ShedRx vs Enhance MD: Which GLP-1 Program Is Better? (2026)
We put ShedRx and Enhance MD head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend ShedRx
Between these two providers, ShedRx is our pick for most users. It offers a higher overall rating (8.8 vs 8.3), more affordable pricing. That said, Enhance MD may be the better fit if you are looking for cost-minded patients curious about stacking combination therapies.
ShedRx scores 8.8/10 in our independent evaluation at $199/month, while Enhance MD scores 8.3/10 at $249/month. Both programs connect you with a licensed physician and deliver medication straight to your door. ShedRx also offers oral GLP-1 options for patients who prefer pills over injections. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | ShedRx | Enhance MD |
|---|---|---|
| Monthly Price | $199 | $249 |
| Rating | 8.8 / 10 | 8.3 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed doctors alongside health coaching and supplement advice | Board-certified doctors |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
ShedRx: Detailed Look
ShedRx
Over 150K members and 5 ways to take it — shots, oral drops, lozenges, tablets, and pills
Pros
- More ways to take it than any rival: shots, oral drops, lozenges, tablets, and pills
- Promise of 10% weight loss inside 9 months or your money back
- Compounded formulas plus brand drugs like Wegovy and Zepbound
- Membership tops 150,000, with coaching and supplements built in
Cons
- Cost rises as your dose grows, reaching as much as $299/mo
- Support feedback is uneven, and reply times can drag
People who want several ways to take their medication plus a money-back results promise
Enhance MD: Detailed Look
Enhance MD
Doctor-directed weight management that also offers NAD+ add-ons
Pros
- Wallet-friendly way in, with pricing that begins at $115/month
- An uncommon NAD+ therapy choice to pair with your GLP-1
- Every protocol is overseen by board-certified doctors
Cons
- Claims that NAD+ aids weight loss aren't well supported by trials
- It's hazy about which drugs are compounded versus brand-name
Cost-minded patients curious about stacking combination therapies
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with ShedRx at $199/month. Semaglutide opens at $199/mo and climbs toward $299/mo on larger doses. Brand route runs $99/mo plus whatever the pharmacy charges..
ShedRx has the edge with a 8.8 rating.
Compare their support: ShedRx offers licensed doctors alongside health coaching and supplement advice, while Enhance MD provides board-certified doctors.
Enhance MD at $249/month may offer features that justify the premium.
Frequently Asked Questions
Is ShedRx better than Enhance MD?
ShedRx has a 8.8 rating while Enhance MD has a 8.3 rating. The better choice depends on your priorities — ShedRx is best for people who want several ways to take their medication plus a money-back results promise, while Enhance MD is best for cost-minded patients curious about stacking combination therapies.
How much does ShedRx cost compared to Enhance MD?
ShedRx starts at $199/month (semaglutide opens at $199/mo and climbs toward $299/mo on larger doses. brand route runs $99/mo plus whatever the pharmacy charges.), while Enhance MD starts at $249/month (semaglutide runs $249/mo and tirzepatide $379/mo, with yearly plans trimming roughly 15%).
Do ShedRx and Enhance MD accept insurance?
ShedRx does not accept insurance. Enhance MD does not accept insurance.
Which GLP-1 medications does ShedRx offer vs Enhance MD?
ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound. Enhance MD offers Semaglutide, Tirzepatide, NAD+.
Can I cancel ShedRx or Enhance MD at any time?
ShedRx allows cancel anytime. Enhance MD also allows cancel anytime.
Are ShedRx and Enhance MD available in my state?
ShedRx is available in all 50 states. Enhance MD is available in all 50 states.
Not sure ShedRx or Enhance MD is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.