choice depends on your priorities — ShedRx is best for people who want several ways to take their medication plus a money-back results promise, while Trimi is best for self-pay patients who want a flat, predictable price as their dose increases.
How much does ShedRx cost compared to Trimi?
ShedRx starts at $199/month (semaglutide opens at $199/mo and climbs toward $299/mo on larger doses. brand route runs $99/mo plus whatever the pharmacy charges.), while Trimi starts at $99/month (compounded semaglutide $99/mo and tirzepatide $125/mo on annual plans — and the price doesn't rise as your dose increases.).
Do ShedRx and Trimi accept insurance?
ShedRx does not accept insurance. Trimi does not accept insurance.
Which GLP-1 medications does ShedRx offer vs Trimi?
ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound. Trimi offers Compounded Semaglutide, Compounded Tirzepatide.
Can I cancel ShedRx or Trimi at any time?
ShedRx allows cancel anytime. Trimi also allows cancel anytime.
Are ShedRx and Trimi available in my state?
ShedRx is available in all 50 states. Trimi is available in all 50 states.
Not sure ShedRx or Trimi is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.