ShedRx vs MyStart Health: Which GLP-1 Program Is Better? (2026)

We put ShedRx and MyStart Health head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend ShedRx

Between these two providers, ShedRx is our pick for most users. It offers a higher overall rating (8.8 vs 8.5), more affordable pricing. That said, MyStart Health may be the better fit if you are looking for people who value a money-back results pledge alongside a frozen price.

ShedRx scores 8.8/10 in our independent evaluation at $199/month, while MyStart Health scores 8.5/10 at $224/month. Both programs connect you with a licensed physician and deliver medication straight to your door. ShedRx also offers oral GLP-1 options for patients who prefer pills over injections. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
ShedRx
$199
MyStart Health
$224
Rating
ShedRx
8.8 / 10
MyStart Health
8.5 / 10
Medication Type
ShedRx
Brand & Compounded
MyStart Health
Brand & Compounded
Insurance Accepted
ShedRx
No
MyStart Health
No
States Available
ShedRx
All 50 states
MyStart Health
All 50 states
Consultation Fee
ShedRx
Included
MyStart Health
Free
Shipping
ShedRx
Free Shipping
MyStart Health
Free Shipping
Cancel Anytime
ShedRx
Yes
MyStart Health
Yes
Medical Support
ShedRx
Licensed doctors alongside health coaching and supplement advice
MyStart Health
U.S.-licensed doctors you can reach without any cap on clinician visits

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

ShedRx: Detailed Look

ShedRx

Over 150K members and 5 ways to take it — shots, oral drops, lozenges, tablets, and pills

8.8/10
Very Good

Pros

  • More ways to take it than any rival: shots, oral drops, lozenges, tablets, and pills
  • Promise of 10% weight loss inside 9 months or your money back
  • Compounded formulas plus brand drugs like Wegovy and Zepbound
  • Membership tops 150,000, with coaching and supplements built in

Cons

  • Cost rises as your dose grows, reaching as much as $299/mo
  • Support feedback is uneven, and reply times can drag
Best For

People who want several ways to take their medication plus a money-back results promise

MyStart Health: Detailed Look

MyStart Health

GLP-1 plans backed by a locked-in price and a results-or-refund pledge

8.5/10
Excellent

Pros

  • A locked rate means stepping up your dose never bumps the price
  • Drop 10% of your body weight inside four months or get your money back
  • One bundled price folds in free shipping and lab work
  • Reaches all 50 states and turns consultations around within a day

Cons

  • A handful of customers mention delays getting orders shipped out
  • Switching to tirzepatide costs a lot more at $429 a month
Best For

People who value a money-back results pledge alongside a frozen price

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with ShedRx at $199/month. Semaglutide opens at $199/mo and climbs toward $299/mo on larger doses. Brand route runs $99/mo plus whatever the pharmacy charges..

You want the highest-rated program

ShedRx has the edge with a 8.8 rating.

You want comprehensive medical support

Compare their support: ShedRx offers licensed doctors alongside health coaching and supplement advice, while MyStart Health provides u.s.-licensed doctors you can reach without any cap on clinician visits.

You are willing to invest more for premium care

MyStart Health at $224/month may offer features that justify the premium.

ShedRx

Starting at $199/mo · Very Good

Visit ShedRx

MyStart Health

Starting at $224/mo · Excellent

Visit MyStart Health

Frequently Asked Questions

Is ShedRx better than MyStart Health?

ShedRx has a 8.8 rating while MyStart Health has a 8.5 rating. The better choice depends on your priorities — ShedRx is best for people who want several ways to take their medication plus a money-back results promise, while MyStart Health is best for people who value a money-back results pledge alongside a frozen price.

How much does ShedRx cost compared to MyStart Health?

ShedRx starts at $199/month (semaglutide opens at $199/mo and climbs toward $299/mo on larger doses. brand route runs $99/mo plus whatever the pharmacy charges.), while MyStart Health starts at $224/month (normally $299/mo; code selflove25 trims 25% off to $224/mo. meds, labs, shipping, and unlimited clinician access all included).

Do ShedRx and MyStart Health accept insurance?

ShedRx does not accept insurance. MyStart Health does not accept insurance.

Which GLP-1 medications does ShedRx offer vs MyStart Health?

ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound. MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy.

Can I cancel ShedRx or MyStart Health at any time?

ShedRx allows cancel anytime. MyStart Health also allows cancel anytime.

Are ShedRx and MyStart Health available in my state?

ShedRx is available in all 50 states. MyStart Health is available in all 50 states.

Not sure ShedRx or MyStart Health is right for you?

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