ShedRx vs MangoRx: Which GLP-1 Program Is Better? (2026)

We put ShedRx and MangoRx head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend ShedRx

Between these two providers, ShedRx is our pick for most users. It offers a higher overall rating (8.8 vs 7.5), availability in all 50 states, both brand-name and compounded medication options. That said, MangoRx may be the better fit if you are looking for people who want one telehealth account that spans weight loss and men's health.

ShedRx scores 8.8/10 in our independent evaluation at $199/month, while MangoRx scores 7.5/10 at $195/month. Both programs connect you with a licensed physician and deliver medication straight to your door. ShedRx also offers oral GLP-1 options for patients who prefer pills over injections. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
ShedRx
$199
MangoRx
$195
Rating
ShedRx
8.8 / 10
MangoRx
7.5 / 10
Medication Type
ShedRx
Brand & Compounded
MangoRx
Compounded Only
Insurance Accepted
ShedRx
No
MangoRx
No
States Available
ShedRx
All 50 states
MangoRx
45 states
Consultation Fee
ShedRx
Included
MangoRx
Free
Shipping
ShedRx
Free Shipping
MangoRx
Free Shipping
Cancel Anytime
ShedRx
Yes
MangoRx
Yes
Medical Support
ShedRx
Licensed doctors alongside health coaching and supplement advice
MangoRx
Licensed U.S. physicians who stay available for continued support

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

ShedRx: Detailed Look

ShedRx

Over 150K members and 5 ways to take it — shots, oral drops, lozenges, tablets, and pills

8.8/10
Very Good

Pros

  • More ways to take it than any rival: shots, oral drops, lozenges, tablets, and pills
  • Promise of 10% weight loss inside 9 months or your money back
  • Compounded formulas plus brand drugs like Wegovy and Zepbound
  • Membership tops 150,000, with coaching and supplements built in

Cons

  • Cost rises as your dose grows, reaching as much as $299/mo
  • Support feedback is uneven, and reply times can drag
Best For

People who want several ways to take their medication plus a money-back results promise

MangoRx: Detailed Look

MangoRx

A single telehealth service spanning weight loss, men's health, and broader wellness needs

7.5/10
Good

Pros

  • Handles more than weight loss — ED, hair loss, and skincare too
  • Every prescription is written by a licensed U.S. physician
  • Shipping is free on whatever you order
  • An easy online intake that skips the need for an appointment

Cons

  • You won't see the full pricing until you finish the intake form
  • Stocks compounded formulas only, with no brand-name versions
Best For

People who want one telehealth account that spans weight loss and men's health

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with MangoRx at $195/month. A ballpark opening figure for the GLP-1 program.

You want the highest-rated program

ShedRx has the edge with a 8.8 rating.

You want affordable compounded options

MangoRx focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: ShedRx offers licensed doctors alongside health coaching and supplement advice, while MangoRx provides licensed u.s. physicians who stay available for continued support.

You are willing to invest more for premium care

ShedRx at $199/month may offer features that justify the premium.

ShedRx

Starting at $199/mo · Very Good

Visit ShedRx

MangoRx

Starting at $195/mo · Good

Visit MangoRx

Frequently Asked Questions

Is ShedRx better than MangoRx?

ShedRx has a 8.8 rating while MangoRx has a 7.5 rating. The better choice depends on your priorities — ShedRx is best for people who want several ways to take their medication plus a money-back results promise, while MangoRx is best for people who want one telehealth account that spans weight loss and men's health.

How much does ShedRx cost compared to MangoRx?

ShedRx starts at $199/month (semaglutide opens at $199/mo and climbs toward $299/mo on larger doses. brand route runs $99/mo plus whatever the pharmacy charges.), while MangoRx starts at $195/month (a ballpark opening figure for the glp-1 program).

Do ShedRx and MangoRx accept insurance?

ShedRx does not accept insurance. MangoRx does not accept insurance.

Which GLP-1 medications does ShedRx offer vs MangoRx?

ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound. MangoRx offers Compounded Semaglutide, Compounded Tirzepatide.

Can I cancel ShedRx or MangoRx at any time?

ShedRx allows cancel anytime. MangoRx also allows cancel anytime.

Are ShedRx and MangoRx available in my state?

ShedRx is available in all 50 states. MangoRx is available in 45 states.

Not sure ShedRx or MangoRx is right for you?

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