ShedRx vs SkinnyRx: Which GLP-1 Program Is Better? (2026)

We put ShedRx and SkinnyRx head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend SkinnyRx

Between these two providers, SkinnyRx is our pick for most users. It offers a higher overall rating (9.1 vs 8.8). That said, ShedRx may be the better fit if you are looking for people who want several ways to take their medication plus a money-back results promise.

SkinnyRx scores 9.1/10 in our independent evaluation at $199/month, while ShedRx scores 8.8/10 at $199/month. Both programs connect you with a licensed physician and deliver medication straight to your door. SkinnyRx also offers oral GLP-1 options for patients who prefer pills over injections. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
ShedRx
$199
SkinnyRx
$199
Rating
ShedRx
8.8 / 10
SkinnyRx
9.1 / 10
Medication Type
ShedRx
Brand & Compounded
SkinnyRx
Compounded Only
Insurance Accepted
ShedRx
No
SkinnyRx
No
States Available
ShedRx
All 50 states
SkinnyRx
48 states
Consultation Fee
ShedRx
Included
SkinnyRx
Included
Shipping
ShedRx
Free Shipping
SkinnyRx
Free Shipping
Cancel Anytime
ShedRx
Yes
SkinnyRx
Yes
Medical Support
ShedRx
Licensed doctors alongside health coaching and supplement advice
SkinnyRx
U.S.-licensed doctors who turn around prescription reviews in 24-48 hours

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

ShedRx: Detailed Look

ShedRx

Over 150K members and 5 ways to take it — shots, oral drops, lozenges, tablets, and pills

8.8/10
Very Good

Pros

  • More ways to take it than any rival: shots, oral drops, lozenges, tablets, and pills
  • Promise of 10% weight loss inside 9 months or your money back
  • Compounded formulas plus brand drugs like Wegovy and Zepbound
  • Membership tops 150,000, with coaching and supplements built in

Cons

  • Cost rises as your dose grows, reaching as much as $299/mo
  • Support feedback is uneven, and reply times can drag
Best For

People who want several ways to take their medication plus a money-back results promise

SkinnyRx: Detailed Look

SkinnyRx

A rapidly scaling GLP-1 service offering pills, sublinguals, and shots with Affirm financing

9.1/10
Excellent

Pros

  • Take it three ways — as a shot, under the tongue, or as a tablet
  • Overnight delivery is free and ships from FDA-regulated U.S. pharmacies
  • Billed month to month, so you're never locked into a contract
  • Thousands of verified Trustpilot reviews average a 4.8 out of 5

Cons

  • You'll pay cash — they don't run anything through insurance
  • Only compounded formulas here; brand-name versions aren't offered
Best For

People who want their GLP-1 in several formats — tablet, sublingual, or injection

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with ShedRx at $199/month. Semaglutide opens at $199/mo and climbs toward $299/mo on larger doses. Brand route runs $99/mo plus whatever the pharmacy charges..

You want the highest-rated program

SkinnyRx has the edge with a 9.1 rating.

You want affordable compounded options

SkinnyRx focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: ShedRx offers licensed doctors alongside health coaching and supplement advice, while SkinnyRx provides u.s.-licensed doctors who turn around prescription reviews in 24-48 hours.

ShedRx

Starting at $199/mo · Very Good

Visit ShedRx

SkinnyRx

Starting at $199/mo · Excellent

Visit SkinnyRx

Frequently Asked Questions

Is ShedRx better than SkinnyRx?

ShedRx has a 8.8 rating while SkinnyRx has a 9.1 rating. The better choice depends on your priorities — ShedRx is best for people who want several ways to take their medication plus a money-back results promise, while SkinnyRx is best for people who want their glp-1 in several formats — tablet, sublingual, or injection.

How much does ShedRx cost compared to SkinnyRx?

ShedRx starts at $199/month (semaglutide opens at $199/mo and climbs toward $299/mo on larger doses. brand route runs $99/mo plus whatever the pharmacy charges.), while SkinnyRx starts at $199/month (semaglutide runs $199/mo; tirzepatide climbs as high as $349/mo).

Do ShedRx and SkinnyRx accept insurance?

ShedRx does not accept insurance. SkinnyRx does not accept insurance.

Which GLP-1 medications does ShedRx offer vs SkinnyRx?

ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound. SkinnyRx offers Compounded Semaglutide (Injectable), Compounded Semaglutide (Sublingual), Compounded Tirzepatide (Injectable), Compounded Tirzepatide (Tablets).

Can I cancel ShedRx or SkinnyRx at any time?

ShedRx allows cancel anytime. SkinnyRx also allows cancel anytime.

Are ShedRx and SkinnyRx available in my state?

ShedRx is available in all 50 states. SkinnyRx is available in 48 states.

Not sure ShedRx or SkinnyRx is right for you?

Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.

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