ShedRx vs TrimRx: Which GLP-1 Program Is Better? (2026)

We put ShedRx and TrimRx head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend TrimRx

Between these two providers, TrimRx is our pick for most users. It offers a higher overall rating (9.3 vs 8.8), more affordable pricing. That said, ShedRx may be the better fit if you are looking for people who want several ways to take their medication plus a money-back results promise.

TrimRx scores 9.3/10 in our independent evaluation at $179/month, while ShedRx scores 8.8/10 at $199/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
ShedRx
$199
TrimRx
$179
Rating
ShedRx
8.8 / 10
TrimRx
9.3 / 10
Medication Type
ShedRx
Brand & Compounded
TrimRx
Compounded Only
Insurance Accepted
ShedRx
No
TrimRx
No
States Available
ShedRx
All 50 states
TrimRx
45 states
Consultation Fee
ShedRx
Included
TrimRx
Free
Shipping
ShedRx
Free Shipping
TrimRx
Free Shipping
Cancel Anytime
ShedRx
Yes
TrimRx
Yes
Medical Support
ShedRx
Licensed doctors alongside health coaching and supplement advice
TrimRx
Licensed doctors, individualized consultations, and unlimited check-ins

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

ShedRx: Detailed Look

ShedRx

Over 150K members and 5 ways to take it — shots, oral drops, lozenges, tablets, and pills

8.8/10
Very Good

Pros

  • More ways to take it than any rival: shots, oral drops, lozenges, tablets, and pills
  • Promise of 10% weight loss inside 9 months or your money back
  • Compounded formulas plus brand drugs like Wegovy and Zepbound
  • Membership tops 150,000, with coaching and supplements built in

Cons

  • Cost rises as your dose grows, reaching as much as $299/mo
  • Support feedback is uneven, and reply times can drag
Best For

People who want several ways to take their medication plus a money-back results promise

TrimRx: Detailed Look

TrimRx

One-on-one GLP-1 consultations, prescriptions matched to you, and steady doctor support

9.3/10
Excellent

Pros

  • Doctor consultations shaped around your personal health history
  • One bundled price with no buried fees or unexpected bills
  • Free shipping and as many medical check-ins as you need
  • Contract-free, so you can pause or stop treatment whenever

Cons

  • Dispenses compounded formulas only, with no brand drugs
  • Offered in a limited set of states rather than all 50
Best For

Anyone seeking individualized doctor consultations with clear, all-in pricing

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with TrimRx at $179/month. Semaglutide starts at $199/mo and tirzepatide at $299/mo, all bundled into one price..

You want the highest-rated program

TrimRx has the edge with a 9.3 rating.

You want affordable compounded options

TrimRx focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: ShedRx offers licensed doctors alongside health coaching and supplement advice, while TrimRx provides licensed doctors, individualized consultations, and unlimited check-ins.

You are willing to invest more for premium care

ShedRx at $199/month may offer features that justify the premium.

ShedRx

Starting at $199/mo · Very Good

Visit ShedRx

TrimRx

Starting at $179/mo · Excellent

Visit TrimRx

Frequently Asked Questions

Is ShedRx better than TrimRx?

ShedRx has a 8.8 rating while TrimRx has a 9.3 rating. The better choice depends on your priorities — ShedRx is best for people who want several ways to take their medication plus a money-back results promise, while TrimRx is best for anyone seeking individualized doctor consultations with clear, all-in pricing.

How much does ShedRx cost compared to TrimRx?

ShedRx starts at $199/month (semaglutide opens at $199/mo and climbs toward $299/mo on larger doses. brand route runs $99/mo plus whatever the pharmacy charges.), while TrimRx starts at $179/month (semaglutide starts at $199/mo and tirzepatide at $299/mo, all bundled into one price.).

Do ShedRx and TrimRx accept insurance?

ShedRx does not accept insurance. TrimRx does not accept insurance.

Which GLP-1 medications does ShedRx offer vs TrimRx?

ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound. TrimRx offers Compounded Semaglutide, Compounded Tirzepatide.

Can I cancel ShedRx or TrimRx at any time?

ShedRx allows cancel anytime. TrimRx also allows cancel anytime.

Are ShedRx and TrimRx available in my state?

ShedRx is available in all 50 states. TrimRx is available in 45 states.

Not sure ShedRx or TrimRx is right for you?

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