Sesame Care vs Trimi: Which GLP-1 Program Is Better? (2026)
We put Sesame Care and Trimi head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend Trimi
Between these two providers, Trimi is our pick for most users. It offers a higher overall rating (8.1 vs 7.2), more affordable pricing. That said, Sesame Care may be the better fit if you are looking for insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately.
Trimi scores 8.1/10 in our independent evaluation at $99/month, while Sesame Care scores 7.2/10 at $225/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | Sesame Care | Trimi |
|---|---|---|
| Monthly Price | $225 | $99 |
| Rating | 7.2 / 10 | 8.1 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | Yes | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | $25-75 | Free |
| Shipping | Paid | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed physicians booked one visit at a time | US-licensed clinicians via Arora Health |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
Sesame Care: Detailed Look
Sesame Care
A low-cost telehealth marketplace that matches you with a doctor for as little as $25
Pros
- About the cheapest consult you'll find, with visits opening at $25
- Writes scripts for FDA-approved brand-name drugs
- Clear pay-per-visit pricing and nothing to subscribe to
- A broad bench of licensed physicians spanning all 50 states
Cons
- What the drug costs is billed on its own, apart from the visit fee
- No compounded route here — it's brand-name only, so the drug runs pricier
Insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately
Trimi: Detailed Look
Trimi
Flat-price compounded GLP-1 — your cost stays the same as your dose climbs
Pros
- Flat monthly price that doesn't change as your dose is adjusted
- Compounded semaglutide from $99/mo, tirzepatide from $125/mo
- US-licensed clinicians (via Arora Health) prescribing in all 50 states
- 100% online with medication shipped to your door
Cons
- The lowest $99/$125 pricing requires an annual plan
- Compounded medications are not FDA-approved
Self-pay patients who want a flat, predictable price as their dose increases
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with Trimi at $99/month. Compounded semaglutide $99/mo and tirzepatide $125/mo on annual plans — and the price doesn't rise as your dose increases..
Trimi has the edge with a 8.1 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
Trimi focuses on compounded medications at a lower price point.
Compare their support: Sesame Care offers licensed physicians booked one visit at a time, while Trimi provides us-licensed clinicians via arora health.
Sesame Care at $225/month may offer features that justify the premium.
Frequently Asked Questions
Is Sesame Care better than Trimi?
Sesame Care has a 7.2 rating while Trimi has a 8.1 rating. The better choice depends on your priorities — Sesame Care is best for insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately, while Trimi is best for self-pay patients who want a flat, predictable price as their dose increases.
How much does Sesame Care cost compared to Trimi?
Sesame Care starts at $225/month (visits run $25-75, and the medication is billed separately at pharmacy rates ($200-1,400/mo). with insurance savings cards the total opens around $225/mo. the drug is not part of the visit fee.), while Trimi starts at $99/month (compounded semaglutide $99/mo and tirzepatide $125/mo on annual plans — and the price doesn't rise as your dose increases.).
Do Sesame Care and Trimi accept insurance?
Sesame Care accepts insurance. Trimi does not accept insurance.
Which GLP-1 medications does Sesame Care offer vs Trimi?
Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus. Trimi offers Compounded Semaglutide, Compounded Tirzepatide.
Can I cancel Sesame Care or Trimi at any time?
Sesame Care allows cancel anytime. Trimi also allows cancel anytime.
Are Sesame Care and Trimi available in my state?
Sesame Care is available in all 50 states. Trimi is available in all 50 states.
Not sure Sesame Care or Trimi is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.