ShedRx vs Sesame Care: Which GLP-1 Program Is Better? (2026)
We put ShedRx and Sesame Care head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend ShedRx
Between these two providers, ShedRx is our pick for most users. It offers a higher overall rating (8.8 vs 7.2), more affordable pricing. That said, Sesame Care may be the better fit if you are looking for insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately.
ShedRx scores 8.8/10 in our independent evaluation at $199/month, while Sesame Care scores 7.2/10 at $225/month. Both programs connect you with a licensed physician and deliver medication straight to your door. ShedRx also offers oral GLP-1 options for patients who prefer pills over injections. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | ShedRx | Sesame Care |
|---|---|---|
| Monthly Price | $199 | $225 |
| Rating | 8.8 / 10 | 7.2 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | Yes |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Included | $25-75 |
| Shipping | Free Shipping | Paid |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed doctors alongside health coaching and supplement advice | Licensed physicians booked one visit at a time |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
ShedRx: Detailed Look
ShedRx
Over 150K members and 5 ways to take it — shots, oral drops, lozenges, tablets, and pills
Pros
- More ways to take it than any rival: shots, oral drops, lozenges, tablets, and pills
- Promise of 10% weight loss inside 9 months or your money back
- Compounded formulas plus brand drugs like Wegovy and Zepbound
- Membership tops 150,000, with coaching and supplements built in
Cons
- Cost rises as your dose grows, reaching as much as $299/mo
- Support feedback is uneven, and reply times can drag
People who want several ways to take their medication plus a money-back results promise
Sesame Care: Detailed Look
Sesame Care
A low-cost telehealth marketplace that matches you with a doctor for as little as $25
Pros
- About the cheapest consult you'll find, with visits opening at $25
- Writes scripts for FDA-approved brand-name drugs
- Clear pay-per-visit pricing and nothing to subscribe to
- A broad bench of licensed physicians spanning all 50 states
Cons
- What the drug costs is billed on its own, apart from the visit fee
- No compounded route here — it's brand-name only, so the drug runs pricier
Insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with ShedRx at $199/month. Semaglutide opens at $199/mo and climbs toward $299/mo on larger doses. Brand route runs $99/mo plus whatever the pharmacy charges..
ShedRx has the edge with a 8.8 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
Compare their support: ShedRx offers licensed doctors alongside health coaching and supplement advice, while Sesame Care provides licensed physicians booked one visit at a time.
Sesame Care at $225/month may offer features that justify the premium.
Frequently Asked Questions
Is ShedRx better than Sesame Care?
ShedRx has a 8.8 rating while Sesame Care has a 7.2 rating. The better choice depends on your priorities — ShedRx is best for people who want several ways to take their medication plus a money-back results promise, while Sesame Care is best for insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately.
How much does ShedRx cost compared to Sesame Care?
ShedRx starts at $199/month (semaglutide opens at $199/mo and climbs toward $299/mo on larger doses. brand route runs $99/mo plus whatever the pharmacy charges.), while Sesame Care starts at $225/month (visits run $25-75, and the medication is billed separately at pharmacy rates ($200-1,400/mo). with insurance savings cards the total opens around $225/mo. the drug is not part of the visit fee.).
Do ShedRx and Sesame Care accept insurance?
ShedRx does not accept insurance. Sesame Care accepts insurance.
Which GLP-1 medications does ShedRx offer vs Sesame Care?
ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound. Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus.
Can I cancel ShedRx or Sesame Care at any time?
ShedRx allows cancel anytime. Sesame Care also allows cancel anytime.
Are ShedRx and Sesame Care available in my state?
ShedRx is available in all 50 states. Sesame Care is available in all 50 states.
Not sure ShedRx or Sesame Care is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.