ShedRx vs DudeMeds: Which GLP-1 Program Is Better? (2026)

We put ShedRx and DudeMeds head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend ShedRx

Between these two providers, ShedRx is our pick for most users. It offers a higher overall rating (8.8 vs 5.7), availability in all 50 states, both brand-name and compounded medication options. That said, DudeMeds may be the better fit if you are looking for men who'd rather get their glp-1 weight loss from a male-focused platform.

ShedRx scores 8.8/10 in our independent evaluation at $199/month, while DudeMeds scores 5.7/10 at $199/month. Both programs connect you with a licensed physician and deliver medication straight to your door. ShedRx also offers oral GLP-1 options for patients who prefer pills over injections. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
ShedRx
$199
DudeMeds
$199
Rating
ShedRx
8.8 / 10
DudeMeds
5.7 / 10
Medication Type
ShedRx
Brand & Compounded
DudeMeds
Compounded Only
Insurance Accepted
ShedRx
No
DudeMeds
No
States Available
ShedRx
All 50 states
DudeMeds
46 states
Consultation Fee
ShedRx
Included
DudeMeds
Free
Shipping
ShedRx
Free Shipping
DudeMeds
Free Shipping
Cancel Anytime
ShedRx
Yes
DudeMeds
Yes
Medical Support
ShedRx
Licensed doctors alongside health coaching and supplement advice
DudeMeds
Licensed clinicians accessible through an always-on patient portal

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

ShedRx: Detailed Look

ShedRx

Over 150K members and 5 ways to take it — shots, oral drops, lozenges, tablets, and pills

8.8/10
Very Good

Pros

  • More ways to take it than any rival: shots, oral drops, lozenges, tablets, and pills
  • Promise of 10% weight loss inside 9 months or your money back
  • Compounded formulas plus brand drugs like Wegovy and Zepbound
  • Membership tops 150,000, with coaching and supplements built in

Cons

  • Cost rises as your dose grows, reaching as much as $299/mo
  • Support feedback is uneven, and reply times can drag
Best For

People who want several ways to take their medication plus a money-back results promise

DudeMeds: Detailed Look

DudeMeds

Men's health service delivering GLP-1 weight loss as pills or injections

5.7/10
Below Average

Pros

  • No membership charge, no doctor charge, and nothing buried in the fine print
  • Shipping costs nothing and goes out within 48 hours of approval
  • An always-open patient portal puts clinicians within reach
  • Pick your GLP-1 as either an oral dose or an injection

Cons

  • You won't see the price until you've worked through the intake
  • It started life as a men's TRT clinic, so weight loss is a newer add-on
Best For

Men who'd rather get their GLP-1 weight loss from a male-focused platform

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with ShedRx at $199/month. Semaglutide opens at $199/mo and climbs toward $299/mo on larger doses. Brand route runs $99/mo plus whatever the pharmacy charges..

You want the highest-rated program

ShedRx has the edge with a 8.8 rating.

You want affordable compounded options

DudeMeds focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: ShedRx offers licensed doctors alongside health coaching and supplement advice, while DudeMeds provides licensed clinicians accessible through an always-on patient portal.

ShedRx

Starting at $199/mo · Very Good

Visit ShedRx

DudeMeds

Starting at $199/mo · Below Average

Visit DudeMeds

Frequently Asked Questions

Is ShedRx better than DudeMeds?

ShedRx has a 8.8 rating while DudeMeds has a 5.7 rating. The better choice depends on your priorities — ShedRx is best for people who want several ways to take their medication plus a money-back results promise, while DudeMeds is best for men who'd rather get their glp-1 weight loss from a male-focused platform.

How much does ShedRx cost compared to DudeMeds?

ShedRx starts at $199/month (semaglutide opens at $199/mo and climbs toward $299/mo on larger doses. brand route runs $99/mo plus whatever the pharmacy charges.), while DudeMeds starts at $199/month (a ballpark figure — the real number shows up once you finish the intake quiz).

Do ShedRx and DudeMeds accept insurance?

ShedRx does not accept insurance. DudeMeds does not accept insurance.

Which GLP-1 medications does ShedRx offer vs DudeMeds?

ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound. DudeMeds offers Compounded Semaglutide (Oral), Compounded Semaglutide (Injectable), Compounded Tirzepatide.

Can I cancel ShedRx or DudeMeds at any time?

ShedRx allows cancel anytime. DudeMeds also allows cancel anytime.

Are ShedRx and DudeMeds available in my state?

ShedRx is available in all 50 states. DudeMeds is available in 46 states.

Not sure ShedRx or DudeMeds is right for you?

Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.

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